Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.32 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.32 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28899359 | 0.89 | GMNN (0.52) | GMNNALDH1A1LMNATP53TSHR | |
| SCHEMBL27175717 | 0.86 | GMNN (0.50) | GMNNALDH1A1LMNATP53TSHR | |
| SCHEMBL3890653 | 0.86 | GMNN (0.50) | GMNNALDH1A1LMNATP53TSHR | |
| SCHEMBL29283222 | 0.78 | KDM4E (0.52) | GMNNALDH1A1LMNATP53TSHR | |
| SCHEMBL29283218 | 0.78 | KDM4E (0.52) | GMNNALDH1A1LMNATP53TSHR | |
| SCHEMBL14856462 | 0.77 | TDP1 (0.48) | TDP1LMNA | |
| SCHEMBL4772745 | 0.77 | GMNN (0.41) | GMNNALDH1A1LMNATP53TSHR | |
| SCHEMBL918188 | 0.76 | — | — | |
| SCHEMBL3424157 | 0.76 | ALDH1A1 (0.55) | GMNNALDH1A1LMNATP53TSHR | |
| SCHEMBL4662177 | 0.76 | TDP1 (0.46) | TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004404-B1 | COPPER ELECTROPLATING OF PRINTING CYLINDERS | MACDERMID INC (US) | 2013-04-17 | — | — | EP | claimed |
| EP-2004404-A2 | COPPER ELECTROPLATING OF PRINTING CYLINDERS | MacDermid, Incorporated (US) | 2008-12-24 | — | — | EP | claimed |
| WO-2007120365-A2 | COPPER ELECTROPLATING OF PRINTING CYLINDERS | MACDERMID, INCORPORATED (US) | 2007-10-25 | — | — | WO | claimed |
| US-7153408-B1 | Copper electroplating of printing cylinders | CITIBANK, N.A. | 2006-12-26 | — | — | US | claimed |
| EP-2004404-B1 | COPPER ELECTROPLATING OF PRINTING CYLINDERS | MACDERMID INC (US) | 2013-04-17 | — | — | EP | disclosed |
| EP-2004404-A2 | COPPER ELECTROPLATING OF PRINTING CYLINDERS | MacDermid, Incorporated (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007120365-A2 | COPPER ELECTROPLATING OF PRINTING CYLINDERS | MACDERMID, INCORPORATED (US) | 2007-10-25 | — | — | WO | disclosed |
| US-7153408-B1 | Copper electroplating of printing cylinders | CITIBANK, N.A. | 2006-12-26 | — | — | US | disclosed |