Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.35 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.35 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.35 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.35 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.35 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667320 | 0.89 | OPRK1 (0.50) | OPRM1SLC6A4SLC6A2SLC22A1MEN1 | |
| SCHEMBL5719790 | 0.86 | ATP1A1 (0.33) | OPRM1OPRD1CNR2ATP1A1ATP1B1 | |
| SCHEMBL4663552 | 0.84 | CHRM2 (0.38) | SIGMAR1OPRM1OPRL1OPRD1CHRM2 | |
| SCHEMBL6934477 | 0.82 | SLC6A4 (0.52) | OPRM1OPRL1SLC6A9SLC6A4SLC6A2 | |
| SCHEMBL4664155 | 0.82 | OPRK1 (0.38) | OPRM1OPRL1SLC6A4SLC6A2SLC22A1 | |
| SCHEMBL4663722 | 0.75 | MAOA (0.35) | OPRM1OPRL1OPRK1ATP1A1ATP1B1 | |
| SCHEMBL4664194 | 0.75 | TACR1 (0.34) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL4667252 | 0.74 | OPRM1 (0.37) | SIGMAR1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL4664132 | 0.73 | OPRM1 (0.41) | SIGMAR1OPRM1OPRL1SLC6A9SLC6A4 | |
| SCHEMBL4665510 | 0.72 | SIGMAR1 (0.36) | SIGMAR1OPRM1OPRL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1571140-B1 | C-substituted cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2008-11-12 | — | — | EP | claimed |