Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.88 |
| ▸ | TTPA | P49638 | 3/20 | 0.88 |
| ▸ | MAPT | P10636 | 2/20 | 0.88 |
| ▸ | MEN1 | O00255 | 2/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.88 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.88 |
| ▸ | USP2 | O75604 | 1/20 | 0.88 |
| ▸ | THRB | P10828 | 1/20 | 0.88 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.88 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.88 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.83 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.83 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.69 |
| ▸ | PDE4A | P27815 | 1/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.68 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.66 |
| ▸ | AKT1 | P31749 | 2/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | PHLPP1 | O60346 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alpha-Tocopherol SCHEMBL28174565 | 0.95 | LMNA (0.89) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tochopherol SCHEMBL1879635 | 0.95 | LMNA (0.89) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL27538180 | 0.95 | LMNA (0.89) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL27177 | 0.95 | LMNA (0.89) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL4083978 | 0.95 | LMNA (0.89) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL27696980 | 0.95 | LMNA (0.89) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL28174566 | 0.95 | LMNA (0.89) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL27790585 | 0.94 | LMNA (0.84) | LMNATTPAMAPTMEN1KMT2A | |
| Alpha-Tocopherol SCHEMBL5868266 | 0.94 | LMNA (0.88) | LMNATTPAMAPTMEN1KMT2A | |
| SCHEMBL8084077 | 0.94 | LMNA (1.00) | LMNATTPAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545407-A | ANTIACNE AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1996-08-13 | — | — | US | claimed |
| US-20170105967-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF INFLAMMATORY SKIN CONDITIONS USING ALLANTOIN | SCIODERM, INC. (US) | 2017-04-20 | — | — | US | disclosed |
| US-20170105968-A1 | Compositions and Methods for Treatment of Inflammatory Skin Conditions Using Allantoin | SCIODERM, INC. (US) | 2017-04-20 | — | — | US | disclosed |
| US-20170049749-A1 | METHODS FOR TREATING BURNS USING ALLANTOIN | Scioderm.Inc. (US) | 2017-02-23 | — | — | US | disclosed |
| EP-3104858-A1 | METHODS FOR TREATING BURNS USING ALLANTOIN | Scioderm Inc. (US) | 2016-12-21 | — | — | EP | disclosed |
| US-20160338997-A1 | KELOID REDUCTION USING TOPICAL ALLANTOIN | SCIODERM, INC. (US) | 2016-11-24 | — | — | US | disclosed |
| EP-3089729-A1 | ALLANTOIN COMPOSITIONS FOR TREATING INFLAMMATORY SKIN CONDITIONS | Scioderm Inc. (US) | 2016-11-09 | — | — | EP | disclosed |
| EP-3086786-A1 | KELOID REDUCTION USING TOPICAL ALLANTOIN | Scioderm Inc. (US) | 2016-11-02 | — | — | EP | disclosed |
| US-20160213649-A1 | Compositions And Methods Of Treatment Of Inflammatory Skin Conditions Using Allantoin | SCIODERM, INC. (US) | 2016-07-28 | — | — | US | disclosed |
| US-9339492-B1 | Methods of treating psoriasis using allantoin | SCIODERM, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| WO-2003041688-A1 | METHODS FOR TREATMENT OF INFLAMMATORY DISEASES | ALWYN COMPANY, INC. (US) | 2003-05-22 | — | — | WO | disclosed |
| WO-2003041651-A2 | ALLATOIN-CONTAINING SKIN CREAM | ALWYN COMPANY, INC. (US) | 2003-05-22 | — | — | WO | disclosed |
| US-20020054895-A1 | And at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water; skin protectants | ALWYN COMPANY, INC. | 2002-05-09 | — | — | US | disclosed |
| US-20020055531-A1 | Methods for treatment of inflammatory diseases | SWEEN, MAURICE ALWYN | 2002-05-09 | — | — | US | disclosed |
| EP-0787005-B1 | DERMATOLOGICAL COMPOSITIONS CONTAINING BENZOYL PEROXIDE AND A COMPOUND REDUCING SKIN IRRITATION | HERMAL KURT HERRMAN GMBH (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-5932228-A | ADMINISTERING BENZOYL PEROXIDE AND COMPOUND THAT REDUCES SKIN IRRITATION | THE PROCTER & GAMBLE COMPANY (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0787005-A2 | DERMATOLOGICAL COMPOSITIONS CONTAINING BENZOYL PEROXIDE AND A COMPOUND REDUCING SKIN IRRITATION | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-06 | — | — | EP | disclosed |
| US-5545407-A | ANTIACNE AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1996012498-A2 | DERMATOLOGICAL COMPOSITIONS CONTAINING BENZOYL PEROXIDE AND A COMPOUND REDUCING SKIN IRRITATION | THE PROCTER & GAMBLE COMPANY (US) | 1996-05-02 | — | — | WO | disclosed |
| US-5445823-A | Benzoyl peroxide and a compound for reducing skin irritation associated with it | THE PROCTER & GAMBLE COMPANY (US) | 1995-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170049749-A1 | METHODS FOR TREATING BURNS USING ALLANTOIN | ALKBH1, ALKBH3, FAAH2 | LMNA 1865/4885TTPA 959/4885MAPT 4448/4885 |
| US-20170105967-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF INFLAMMATORY SKIN CONDITIONS USING ALLANTOIN | CUTA, ITCH, ARG1 | LMNA 897/4885TTPA 1351/4885MAPT 3089/4885 |
| US-20160213649-A1 | Compositions And Methods Of Treatment Of Inflammatory Skin Conditions Using Allantoin | CUTA, ITCH, ARG1 | LMNA 897/4885TTPA 1351/4885MAPT 3089/4885 |
| US-20160338997-A1 | KELOID REDUCTION USING TOPICAL ALLANTOIN | AADAT, NOTUM, ALOX15 | LMNA 1451/4885TTPA 441/4885MAPT 4119/4885 |
| US-20170105968-A1 | Compositions and Methods for Treatment of Inflammatory Skin Conditions Using Allantoin | CUTA, ITCH, ARG1 | LMNA 953/4885TTPA 1447/4885MAPT 3039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.