Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1938661 | 0.92 | ALDH1A1 (0.47) | ALDH1A1CA4KDM4ELMNAMAPT | |
| SCHEMBL8842951 | 0.92 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAMAPTALOX15 | |
| SCHEMBL28065364 | 0.92 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAMAPTALOX15 | |
| Citric Acid SCHEMBL7055559 | 0.91 | CA4 (0.49) | ALDH1A1CA4 | |
| SCHEMBL149815 | 0.90 | ALDH1A1 (0.48) | ALDH1A1CA4KDM4ELMNAMAPT | |
| SCHEMBL28168350 | 0.90 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNAMAPTALOX15 | |
| Water SCHEMBL28198147 | 0.90 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNAMAPTALOX15 | |
| SCHEMBL23054 | 0.90 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNAMAPTALOX15 | |
| Citric Acid SCHEMBL12481970 | 0.90 | CA4 (0.47) | ALDH1A1CA4 | |
| SCHEMBL7121071 | 0.89 | CA4 (0.53) | ALDH1A1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125399-B2 | Method of employing enhanced penetration of wood preservatives to protect wood and a related solution | KOP-COAT, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-9125398-B2 | Method of employing enhanced penetration of wood preservatives to protect wood and a related solution | KOP-COAT, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-20140039016-A1 | METHOD OF EMPLOYING ENHANCED PENETRATION OF WOOD PRESERVATIVES TO PROTECT WOOD AND A RELATED SOLUTION | KOP-COAT, INC. | 2014-02-06 | — | — | US | disclosed |
| US-20120258248-A1 | METHOD OF EMPLOYING ENHANCED PENETRATION OF WOOD PRESERVATIVES TO PROTECT WOOD AND A RELATED SOLUTION | KOP-COAT, INC. | 2012-10-11 | — | — | US | disclosed |
| EP-1880732-A1 | Parathyroid hormone formulation | NPS Allelix Corp. (CA) | 2008-01-23 | — | — | EP | disclosed |
| EP-0735896-B1 | PARATHYROID HORMONE FORMULATION | NPS ALLELIX CORP (CA) | 2007-10-03 | — | — | EP | disclosed |
| US-5653917-A | Rust-removing alkali metal hydrogen citrate composition | SINGERMAN GARY M (US) | 1997-08-05 | — | — | US | disclosed |
| EP-0735896-A1 | PARATHYROID HORMONE FORMULATION | Astra Aktiebolag (SE) | 1996-10-09 | — | — | EP | disclosed |
| US-5496801-A | Parathyroid hormone formulation | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1996-03-05 | — | — | US | disclosed |
| WO-1995017207-A1 | PARATHYROID HORMONE FORMULATION | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1995-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140039016-A1 | METHOD OF EMPLOYING ENHANCED PENETRATION OF WOOD PRESERVATIVES TO PROTECT WOOD AND A RELATED SOLUTION | AOC3, CMA1, AGER | CA4 228/4885ALDH1A1 777/4885KDM4E 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.