Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900020 | 0.82 | APP (0.39) | CA12CA1CA2CA4CA7 | |
| SCHEMBL2092104 | 0.81 | CA12 (0.62) | CA12CA1CA2CA4CA7 | |
| SCHEMBL11837900 | 0.81 | ALDH1A1 (0.56) | L3MBTL1TDP1CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL6721783 | 0.80 | L3MBTL1 (0.61) | CA12CA1CA2CA4CA7 | |
| SCHEMBL1592409 | 0.80 | CA12 (0.68) | CA12CA1CA2CA4CA7 | |
| SCHEMBL11364617 | 0.80 | CA1 (0.68) | CA12CA1CA2CA4CA7 | |
| 1,2-Dimethoxybenzene SCHEMBL29351917 | 0.79 | CA1 (1.00) | CA12CA1CA2CA4CA7 | |
| 1,2-Dimethoxybenzene SCHEMBL105872 | 0.79 | CA1 (1.00) | CA12CA1CA2CA4CA7 | |
| 1,2-Dimethoxybenzene SCHEMBL5308636 | 0.79 | CA1 (1.00) | CA12CA1CA2CA4CA7 | |
| SCHEMBL6721575 | 0.79 | L3MBTL1 (0.65) | CA12CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2024-01-25 | — | — | US | disclosed |
| US-11858931-B2 | Amino acid compounds with unbranched linkers and methods of use | PLIANT THERAPEUTICS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-11834455-B2 | Carm1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| EP-3160462-B1 | LEOLIGIN DERIVATIVES AS PROLIFERATION INHIBITORS OF SMOOTH MUSCLE CELLS | UNIV WIEN TECH (AT) | 2023-11-22 | — | — | EP | disclosed |
| EP-4265602-A2 | LEOLIGIN DERIVATIVES AS PROLIFERATION INHIBITORS OF SMOOTH MUSCLE CELLS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2023-10-25 | — | — | EP | disclosed |
| US-20230279020-A9 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2023-09-07 | — | — | US | disclosed |
| US-20230234970-A1 | IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
| US-11634421-B2 | Aryl substituted bicyclic compounds as herbicides | FMC CORPORATION (US) | 2023-04-25 | — | — | US | disclosed |
| US-11357230-B2 | Herbicidal amides | FMC CORPORATION (US) | 2022-06-14 | — | — | US | disclosed |
| US-20180077931-A1 | BUTYROLACTONES AS HERBICIDES | FMC CORPORATION | 2018-03-22 | — | — | US | disclosed |
| US-20180057442-A1 | 3-OXO-3-(ARYLAMINO)PROPANOATES, A PROCESS FOR THEIR PREPARATION, AND THEIR USE IN PREPARING PYRROLIDINONES | FMC CORPORATION | 2018-03-01 | — | — | US | disclosed |
| US-20180037564-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC CORPORATION | 2018-02-08 | — | — | US | disclosed |
| US-9738651-B2 | CARM1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-08-22 | — | — | US | disclosed |
| US-20170158638-A1 | PIPERIDINONE HERBICIDES | FMC CORPORATION | 2017-06-08 | — | — | US | disclosed |
| US-20170056409-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-03-02 | — | — | US | disclosed |
| EP-1960518-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007067559-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-06-14 | — | — | WO | disclosed |
| EP-1278728-A1 | PYRROLIDINE AND PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001081303-A1 | PYRROLIDINE AND PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREAMENT OF NEURODEGENERATIVE DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158638-A1 | PIPERIDINONE HERBICIDES | CYP1A1, CYP1B1, ARG1 | CA12 3778/4885CA1 1025/4885CA2 735/4885 |
| US-11357230-B2 | Herbicidal amides | CYP1A1, DDT, CYP1B1 | CA12 2827/4885CA1 559/4885CA2 517/4885 |
| US-20180077931-A1 | BUTYROLACTONES AS HERBICIDES | CYP1B1, CYP1A1, DDT | CA12 3148/4885CA1 1305/4885CA2 675/4885 |
| US-20230279020-A9 | CARM1 INHIBITORS AND USES THEREOF | CARM1, TIAM1, ADRM1 | CA12 4169/4885CA1 3865/4885CA2 3725/4885 |
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | CA12 874/4885CA1 196/4885CA2 61/4885 |
| US-11834455-B2 | Carm1 inhibitors and uses thereof | CARM1, TIAM1, ADRM1 | CA12 4183/4885CA1 3881/4885CA2 3741/4885 |
| US-20230234970-A1 | IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CD274, PDCD1, PDCD1LG2 | CA12 4480/4885CA1 4711/4885CA2 4808/4885 |
| US-20180037564-A1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | CYP4X1, DDT, CHRM1 | CA12 1293/4885CA1 219/4885CA2 244/4885 |
| US-20170056409-A1 | CARM1 INHIBITORS AND USES THEREOF | CARM1, TIAM1, ADRM1 | CA12 4251/4885CA1 4030/4885CA2 3795/4885 |
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | F7, F11, HABP2 | CA12 2635/4885CA1 2437/4885CA2 2222/4885 |
| US-11634421-B2 | Aryl substituted bicyclic compounds as herbicides | CYP1B1, CYP1A1, CBR3 | CA12 3041/4885CA1 1215/4885CA2 776/4885 |
| US-11858931-B2 | Amino acid compounds with unbranched linkers and methods of use | ITGA2B, ITGB6, ITGB1 | CA12 3569/4885CA1 4313/4885CA2 4198/4885 |
| US-20180057442-A1 | 3-OXO-3-(ARYLAMINO)PROPANOATES, A PROCESS FOR THEIR PREPARATION, AND THEIR USE IN PREPARING PYRROLIDINONES | SDHA, SDHB, NDUFV3 | CA12 4045/4885CA1 3156/4885CA2 4309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.