Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18329148 | 0.85 | MEN1 (0.35) | ALDH1A1CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL28537993 | 0.80 | ALDH1A1 (0.35) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4637933 | 0.77 | TSHR (0.41) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL26192645 | 0.76 | ALDH1A1 (0.31) | ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1702497 | 0.75 | TSHR (0.38) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1001811 | 0.74 | TSHR (0.36) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8576089 | 0.73 | TSHR (0.37) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29192531 | 0.73 | TSHR (0.34) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28993157 | 0.72 | ALDH1A1 (0.32) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8524798 | 0.72 | TSHR (0.35) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605675-A | Synthesis of graphene oxide nano hydrogel plugging agent and water-based drilling fluid | 西南石油大学 | 2022-06-10 | — | — | CN | claimed |
| EP-3386476-A1 | COMPOSITION COMPRISING A POLYMER CONTAINING A SULFONIC MONOMER AND A PYRIDINEDICARBOXYLIC ACID DERIVATIVE, AND COSMETIC TREATMENT METHOD | L'Oréal (FR) | 2018-10-17 | — | — | EP | claimed |
| WO-2017097849-A1 | COMPOSITION COMPRISING A POLYMER CONTAINING A SULFONIC MONOMER AND A PYRIDINEDICARBOXYLIC ACID DERIVATIVE, AND COSMETIC TREATMENT METHOD | L'OREAL (FR) | 2017-06-15 | — | — | WO | claimed |
| US-7744858-B2 | Stable composition with high electrolyte content containing an amphiphilic polymer | L'OREAL (FR) | 2010-06-29 | — | — | US | claimed |
| US-20090053150-A1 | Aerosol device containing at least one amps polymer and at least one fixing polymer | L'OREAL S.A. (FR) | 2009-02-26 | — | — | US | claimed |
| EP-1353633-B1 | AMPHIPHILIC POLYMER-BASED PHOTOPROTECTIVE COMPOSITIONS | OREAL (FR) | 2008-05-28 | — | — | EP | claimed |
| EP-1361849-B1 | CLEANSING COMPOSITION CONTAINING AN AMPHIPHILIC POLYMER | OREAL (FR) | 2008-03-12 | — | — | EP | claimed |
| US-7338534-B2 | Oxidation dyeing composition for keratinous fibres based on amphiphilic polymers of at least an ethylenically unsaturated monomer with sulphonic group and comprising a hydrophobic part | L'OREAL (FR) | 2008-03-04 | — | — | US | claimed |
| US-20070104670-A1 | Cosmetic composition comprising at least one specific fixative polymer and at least one sulphonated polymer | L'OREAL S.A. (FR) | 2007-05-10 | — | — | US | claimed |
| EP-1302190-B1 | Cosmetic composition for make-up removal or skin cleansing | OREAL (FR) | 2006-12-20 | — | — | EP | claimed |
| US-6955803-B2 | Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers | L'OREAL (FR) | 2005-10-18 | — | — | US | claimed |
| US-20050086745-A1 | Oxidation dyeing composition for keratinous fibres on amphiphilic polymers of at least an ethylenically unsaturated monomer with sulphonic group and comprising a hydrophobic part | L'OREAL (FR) | 2005-04-28 | — | — | US | claimed |
| CN-1492753-A | Oxidizing composition for treating keratin materials, based on at least one ethylenically unsaturated monomer containing sulphonic groups and an amphiphilic polymer comprising hydrophobic portions | �ź㴫 | 2004-04-28 | — | — | CN | claimed |
| US-20040074015-A1 | Oxidising composition for treating keratinous materials based on amphiphilic polymers of at least an ethylenically unsaturated monomer containing a sulfonic group and comprising a hydrophobic part | L'OREAL (FR) | 2004-04-22 | — | — | US | claimed |
| US-20040071641-A1 | Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers | SOCIETE L'OREAL S.A. (FR) | 2004-04-15 | — | — | US | claimed |
| US-20040062728-A1 | Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers | SOCIETE L'OREAL, S.A. (FR) | 2004-04-01 | — | — | US | claimed |
| US-20030157047-A1 | Cosmetic composition for removing make-up from and clening the skin | L'OREAL (FR) | 2003-08-21 | — | — | US | claimed |
| US-20030108577-A1 | Cosmetic and/or dermatological acid composition containing an amphiphilic polymer | L'OREAL (FR) | 2003-06-12 | — | — | US | claimed |
| US-20030050201-A1 | Cleansing composition containing an amphiphilic polymer | L'OREAL (FR) | 2003-03-13 | — | — | US | claimed |
| US-20030036490-A1 | Stable composition with high electrolyte content containing an amphiphilic polymer | L'OREAL (FR) | 2003-02-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090053150-A1 | Aerosol device containing at least one amps polymer and at least one fixing polymer | POLR1C, PARN, CUTA | TSHR 3145/4885ALDH1A1 3395/4885CYP3A4 4859/4885 |
| US-20030157047-A1 | Cosmetic composition for removing make-up from and clening the skin | CUTA, DEGS1, LAGE3 | TSHR 3898/4885ALDH1A1 1947/4885CYP3A4 4736/4885 |
| US-20050086745-A1 | Oxidation dyeing composition for keratinous fibres on amphiphilic polymers of at least an ethylenically unsaturated monomer with sulphonic group and comprising a hydrophobic part | KRT18, ELOVL5, DSG1 | TSHR 4743/4885ALDH1A1 740/4885CYP3A4 1089/4885 |
| US-20040062728-A1 | Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers | CUTA, PCNA, DSG1 | TSHR 4532/4885ALDH1A1 1614/4885CYP3A4 3640/4885 |
| US-20040071641-A1 | Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers | CUTA, DSG1, PCNA | TSHR 3779/4885ALDH1A1 2367/4885CYP3A4 4197/4885 |
| US-20070104670-A1 | Cosmetic composition comprising at least one specific fixative polymer and at least one sulphonated polymer | KRT18, CUTA, ACR | TSHR 4028/4885ALDH1A1 375/4885CYP3A4 4552/4885 |
| US-20030108577-A1 | Cosmetic and/or dermatological acid composition containing an amphiphilic polymer | KRT18, DSG1, CUTA | TSHR 3699/4885ALDH1A1 1813/4885CYP3A4 4791/4885 |
| US-20030036490-A1 | Stable composition with high electrolyte content containing an amphiphilic polymer | KRT18, DSG1, SCNN1A | TSHR 3246/4885ALDH1A1 3241/4885CYP3A4 4796/4885 |
| US-20040074015-A1 | Oxidising composition for treating keratinous materials based on amphiphilic polymers of at least an ethylenically unsaturated monomer containing a sulfonic group and comprising a hydrophobic part | KRT18, DSG1, CUTA | TSHR 4775/4885ALDH1A1 1273/4885CYP3A4 2145/4885 |
| US-20030050201-A1 | Cleansing composition containing an amphiphilic polymer | UGCG, SGMS1, SGMS2 | TSHR 3829/4885ALDH1A1 2273/4885CYP3A4 4012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.