SCHEMBL457605

SCHEMBL457605

CCCCCCCCCCCCCCCCCC(=O)C(CNCCO)C(=O)CCCCCCCCCCCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 1/20 0.47
▸ MEN1 O00255 1/20 0.44
▸ FAAH O00519 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ NAAA Q02083 1/20 0.43
▸ SELP P16109 1/20 0.42
▸ CNR1 P21554 1/20 0.41
▸ CNR2 P34972 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL455074 1.00 CES2 (0.47) CES2MEN1FAAHMAPK1KMT2A
Hydrochloric Acid SCHEMBL16538160 0.98 CES2 (0.46) CES2MEN1FAAHMAPK1KMT2A
Sulfuric Acid SCHEMBL29052907 0.94 NAAA (0.42) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL5846756 0.94 NAAA (0.42) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL28363750 0.89 CA12 (0.40) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL19409849 0.89 CA12 (0.40) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL5907430 0.86 CES2 (0.50) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL115278 0.85 CES2 (0.46) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL10790207 0.85 CES2 (0.46) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL29174031 0.85 CES2 (0.46) CES2MEN1FAAHMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4060054-B1 PRODUCTS FOR THE TANNING OF LEATHERS, PRE-TANNING PRODUCTS AND USE THEREOF SILVATEAM S P A (IT) 2023-11-15 — — EP claimed
EP-2677990-B1 COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A DIRECT DYE BEARING A DISULFIDE/THIOL FUNCTION, A SPARINGLY OR NON-ETHOXYLATED FATTY ALCOHOL, A CATIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT OREAL (FR) 2019-05-15 — — EP claimed
US-20260137607-A1 COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND A FATTY ACID ESTER OF GLYCEROL LOREAL (FR) 2026-05-21 — — US disclosed
US-12622853-B2 Composition comprising a particular oxidation dye precursor and a particular amino silicone L'OREAL (FR) 2026-05-12 — — US disclosed
EP-4262720-B1 COMPOSITION COMPRISING TWO PARTICULAR OXIDATION DYE PRECURSORS, AND A PARTICULAR CARBOXYLIC ACID OREAL (FR) 2026-05-06 — — EP disclosed
EP-4262716-B1 COMPOSITION COMPRISING A PARTICULAR OXIDATION DYE PRECURSOR AND A PARTICULAR CARBOXYLIC ACID OREAL (FR) 2026-05-06 — — EP disclosed
EP-4262691-B1 COSMETIC COMPOSITION COMPRISING A COMBINATION OF TWO PARTICULAR COUPLERS AND N,N-DICARBOXYMETHYLGLUTAMIC ACID AND/OR ITS SALTS OREAL (FR) 2026-04-08 — — EP disclosed
EP-4262689-B1 COMPOSITION COMPRISING A PARTICULAR OXIDATION DYEING BASE, AT LEAST ONE GUAR GUM AND AT LEAST ONE FATTY SUBSTANCE OREAL (FR) 2026-04-08 — — EP disclosed
US-12589063-B2 Composition comprising a combination of two particular oxidation dye precursors, an amphoteric or zwitterionic surfactant and a solid fatty substance L'OREAL (FR) 2026-03-31 — — US disclosed
US-12569420-B2 Composition comprising a particular oxidation dyeing base and at least two particular couplers L'ORÉAL (FR) 2026-03-10 — — US disclosed
US-12558301-B2 Composition comprising a particular oxidation dye precursor and a particular amino silicone L'ORÉAL (FR) 2026-02-24 — — US disclosed
WO-2012032055-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE CATIONIC POLYMER AND AT LEAST TWO CATIONIC SURFACTANTS L'OREAL (FR) 2012-03-15 — — WO disclosed
WO-2011117403-A2 COMPOSITION COMPRISING A SILICONE COPOLYMER, A SILICONE SURFACTANT AND A NON-VOLATILE PDMS, COSMETIC TREATMENT METHOD AND USE. L'ORÉAL (FR) 2011-09-29 — — WO disclosed
US-20110168200-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE TYPE OF HOLLOW PARTICLE, AT LEAST ONE STARCH AND AT LEAST ONE CATIONIC SURFACTANT L'OREAL S.A (FR) 2011-07-14 — — US disclosed
EP-2338468-A1 Cosmetic composition comprising at least one volatile linear alkane, at least one cationic surfactant whereby the two components are in a specific ratio L'Oréal (FR) 2011-06-29 — — EP disclosed
EP-2338469-A1 Use of a cosmetic composition containing a linear volatile alcane and an associative non-ionic polymer for conditioning the hair L'Oréal (FR) 2011-06-29 — — EP disclosed
EP-2322136-A1 Cosmetic hair-conditioner composition containing a mixture of hollow particles, starch and a cationic surfactant L'Oréal (FR) 2011-05-18 — — EP disclosed
EP-2322135-A1 Cosmetic composition including a structuring agent, an absorbent agent and a surfactant for application to keratin materials L'Oréal (FR) 2011-05-18 — — EP disclosed
US-20090123397-A1 Microbiocidal compositions THOR SPECIALITIES (UK) LIMITED (GB) 2009-05-14 — — US disclosed
EP-2000122-A2 Microbiocidal composition Thor Specialities (UK) Lmited (GB) 2008-12-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12589063-B2 Composition comprising a combination of two particular oxidation dye precursors, an amphoteric or zwitterionic surfactant and a solid fatty substance S100P, KRT18, S100A4 CES2 1530/4885MEN1 4703/4885FAAH 620/4885
US-12558301-B2 Composition comprising a particular oxidation dye precursor and a particular amino silicone KRT18, PLOD1, PLOD2 CES2 1159/4885MEN1 4086/4885FAAH 3699/4885
US-12569420-B2 Composition comprising a particular oxidation dyeing base and at least two particular couplers KRT18, COL1A1, S100P CES2 2373/4885MEN1 3700/4885FAAH 690/4885
US-20260137607-A1 COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND A FATTY ACID ESTER OF GLYCEROL KRT18, FABP4, HSD17B4 CES2 1148/4885MEN1 3732/4885FAAH 175/4885
US-12622853-B2 Composition comprising a particular oxidation dye precursor and a particular amino silicone KRT18, SCNN1B, PLOD3 CES2 2407/4885MEN1 4277/4885FAAH 3146/4885
US-20110168200-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE TYPE OF HOLLOW PARTICLE, AT LEAST ONE STARCH AND AT LEAST ONE CATIONIC SURFACTANT SGMS1, LIPA, SGMS2 CES2 829/4885MEN1 334/4885FAAH 1113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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