Dimethylamine

Dimethylamine

SCHEMBL4559644

C=CCOC(=O)CN.CNC

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
TDP1 Q9NUW8 1/20 0.43
MAPT P10636 1/20 0.43
CACNA1B Q00975 1/20 0.43
APBA1 Q02410 1/20 0.43
ALDH1A1 P00352 6/20 0.37
GAA P10253 1/20 0.37
CYP3A4 P08684 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HSD17B10 Q99714 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
PKM P14618 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 2/20 0.33
EPHX2 P34913 1/20 0.33
KDM4E B2RXH2 3/20 0.33
HPGD P15428 2/20 0.33
TP53 P04637 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL214047 0.91
SCHEMBL19032768 0.89
Hydrochloric Acid SCHEMBL638709 0.89
Methylene Chloride SCHEMBL11133207 0.85 TSHR (0.44) TSHRTDP1MAPTCACNA1BAPBA1
SCHEMBL10458336 0.82 TSHR (0.42) TSHRTDP1MAPTCACNA1BAPBA1
Butyl Alcohol SCHEMBL21381547 0.80 TSHR (0.57) TSHRTDP1MAPTCACNA1BAPBA1
SCHEMBL11651722 0.79 TSHR (0.41) TSHRTDP1MAPTCACNA1BAPBA1
Trifluoroacetic Acid SCHEMBL27751013 0.79 TSHR (0.40) TSHRTDP1MAPTCACNA1BAPBA1
SCHEMBL9513 0.78 TSHR (0.50) TSHRTDP1MAPTCACNA1BAPBA1
Glycinebetaine SCHEMBL16020999 0.77 TSHR (0.39) TSHRTDP1MAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240000746-A1 New Cooling Agents and Preparations Containing Them SYMRISE AG (DE) 2024-01-04 US disclosed
EP-3432858-B1 NON-THERAPEUTIC USE OF CARNOSINES SYMRISE AG (DE) 2023-12-27 EP disclosed
EP-4288156-A1 AGENT FOR DYEING KERATINOUS MATERIAL, CONTAINING AT LEAST TWO ORGANOSILICON COMPOUNDS THAT ARE DIFFERENT FROM EACH OTHER, AT LEAST ONE PIGMENT AND AT LEAST ONE LIQUID FATTY COMPONENT AND/OR A SOLVENT Henkel AG & Co. KGaA (DE) 2023-12-13 EP disclosed
EP-4284329-A1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A DYEING COMPOUND, A SEALING REAGENT AND A POST-TREATMENT AGENT Henkel AG & Co. KGaA (DE) 2023-12-06 EP disclosed
EP-4225449-A1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A DYEING COMPOUND, A SEALING REAGENT AND A PRE-TREATMENT AGENT Henkel AG & Co. KGaA (DE) 2023-08-16 EP disclosed
EP-4181869-A1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A PHOSPHORIC ACID ESTER AND A DYEING COMPOUND Henkel AG & Co. KGaA (DE) 2023-05-24 EP disclosed
WO-2023041284-A1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, AN AMINO ACID, A DYEING COMPOUND AND A POST-TREATMENT AGENT HENKEL AG & CO. KGAA (DE) 2023-03-23 WO disclosed
US-11559557-B2 Medicament comprising ginger root CO2 extract SYMRISE AG (DE) 2023-01-24 US disclosed
EP-4117611-A1 METHOD FOR DYEING KERATIN MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, TWO DYEING COMPOUNDS AND A POST-TREATMENT AGENT Henkel AG & Co. KGaA (DE) 2023-01-18 EP disclosed
EP-3500238-B1 COLOR PROTECTION HAIR TREATMENT AGENT WITH EARTH ALKALINE SALTS OF DICARBOXYLIC ACIDS HENKEL AG & CO KGAA (DE) 2022-12-07 EP disclosed
US-20120204895-A1 HAIR TREATMENT AGENTS COMPRISING POLYQUATERNIUM-72 HENKEL AG & CO. KGAA (DE) 2012-08-16 US disclosed
US-20120128619-A1 COSMETIC AGENT HENKELSTRASSE 67 (DE) 2012-05-24 US disclosed
US-20090042169-A1 PREDOMINANTLY PLATELET-SHAPED, SPARINGLY WATER-SOLUBLE CALCIUM SALTS AND/OR COMPOSITE MATERIALS THEREOF COMPRISING THEM HENKEL AG & CO. KGAA (DE) 2009-02-12 US disclosed
US-20080226566-A1 USE OF POORLY WATER-SOLUBLE CALCIUM SALTS AND/OR THE COMPOSITES THEREOF HENKEL AG & CO. KGAA (DE) 2008-09-18 US disclosed
US-20070226917-A1 Hair Dye Agent Comprising Organosilicon Copolymers with Amino Groups and Polyoxyalkylene Groups and Use Thereof HENKEL KGAA (DE) 2007-10-04 US disclosed
US-7081140-B2 Developer components and their use for dyeing keratinic fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-07-25 US disclosed
US-20050198747-A1 Use of cationic starch derivatives for dye retention HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2005-09-15 US disclosed
US-20040255402-A1 Developer components and their use for dyeing keratinic fibers HENKEL AG & CO. KGAA (DE) 2004-12-23 US disclosed
US-6172018-B1 AQUEOUS CLEANING COMPOSITION COMPRISING ANIONIC SURFACTANT HAVING LIPOPHILIC GROUP AND POLAR GROUP, ALKYL GLYCOSIDE, ANIONIC POLYMER HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-01-09 US disclosed
US-5716418-A OXIDATION HAIR COLOR DYES; NONTOXIC, COLORFASTNESS, ABSORPTION, RECEPTIVITY HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1998-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120204895-A1 HAIR TREATMENT AGENTS COMPRISING POLYQUATERNIUM-72 HTT, AAAS, HNMT TSHR 1340/4885TDP1 1080/4885MAPT 420/4885
US-20040255402-A1 Developer components and their use for dyeing keratinic fibers KRT18, DSP, DSG1 TSHR 4883/4885TDP1 2712/4885MAPT 230/4885
US-11559557-B2 Medicament comprising ginger root CO2 extract CRY1, GRK1, GPER1 TSHR 2117/4885TDP1 4638/4885MAPT 1994/4885
US-20240000746-A1 New Cooling Agents and Preparations Containing Them TTPA, TREH, TAS2R45 TSHR 1885/4885TDP1 1359/4885MAPT 1054/4885
US-20120128619-A1 COSMETIC AGENT KRT18, PRKDC, POLR1C TSHR 3858/4885TDP1 1946/4885MAPT 2419/4885
US-20050198747-A1 Use of cationic starch derivatives for dye retention CUTA, GHDC, ALG1 TSHR 2594/4885TDP1 2272/4885MAPT 1329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.