Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 3/20 | 0.33 |
| ▸ | ATP1B1 | P05026 | 3/20 | 0.33 |
| ▸ | ATP1A3 | P13637 | 3/20 | 0.33 |
| ▸ | ATP1B2 | P14415 | 3/20 | 0.33 |
| ▸ | ATP1A2 | P50993 | 3/20 | 0.33 |
| ▸ | ATP1B3 | P54709 | 3/20 | 0.33 |
| ▸ | FXYD2 | P54710 | 3/20 | 0.33 |
| ▸ | ATP1A4 | Q13733 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665556 | 0.86 | SIGMAR1 (0.39) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL4664155 | 0.82 | OPRK1 (0.38) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL4667320 | 0.79 | OPRK1 (0.50) | OPRM1OPRD1 | |
| SCHEMBL4663552 | 0.78 | CHRM2 (0.38) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL4664194 | 0.75 | TACR1 (0.34) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL4663722 | 0.75 | MAOA (0.35) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL4667252 | 0.74 | OPRM1 (0.37) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL4665487 | 0.73 | PSEN1 (0.32) | SMN1; SMN2LMNAKDM1ATRPA1OPRM1 | |
| SCHEMBL6937437 | 0.72 | LMNA (0.46) | LMNAGAATRPA1OPRM1OPRD1 | |
| SCHEMBL4665510 | 0.72 | SIGMAR1 (0.36) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368299-B1 | SUBSTITUTED C-CYCLOHEXYLMETHYLAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |