Tert-Butylbenzene

Tert-Butylbenzene

SCHEMBL454718

CC(C)(C)c1ccccc1.CC=O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.44
▸ MAPT P10636 2/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ TSHR P16473 2/20 0.42
▸ CYP2C19 P33261 1/20 0.41
▸ HIF1A Q16665 1/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ TAAR1 Q96RJ0 1/20 0.41
▸ ALOX15 P16050 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ TRPV1 Q8NER1 1/20 0.41
▸ ESRRG P62508 1/20 0.41
▸ LMNA P02545 2/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ SRD5A2 P31213 1/20 0.40
▸ TYR P14679 1/20 0.40
▸ HDAC3 O15379 1/20 0.40
▸ HDAC4 P56524 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butylbenzene SCHEMBL27332948 0.87 MAPK1 (0.42) MAPK1MAPTKMT2ATDP1L3MBTL1
Tert-Butylbenzene SCHEMBL5965959 0.87 MAPT (0.46) MAPK1MAPTKMT2ATDP1L3MBTL1
Tert-Butylbenzene SCHEMBL27294369 0.87 MAPT (0.46) MAPK1MAPTKMT2ATDP1L3MBTL1
Acetaldehyde SCHEMBL27849991 0.86 KIF11 (0.50) MAPTKMT2ATDP1L3MBTL1TSHR
Tert-Butylbenzene SCHEMBL337648 0.86 MAPK1 (0.55) MAPK1MAPTKMT2ATDP1L3MBTL1
Tert-Butylbenzene SCHEMBL2568053 0.86 MAPK1 (0.55) MAPK1MAPTKMT2ATDP1L3MBTL1
Tert-Butylbenzene SCHEMBL22264599 0.86 MAPK1 (0.55) MAPK1MAPTKMT2ATDP1L3MBTL1
Tert-Butylbenzene SCHEMBL22264597 0.86 MAPK1 (0.55) MAPK1MAPTKMT2ATDP1L3MBTL1
Tert-Butylbenzene SCHEMBL18889 0.86 MAPK1 (0.55) MAPK1MAPTKMT2ATDP1L3MBTL1
Tert-Butylbenzene SCHEMBL28671109 0.85 KIF11 (0.41) MAPK1MAPTKMT2ATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4106822-A1 BAD-ODOR CONTROL USING ENCAPSULATION TECHNOLOGIES CONTAINING NEUTRALIZING AGENT Henkel AG & Co. KGaA (DE) 2022-12-28 — — EP claimed
EP-3713921-A1 HYDROLYTICALLY LABILE HETEROCYCLES OF ODORIFEROUS KETONES OR ODORIFEROUS ALDEHYDES Henkel AG & Co. KGaA (DE) 2020-09-30 — — EP claimed
EP-1976855-B1 1-AZA-3,7-DIOXABICYCLO[3.3.0]OCTANE COMPOUNDS AND THEIR USE AS PRO-FRAGRANCES HENKEL AG & CO KGAA (DE) 2012-08-15 — — EP claimed
WO-2009156278-A1 POLYMERIC PRO-FRAGRANCE HENKEL AG & CO. KGAA (DE) 2009-12-30 — — WO claimed
WO-2009153209-A1 MODIFIED POLYMERIC PRO-FRAGRANCE HENKEL AG & CO. KGAA (DE) 2009-12-23 — — WO claimed
US-20060205632-A1 Pro-fragrance and pro-flavorant compositions FLEXITRAL, INC. 2006-09-14 — — US claimed
US-12616644-B2 Polyurethane gels GRANT INDUSTRIES, INC. (US) 2026-05-05 — — US disclosed
US-12583876-B2 Branched organosilicon compound, method of preparing same, and related compositions DOW SILICONES CORPORATION (US) 2026-03-24 — — US disclosed
US-12583972-B2 Non-isocyanate polyurethane elastomers and compositions comprising such elastomers GRANT INDUSTRIES, INC. (US) 2026-03-24 — — US disclosed
US-12577511-B2 Agent containing emulsifier and microcapsules HENKEL AG & CO. KGAA (DE) 2026-03-17 — — US disclosed
US-20260042887-A1 NON-ISOCYANATE POLYURETHANE ELASTOMERS AND COMPOSITIONS COMPRISING SUCH ELASTOMERS GRANT INDUSTRIES, INC. (US) 2026-02-12 — — US disclosed
US-12521324-B2 Polyurethane gels GRANT INDUSTRIES, INC. (US) 2026-01-13 — — US disclosed
US-12398270-B2 Acrylate-functional branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-08-26 — — US disclosed
WO-2000002991-A1 AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT THE PROCTER & GAMBLE COMPANY (US) 2000-01-20 — — WO disclosed
WO-2000002982-A2 LAUNDRY AND CLEANING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-01-20 — — WO disclosed
EP-0971027-A1 Amine reaction compounds comprising one or more active ingredient THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 — — EP disclosed
EP-0971026-A1 Laundry and cleaning compositions THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 — — EP disclosed
EP-0971021-A1 Process for producing particles of amine reaction product THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 — — EP disclosed
EP-0971024-A1 Laundry and cleaning compositions THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 — — EP disclosed
EP-0971025-A1 Amine reaction compounds comprising one or more active ingredient THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577511-B2 Agent containing emulsifier and microcapsules LIPA, CUTA, MGLL MAPK1 3823/4885MAPT 483/4885KMT2A 1750/4885
US-12583972-B2 Non-isocyanate polyurethane elastomers and compositions comprising such elastomers NAF1, PUF60, NONO MAPK1 3466/4885MAPT 2305/4885KMT2A 3349/4885
US-12616644-B2 Polyurethane gels DAGLB, DEGS1, CUTA MAPK1 4440/4885MAPT 2788/4885KMT2A 4437/4885
US-12583876-B2 Branched organosilicon compound, method of preparing same, and related compositions OXSR1, BRS3, NPSR1 MAPK1 3505/4885MAPT 4513/4885KMT2A 2510/4885
US-20260042887-A1 NON-ISOCYANATE POLYURETHANE ELASTOMERS AND COMPOSITIONS COMPRISING SUCH ELASTOMERS PCTP, NONO, PUF60 MAPK1 4046/4885MAPT 1593/4885KMT2A 3751/4885
US-20060205632-A1 Pro-fragrance and pro-flavorant compositions TAS2R10, TAS2R9, OR10J3 MAPK1 2995/4885MAPT 3009/4885KMT2A 3814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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