SCHEMBL4567366

SCHEMBL4567366

Cc1nc2ccc3ccccc3c2s1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
MAPT P10636 2/20 0.59
HPGD P15428 1/20 0.59
RAB9A P51151 4/20 0.53
NPC1 O15118 2/20 0.53
TLR8 Q9NR97 1/20 0.47
TLR7 Q9NYK1 1/20 0.47
CDK1 P06493 1/20 0.46
CDK4 P11802 1/20 0.46
CCNB1 P14635 1/20 0.46
CCND1 P24385 1/20 0.46
CCNE1 P24864 1/20 0.46
CDK2 P24941 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.42
HSD17B10 Q99714 3/20 0.42
KDM4E B2RXH2 1/20 0.42
HTT P42858 1/20 0.42
CYP3A4 P08684 1/20 0.41
CYP2A6 P11509 4/20 0.41
TSHR P16473 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30503124 1.00 ALDH1A1 (0.59) ALDH1A1MAPTHPGDRAB9ANPC1
SCHEMBL17281453 0.81 RAB9A (0.72) ALDH1A1MAPTHPGDRAB9ANPC1
SCHEMBL20669009 0.79 RAB9A (0.70) ALDH1A1MAPTHPGDRAB9ANPC1
SCHEMBL18133621 0.79 RAB9A (0.70) ALDH1A1MAPTHPGDRAB9ANPC1
SCHEMBL15001036 0.79 RAB9A (0.57) ALDH1A1MAPTHPGDRAB9ANPC1
SCHEMBL23607006 0.78 ALDH1A1 (0.46) ALDH1A1MAPTHPGDRAB9ANPC1
SCHEMBL20673464 0.78 MAPT (0.44) ALDH1A1MAPTHPGDRAB9ANPC1
SCHEMBL16153614 0.78 RAB9A (0.54) ALDH1A1MAPTHPGDRAB9ANPC1
SCHEMBL6483920 0.77 ALDH1A1 (0.44) ALDH1A1MAPTHPGDRAB9ANPC1
SCHEMBL7905037 0.77 CYP3A4 (0.41) ALDH1A1MAPTHPGDRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11829036-B2 Optically anisotropic multilayer product and method for producing same ZEON CORPORATION (JP) 2023-11-28 US disclosed
US-20230025656-A1 TRIARYLAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF CHANGCHUN HYPERIONS TECH CO LTD (CN) 2023-01-26 US disclosed
US-20220209132-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Changchun Hyperions Technology Co., Ltd. (CN) 2022-06-30 US disclosed
EP-3674757-B1 POLYMERIZABLE LIQUID CRYSTAL MATERIAL, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER, OPTICAL FILM, OPTICAL ANISOTROPIC BODY, POLARIZER, ANTIREFLECTIVE FILM, DISPLAY DEVICE AND METHOD FOR MANUFACTURING POLYMERIZABLE LIQUID CRYSTAL COMPOSITION ZEON CORP (JP) 2022-04-20 EP disclosed
US-20210214614-A1 LIQUID CRYSTAL CURED LAYER, PRODUCTION METHOD THEREFOR, OPTICAL FILM, POLARIZING PLATE, AND DISPLAY DEVICE ZEON CORPORATION (JP) 2021-07-15 US disclosed
WO-2021131856-A1 LIQUID CRYSTALLINE COMPOUND PRODUCTION METHOD 日本ゼオン株式会社 2021-07-01 WO disclosed
WO-2020137529-A1 RETARDATION FILM, METHOD FOR PRODUCING SAME AND POLARIZING PLATE 日本ゼオン株式会社 2020-07-02 WO disclosed
EP-3674757-A1 POLYMERIZABLE LIQUID CRYSTAL MATERIAL, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER, OPTICAL FILM, OPTICAL ANISOTROPIC BODY, POLARIZER, ANTIREFLECTIVE FILM, DISPLAY DEVICE AND METHOD FOR MANUFACTURING POLYMERIZABLE LIQUID CRYSTAL COMPOSITION Zeon Corporation (JP) 2020-07-01 EP disclosed
US-10647662-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2020-05-12 US disclosed
WO-2020045094-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL CURED FILM, POLARIZATION PLATE, ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE, AND LIQUID CRYSTAL CURED FILM PRODUCTION METHOD 日本ゼオン株式会社 2020-03-05 WO disclosed
WO-2002060374-A2 BENZ-1,3-AZOLE DERIVATIVES AND THEIR USES AS HEPARANASE INHIBITORS INSIGHT STRATEGY AND MARKETING LTD (IL) 2002-08-08 WO disclosed
EP-1223197-A2 Symmetric, monofunctionalised polymethine dyes labelling reagents Innosense S.r.l. (IT) 2002-07-17 EP disclosed
EP-1221465-A1 Symmetric, monofunctionalised polymethine dyes labelling reagents Innosense S.r.l. (IT) 2002-07-10 EP disclosed
EP-0565121-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1999-07-14 EP disclosed
EP-0772607-A1 WATER-SOLUBLE METHINE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER COMPRISING THE SAME FUJI PHOTO FILM CO., LTD. (JP) 1997-05-14 EP disclosed
US-5599825-A ANTITUMOR AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1997-02-04 US disclosed
US-5559240-A METHINE AND THIAZOLE DYES; STORAGE STABILITY; DISCOLORATION INHIBITION FUJI PHOTO FILM CO., LTD. (JP) 1996-09-24 US disclosed
WO-1996003393-A1 WATER-SOLUBLE METHINE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER COMPRISING THE SAME FUJI PHOTO FILM CO., LTD. (JP) 1996-02-08 WO disclosed
US-5397693-A Methine dyes FUJI PHOTO FILM CO., LTD. (JP) 1995-03-14 US disclosed
EP-0565121-A1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1993-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10647662-B2 Polymerizable compound and optically anisotropic body RCC1, SMC4, SMCHD1 ALDH1A1 4138/4885MAPT 43/4885HPGD 4355/4885
US-20230025656-A1 TRIARYLAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF TRDMT1, TCF4, TRMT1 ALDH1A1 1764/4885MAPT 647/4885HPGD 4726/4885
US-20220209132-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME EML4, STOM, GJB2 ALDH1A1 2548/4885MAPT 553/4885HPGD 2011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.