Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6297807 | 0.98 | NPC1 (0.70) | NPC1TAAR1PNPMAOAMAOB | |
| SCHEMBL16591628 | 0.81 | NPC1 (0.67) | NPC1RAB9AHTT | |
| SCHEMBL16586060 | 0.81 | NPC1 (0.67) | NPC1TAAR1PNPMRGPRX1KDM4C | |
| SCHEMBL5692951 | 0.80 | NPC1 (0.51) | NPC1TAAR1PNPKDM4CADORA3 | |
| SCHEMBL24496667 | 0.79 | NPC1 (0.63) | NPC1KDM4CHTT | |
| Hydrochloric Acid SCHEMBL5850789 | 0.78 | NPC1 (0.54) | NPC1TAAR1PNPKDM4CADORA3 | |
| SCHEMBL455536 | 0.78 | MEN1 (0.50) | NPC1MAOAMAOBRAB9ATDP1 | |
| SCHEMBL3422016 | 0.78 | MEN1 (0.50) | NPC1MAOAMAOBRAB9ATDP1 | |
| SCHEMBL5154356 | 0.78 | MEN1 (0.50) | NPC1MAOAMAOBRAB9ATDP1 | |
| SCHEMBL6797939 | 0.77 | NPC1 (0.61) | NPC1KDM4CHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1752192-B1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | PROCTER & GAMBLE (US) | 2010-02-03 | — | — | EP | claimed |
| US-7491244-B2 | Oxidizing hair coloring agents containing m-aminophenol derivatives | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | claimed |
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | claimed |
| EP-1760072-A1 | 1,3-diaminobenzene derivatives and colorants comprising these compounds | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | claimed |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | claimed |
| EP-1752192-A1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | Wella Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | claimed |
| US-20070022546-A1 | 3-Amino-2-aminomethylphenol derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-02-01 | — | — | US | claimed |
| US-6887281-B2 | N-heteroarylmethyl-p-phenylenediamine derivatives as well as oxidation dyeing agents containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-05-03 | — | — | US | claimed |
| US-6849097-B2 | N-heteroarylmethyl-p-phnylendiamine derivatives and compounds containing oxidationcoloring agents | WELLA AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | claimed |
| US-20050015898-A1 | N-heteroarylmethyl-p-phenylenediamine derivatives as well as oxidation dyeing agents containing these compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2005-01-27 | — | — | US | claimed |
| EP-1313724-B1 | N-HETEROARYLMETHYL-P-PHENYLENDIAMINE DERIVATIVES AND COMPOUNDS CONTAINING OXIDATION COLOURING AGENTS | WELLA AG (DE) | 2004-04-28 | — | — | EP | claimed |
| EP-1313724-A1 | N-HETEROARYLMETHYL-P-PHENYLENDIAMINE DERIVATIVES AND COMPOUNDS CONTAINING OXIDATION COLOURING AGENTS | Wella Aktiengesellschaft (DE) | 2003-05-28 | — | — | EP | claimed |
| US-20030070240-A1 | N-heteroarylmethyl-p-phnylendiamine derivatives and compounds containing oxidationcoloring agents | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-04-17 | — | — | US | claimed |
| WO-2002018365-A1 | N-HETEROARYLMETHYL-P-PHENYLENDIAMINE DERIVATIVES AND COMPOUNDS CONTAINING OXIDATION COLOURING AGENTS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-07 | — | — | WO | claimed |
| US-12133906-B2 | Delivery particle | THE PROCTER & GAMBLE COMPANY (US) | 2024-11-05 | — | — | US | disclosed |
| US-20220409497-A1 | DELIVERY PARTICLE | PROCTER & GAMBLE (US) | 2022-12-29 | — | — | US | disclosed |
| EP-3733827-A1 | DELIVERY PARTICLES | The Procter & Gamble Company (US) | 2020-11-04 | — | — | EP | disclosed |
| EP-1313724-A1 | N-HETEROARYLMETHYL-P-PHENYLENDIAMINE DERIVATIVES AND COMPOUNDS CONTAINING OXIDATION COLOURING AGENTS | Wella Aktiengesellschaft (DE) | 2003-05-28 | — | — | EP | disclosed |
| US-20030070240-A1 | N-heteroarylmethyl-p-phnylendiamine derivatives and compounds containing oxidationcoloring agents | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-04-17 | — | — | US | disclosed |
| WO-2002018365-A1 | N-HETEROARYLMETHYL-P-PHENYLENDIAMINE DERIVATIVES AND COMPOUNDS CONTAINING OXIDATION COLOURING AGENTS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220409497-A1 | DELIVERY PARTICLE | LIPA, CHMP4B, SLC46A1 | NPC1 100/4885TAAR1 3178/4885PNP 1371/4885 |
| US-20070022546-A1 | 3-Amino-2-aminomethylphenol derivatives and colorants comprising these compounds | KRT18, COL2A1, COL1A1 | NPC1 4873/4885TAAR1 3508/4885PNP 3182/4885 |
| US-20030070240-A1 | N-heteroarylmethyl-p-phnylendiamine derivatives and compounds containing oxidationcoloring agents | PNMT, PAH, CYP2E1 | NPC1 1682/4885TAAR1 412/4885PNP 1419/4885 |
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | KRT18, DSP, DSG1 | NPC1 4839/4885TAAR1 3094/4885PNP 2035/4885 |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | TACR1, KRT18, AKR1C4 | NPC1 4801/4885TAAR1 50/4885PNP 4713/4885 |
| US-12133906-B2 | Delivery particle | LIPA, CHMP4B, SLC46A1 | NPC1 100/4885TAAR1 3178/4885PNP 1371/4885 |
| US-20050015898-A1 | N-heteroarylmethyl-p-phenylenediamine derivatives as well as oxidation dyeing agents containing these compounds | TYR, PNMT, DDT | NPC1 2653/4885TAAR1 460/4885PNP 2076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.