Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106215 | 0.82 | KIF11 (0.63) | KIF11 | |
| SCHEMBL4613838 | 0.75 | KIF11 (0.72) | KIF11 | |
| SCHEMBL18599373 | 0.73 | KIF11 (0.57) | KIF11 | |
| SCHEMBL26224 | 0.72 | KIF11 (0.55) | KIF11 | |
| SCHEMBL6909006 | 0.72 | KIF11 (0.55) | KIF11 | |
| SCHEMBL28183597 | 0.70 | HSD11B1 (0.39) | KIF11 | |
| SCHEMBL13741458 | 0.70 | KIF11 (0.74) | KIF11 | |
| SCHEMBL14229524 | 0.70 | KCNN4 (0.47) | KIF11 | |
| Ethyl(Trityl)Sulfane SCHEMBL4755270 | 0.69 | KIF11 (0.56) | KIF11 | |
| SCHEMBL27656875 | 0.69 | KCNN4 (0.44) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1905904-B | Novel imaging agents comprising caspase-3 inhibitors | GE HEALTHCARE LTD. (GB) | 2011-12-21 | — | — | CN | disclosed |
| US-20080279769-A1 | Enzyme Inhibitor Imaging Agents | SOLBAKKEN MAGNE | 2008-11-13 | — | — | US | disclosed |
| CN-101155602-A | Imaging agents comprising caspase-3 substrates | GE HEALTHCARE LTD (GB) | 2008-04-02 | — | — | CN | disclosed |
| EP-1682113-B1 | INHIBITOR IMAGING AGENTS | GE HEALTHCARE LTD (GB) | 2008-01-23 | — | — | EP | disclosed |
| EP-1853324-A1 | CASPASE-3 SUBSTRATE COMPRISING IMAGING AGENTS | GE Healthcare Limited (GB) | 2007-11-14 | — | — | EP | disclosed |
| EP-1796736-A2 | METALLOPROTEINASE INHIBITOR IMAGING AGENTS | GE Healthcare Limited (GB) | 2007-06-20 | — | — | EP | disclosed |
| US-20070104644-A1 | Inhibitor imaging agents | CUTHBERTSON ALAN | 2007-05-10 | — | — | US | disclosed |
| EP-1763371-A2 | NOVEL IMAGING AGENTS COMPRISING CASPASE-3 INHIBITORS | GE Healthcare Limited (GB) | 2007-03-21 | — | — | EP | disclosed |
| CN-1905904-A | Novel imaging agents comprising caspase-3 inhibitors | GE HEALTHCARE LTD (GB) | 2007-01-31 | — | — | CN | disclosed |
| WO-2006082434-A1 | CASPASE-3 SUBSTRATE COMPRISING IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2006-08-10 | — | — | WO | disclosed |
| EP-1682113-A1 | INHIBITOR IMAGING AGENTS | GE Healthcare Limited (GB) | 2006-07-26 | — | — | EP | disclosed |
| US-20060120956-A1 | Imaging agents comprising barbituric acid derivatives | KOPKA KLAUS | 2006-06-08 | — | — | US | disclosed |
| WO-2006032911-A2 | METALLOPROTEINASE INHIBITOR IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2006-03-30 | — | — | WO | disclosed |
| CN-1720050-A | Improved imaging agents comprising barbituric acid derivatives | AMERSHAM PLC (GB) | 2006-01-11 | — | — | CN | disclosed |
| WO-2005053752-A2 | NOVEL IMAGING AGENTS COMPRISING CASPASE-3 INHIBITORS | GE HEALTHCARE LIMITED (GB) | 2005-06-16 | — | — | WO | disclosed |
| WO-2005049005-A1 | INHIBITOR IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2005-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060120956-A1 | Imaging agents comprising barbituric acid derivatives | CA5A, GABRA5, CA5B | KIF11 2446/4885 |
| US-20080279769-A1 | Enzyme Inhibitor Imaging Agents | MMP3, MMP1, MMP10 | KIF11 2407/4885 |
| US-20070104644-A1 | Inhibitor imaging agents | MMP3, MMP1, MMP10 | KIF11 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.