SCHEMBL4585365

SCHEMBL4585365

FC(F)(F)c1ccccc1-c1oc(-c2ccccc2C(F)(F)F)c2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
C1R P00736 1/20 0.49
NOTUM Q6P988 2/20 0.45
PSMB8 P28062 1/20 0.45
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HSD11B1 P28845 1/20 0.43
NPFFR1 Q9GZQ6 2/20 0.42
NPFFR2 Q9Y5X5 2/20 0.42
LMNA P02545 2/20 0.42
SLC9A1 P19634 1/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29555487 1.00 C1R (0.49) C1RNOTUMPSMB8ALDH1A1HPGD
SCHEMBL197671 0.77 HSD11B1 (0.56) NOTUMPSMB8ALDH1A1HPGDHSD11B1
SCHEMBL8022901 0.74 HSD11B1 (0.54) NOTUMPSMB8ALDH1A1HPGDHSD11B1
Hydrochloric Acid SCHEMBL29010139 0.74 HSD11B1 (0.54) NOTUMPSMB8ALDH1A1HPGDHSD11B1
SCHEMBL27591664 0.71 LMNA (0.49) NOTUMPSMB8ALDH1A1HPGDMAPT
SCHEMBL10028048 0.71 SMN1; SMN2 (0.51) PSMB8ALDH1A1HPGDMAPTHTT
SCHEMBL22304414 0.70 AR (0.58) NOTUMALDH1A1HSD11B1CYP1A2CYP2D6
SCHEMBL23567431 0.69 HSD11B1 (0.46) NOTUMPSMB8ALDH1A1HSD11B1CYP1A2
SCHEMBL16401280 0.69 NOTUM (0.44) C1RNOTUMPSMB8ALDH1A1HPGD
SCHEMBL17798997 0.69 AR (0.44) C1RNOTUMPSMB8ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080034-A Polycyclic aromatic compound and organic electroluminescent element 2026-05-26 CN disclosed
CN-122059973-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 爱思开新材料捷恩智株式会社 2026-05-19 CN disclosed
EP-4663642-A1 POLYCYCLIC AROMATIC COMPOUND Kyoto University (JP) 2025-12-17 EP disclosed
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
CN-120157693-A Polycyclic aromatic compound and organic electroluminescent element 爱思开新材料捷恩智株式会社 2025-06-17 CN disclosed
CN-120118107-A Polycyclic aromatic compound and organic electroluminescent element 爱思开新材料捷恩智株式会社 2025-06-10 CN disclosed
CN-120040479-A Polycyclic aromatic compound and organic electroluminescent element 爱思开新材料捷恩智株式会社 2025-05-27 CN disclosed
CN-119930662-A Polycyclic aromatic compound, organic electroluminescent element, display device, and lighting device 爱思开新材料捷恩智株式会社 2025-05-06 CN disclosed
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-03-06 US disclosed
CN-119504805-A Polycyclic aromatic compound, organic electroluminescent element, and display device or lighting device 国立大学法人京都大学 2025-02-25 CN disclosed
US-20140319510-A1 BENZOFLUORENE COMPOUND, MATERIAL FOR LUMINESCENT LAYER USING SAID COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE JNC CORPORATION (JP) 2014-10-30 US disclosed
EP-2784057-A1 BENZOFLUORENE COMPOUND, MATERIAL FOR LUMINESCENT LAYER USING SAID COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE JNC Corporation (JP) 2014-10-01 EP disclosed
US-20130292665-A1 NOVEL ANTHRACENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC CORPORATION (JP) 2013-11-07 US disclosed
US-20130134405-A1 BENZOFLUORENE COMPOUND, EMISSION MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE JNC CORPORATION (JP) 2013-05-30 US disclosed
CN-102639525-A Benzo[c]carbazole compound that has substituent bearing pyridine ring, and organic electroluminescent element JNC CORP 2012-08-15 CN disclosed
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device JNC CORPORATION (JP) 2008-07-03 US disclosed
US-20080105865-A1 Pyrene Based Compound and Light Emitting Transistor Element Using the Same PIONEER CORPORATION (JP) 2008-05-08 US disclosed
US-20080012475-A1 Pyrene Based Compound, And Light Emitting Transistor Element And Electroluminescence Element Using The Same MITSUBISHI CHEMICAL CORPORATION (JP) 2008-01-17 US disclosed
EP-1818322-A1 PYRENE COMPOUND AND, UTILIZING THE SAME, LIGHT EMITTING TRANSISTOR DEVICE AND ELECTROLUMINESCENCE DEVICE Rohm Co., Ltd. (JP) 2007-08-15 EP disclosed
EP-1816114-A1 PYRENE COMPOUND AND LIGHT EMITTING TRANSISTOR DEVICE UTILIZING THE SAME Rohm Co., Ltd. (JP) 2007-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device LEF1, TRPA1, BRD8 C1R 3934/4885NOTUM 1586/4885PSMB8 2529/4885
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 C1R 4231/4885NOTUM 3408/4885PSMB8 3576/4885
US-20080105865-A1 Pyrene Based Compound and Light Emitting Transistor Element Using the Same CYP1A1, SULT1A1, SULT1E1 C1R 794/4885NOTUM 1661/4885PSMB8 2257/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 C1R 4231/4885NOTUM 3408/4885PSMB8 3576/4885
US-20080012475-A1 Pyrene Based Compound, And Light Emitting Transistor Element And Electroluminescence Element Using The Same ARNT, ESR1, TEAD4 C1R 4370/4885NOTUM 1134/4885PSMB8 4044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.