Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 known ✓ | P09917 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721515 | 0.86 | ALDH1A1 (0.53) | ALDH1A1HTTTSHRKMT2AAPEX1 | |
| SCHEMBL309080 | 0.86 | ALDH1A1 (0.53) | ALDH1A1HTTTSHRKMT2AAPEX1 | |
| SCHEMBL19077949 | 0.83 | MAPK1 (0.63) | ALDH1A1HTTTSHRKMT2AAPEX1 | |
| SCHEMBL14088971 | 0.83 | MAPK1 (0.63) | ALDH1A1HTTTSHRKMT2AAPEX1 | |
| SCHEMBL9134694 | 0.83 | MAPK1 (0.63) | ALDH1A1HTTTSHRKMT2AAPEX1 | |
| SCHEMBL8655629 | 0.80 | HTT (0.53) | HTTTSHRKMT2AAPEX1LMNA | |
| SCHEMBL27891076 | 0.80 | HTT (0.56) | HTTTSHRKMT2AAPEX1LMNA | |
| SCHEMBL29696485 | 0.78 | HTT (0.57) | ALDH1A1HTTTSHRKMT2AAPEX1 | |
| SCHEMBL28809399 | 0.78 | HTT (0.57) | ALDH1A1HTTTSHRKMT2AAPEX1 | |
| SCHEMBL23610316 | 0.77 | HTT (0.75) | ALDH1A1HTTTSHRLMNANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138222-B2 | Whitening agents for cellulosic substrates | MILLIKEN & COMPANY (US) | 2012-03-20 | — | — | US | disclosed |
| WO-2011146602-A2 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & COMPANY (US) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011146604-A2 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & COMPANY (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20110283466-A1 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & COMPANY | 2011-11-24 | — | — | US | disclosed |
| US-20110287999-A1 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & COMPANY | 2011-11-24 | — | — | US | disclosed |
| US-8022100-B2 | Whitening agents for cellulosic substrates | MILLIKEN & CO. (US) | 2011-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110283466-A1 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | DBN1, DKC1, DDB1 | ALOX5 3721/4885ALDH1A1 514/4885HTT 393/4885 |
| US-20110287999-A1 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | DBN1, AOC1, RARB | ALOX5 2501/4885ALDH1A1 546/4885HTT 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.