Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.54 |
| ▸ | CA2 | P00918 | 10/20 | 0.54 |
| ▸ | CA9 | Q16790 | 10/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LPL | P06858 | 3/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20843039 | 0.85 | CA1 (0.43) | CA1CA2CA9CA12CA3 | |
| SCHEMBL1255934 | 0.85 | AAK1 (0.54) | CA1CA2CA9CA12CA3 | |
| SCHEMBL28602436 | 0.85 | CA1 (0.50) | CA1CA2CA9CA12CA3 | |
| SCHEMBL1332747 | 0.84 | CA1 (0.52) | CA1CA2CA9CA12CA3 | |
| SCHEMBL706622 | 0.83 | CA1 (0.57) | CA1CA2CA9CA12CA3 | |
| SCHEMBL1284377 | 0.83 | CA1 (0.57) | CA1CA2CA9CA12CA3 | |
| SCHEMBL27374855 | 0.83 | CA1 (0.54) | CA1CA2CA9CA12CA3 | |
| SCHEMBL488835 | 0.83 | ALDH1A1 (0.58) | CA1CA2CA9SMN1; SMN2HPGD | |
| SCHEMBL17394174 | 0.83 | SMN1; SMN2 (0.55) | CA1CA2CA9CA12CA3 | |
| SCHEMBL22071360 | 0.82 | CA1 (0.54) | CA1CA2CA9CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695251-A1 | IMIDAZO[1,2-A]PYRAZINE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2026-02-18 | — | — | EP | disclosed |
| EP-4694686-A1 | FUNGICIDAL COMPOSITIONS | Syngenta Crop Protection AG (CH) | 2026-02-18 | — | — | EP | disclosed |
| EP-4695246-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2026-02-18 | — | — | EP | disclosed |
| EP-4695252-A1 | IMIDAZO[1,2-A]PYRAZINE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2026-02-18 | — | — | EP | disclosed |
| US-20240425500-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-12-26 | — | — | US | disclosed |
| WO-2024213720-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2024-10-17 | — | — | WO | disclosed |
| WO-2024213659-A1 | IMIDAZO[1,2-A]PYRAZINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-10-17 | — | — | WO | disclosed |
| WO-2024213656-A1 | IMIDAZO[1,2-A]PYRAZINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-10-17 | — | — | WO | disclosed |
| WO-2024213653-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-10-17 | — | — | WO | disclosed |
| US-20240287022-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-08-29 | — | — | US | disclosed |
| US-20120108574-A1 | Substituted Benzo-Imidazo-Pyrido-Diazepine Compounds | ARQULE, INC. (US) | 2012-05-03 | — | — | US | disclosed |
| US-20120108574-A1 | Substituted Benzo-Imidazo-Pyrido-Diazepine Compounds | ARQULE, INC. (US) | 2012-05-03 | — | — | US | disclosed |
| US-20110281857-A1 | PI3K/MTOR KINASE INHIBITORS | XCOVERY HOLDING COMPANY, LLC (US) | 2011-11-17 | — | — | US | disclosed |
| WO-2010056320-A2 | PI3K/MTOR KINASE INHIBITORS | TYROGENEX, INC. (US) | 2010-05-20 | — | — | WO | disclosed |
| US-20060287356-A1 | dietetics or antidiabetic agents such as 4-hydroxy-3-(4'-hydroxy-1,1'-biphenyl-4-yl)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile, used for prophylaxis of metabolic disorders | IYENGAR RAJESH R | 2006-12-21 | — | — | US | disclosed |
| US-7119205-B2 | Thienopyridones as AMPK activators for the treatment of diabetes and obesity | ABBOTT LABORATORIES (US) | 2006-10-10 | — | — | US | disclosed |
| US-7074785-B2 | Δ1-pyrrolines used as pesticides | BAYER CROPSCIENCE AG (DE) | 2006-07-11 | — | — | US | disclosed |
| US-20060142369-A1 | Delta 1-pyrrolines used as pesticides | SEITZ THOMAS | 2006-06-29 | — | — | US | disclosed |
| US-20050038068-A1 | Thienopyridones as AMPK activators for the treatment of diabetes and obesity | ABBVIE INC. | 2005-02-17 | — | — | US | disclosed |
| US-20050014650-A1 | Delta 1-pyrrolines used as pesticides | BAYER CROPSCIENCE AG (DE) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142369-A1 | Delta 1-pyrrolines used as pesticides | DDT, CHRM1, OPRD1 | CA1 1357/4885CA2 1858/4885CA9 3745/4885 |
| US-20060287356-A1 | dietetics or antidiabetic agents such as 4-hydroxy-3-(4'-hydroxy-1,1'-biphenyl-4-yl)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile, used for prophylaxis of metabolic disorders | GPR119, FABP4, ADIPOR1 | CA1 4443/4885CA2 2549/4885CA9 3765/4885 |
| US-20120108574-A1 | Substituted Benzo-Imidazo-Pyrido-Diazepine Compounds | BRD4, BRPF3, BRD3 | CA1 3854/4885CA2 3143/4885CA9 3760/4885 |
| US-20050038068-A1 | Thienopyridones as AMPK activators for the treatment of diabetes and obesity | PRKAG1, PRKAG3, PRKAG2 | CA1 4878/4885CA2 4106/4885CA9 4721/4885 |
| US-20240425500-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES | IDO1, CYP1A1, CYP4Z1 | CA1 2212/4885CA2 2461/4885CA9 3720/4885 |
| US-20110281857-A1 | PI3K/MTOR KINASE INHIBITORS | MTOR, PIK3CA, PI4KA | CA1 4870/4885CA2 4605/4885CA9 4227/4885 |
| US-20050014650-A1 | Delta 1-pyrrolines used as pesticides | CHRM1, DDT, CHRND | CA1 1278/4885CA2 1735/4885CA9 3880/4885 |
| US-20240287022-A1 | IL4I1 INHIBITORS AND METHODS OF USE | IL4I1, IL4, IL1RN | CA1 3686/4885CA2 2081/4885CA9 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.