Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385164 | 0.93 | PYGL (0.38) | TSHRCNR2CNR1ALDH1A1LMNA | |
| SCHEMBL2137605 | 0.83 | TP53 (0.35) | CNR2CNR1ALDH1A1LMNAKMT2A | |
| SCHEMBL3086322 | 0.79 | DHODH (0.49) | DHODHMAPTSMN1; SMN2 | |
| SCHEMBL4769625 | 0.79 | CARM1 (0.42) | TP53DHODH | |
| SCHEMBL2138745 | 0.79 | L3MBTL1 (0.36) | CNR2ALDH1A1KMT2ATP53POLB | |
| SCHEMBL4151156 | 0.77 | RIPK1 (0.39) | CNR2CNR1ALDH1A1TP53HPGD | |
| SCHEMBL782468 | 0.76 | DHODH (0.41) | TSHRCNR2CNR1ALDH1A1DHODH | |
| SCHEMBL31256508 | 0.76 | DHODH (0.41) | TSHRCNR2CNR1ALDH1A1DHODH | |
| SCHEMBL4168983 | 0.74 | PDE4B (0.44) | ALDH1A1KMT2ATP53POLBMAPT | |
| SCHEMBL10028777 | 0.74 | DHODH (0.40) | ALDH1A1LMNAKMT2ADHODHPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265850-B1 | INSECTICIDAL ANTHRANILAMIDES | DU PONT (US) | 2007-01-03 | — | — | EP | claimed |
| US-20040142984-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2004-07-22 | — | — | US | claimed |
| US-6747047-B2 | ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-06-08 | — | — | US | claimed |
| US-20030229050-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2003-12-11 | — | — | US | claimed |
| EP-1700845-B1 | Insecticidal anthranilamides | DU PONT (US) | 2008-12-10 | — | — | EP | disclosed |
| US-7338978-B2 | Insecticidal anthranilamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| EP-1265850-B1 | INSECTICIDAL ANTHRANILAMIDES | DU PONT (US) | 2007-01-03 | — | — | EP | disclosed |
| EP-1700845-A1 | Insecticidal anthranilamides | E.I.Du pont de nemours and company (US) | 2006-09-13 | — | — | EP | disclosed |
| US-20060079561-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2006-04-13 | — | — | US | disclosed |
| US-6995178-B2 | Insecticidal anthranilamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-02-07 | — | — | US | disclosed |
| US-20040142984-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2004-07-22 | — | — | US | disclosed |
| US-6747047-B2 | ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-06-08 | — | — | US | disclosed |
| US-20030229050-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2003-12-11 | — | — | US | disclosed |
| EP-1265850-A2 | INSECTICIDAL ANTHRANILAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070671-A2 | INSECTICIDAL ANTHRANILAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142984-A1 | Insecticidal anthranilamides | ANTXR2, NIT2, AKR7A2 | TSHR 2629/4885CNR2 564/4885CNR1 308/4885 |
| US-20060079561-A1 | Insecticidal anthranilamides | ANTXR2, CYB5R3, NIT2 | TSHR 2153/4885CNR2 589/4885CNR1 357/4885 |
| US-20030229050-A1 | Insecticidal anthranilamides | ANTXR2, NIT2, CYB5R3 | TSHR 2856/4885CNR2 489/4885CNR1 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.