SCHEMBL467416

SCHEMBL467416

CC(=O)c1c(O)cccc1F

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.71
CES2 O00748 2/20 0.54
CES1 P23141 2/20 0.54
CA12 O43570 4/20 0.48
CA1 P00915 4/20 0.48
CA2 P00918 4/20 0.48
CA7 P43166 4/20 0.48
CA9 Q16790 4/20 0.48
CA14 Q9ULX7 4/20 0.48
KMT2A Q03164 3/20 0.46
MAOB P27338 2/20 0.45
SPR P35270 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 2/20 0.42
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
LMNA P02545 1/20 0.41
ALB P02768 1/20 0.41
ERN1 O75460 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL167447 0.86 CES2 (0.64) THRBCES2CES1KMT2ATDP1
SCHEMBL105807 0.84 THRB (1.00) THRBCA12CA1CA2CA7
SCHEMBL31588491 0.80 THRB (0.54) THRBCES2CES1CA12CA1
SCHEMBL617480 0.80 CA12 (0.70) THRBCES2CES1CA12CA1
SCHEMBL27203878 0.79 KMT2A (0.51) THRBCES2CES1CA12CA1
SCHEMBL12160758 0.78 CES2 (0.54) THRBCES2CES1KMT2ATDP1
SCHEMBL8257722 0.78 THRB (0.46) THRBCES2CES1CA12CA1
SCHEMBL8174459 0.78 CES2 (0.54) THRBCES2CES1CA12CA1
SCHEMBL28871108 0.78 CA12 (0.67) THRBCES2CES1CA12CA1
SCHEMBL29691129 0.78 THRB (0.46) THRBCES2CES1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118530786-B Film stripping liquid suitable for flexible circuit board and preparation method thereof 深圳市天熙科技开发有限公司 2024-11-15 CN claimed
CN-118530786-A Film stripping liquid suitable for flexible circuit board and preparation method thereof 深圳市天熙科技开发有限公司 2024-08-23 CN claimed
US-12583856-B2 Inhibitors of protein kinase A BLUEPRINT MEDICINES CORPORATION (US) 2026-03-24 US disclosed
EP-4334298-B1 UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER SCORPION THERAPEUTICS INC (US) 2026-02-18 EP disclosed
US-20250388577-A1 METTL3 INHIBITORY COMPOUNDS STORM THERAPEUTICS LTD (GB) 2025-12-25 US disclosed
US-12492197-B2 3,5-disubstituted pyrazole compounds as kinase inhibitors and uses thereof Impact Therapeutics (Shanghai), Inc (CN) 2025-12-09 US disclosed
US-12473283-B2 Compounds and their use DEBIOPHARM INTERNATIONAL S.A. (CH) 2025-11-18 US disclosed
US-12384801-B2 Benzothiophene, thienopyridine and thienopyrimidine derivatives for the modulation of sting CTXT PTY LTD. (AU) 2025-08-12 US disclosed
US-20250250259-A1 METHODS FOR TREATING CANCER SCORPION THERAPEUTICS, INC. 2025-08-07 US disclosed
US-12358915-B2 METTL3 inhibitory compounds STORM Therapeutics Ltd. (GB) 2025-07-15 US disclosed
US-12312341-B2 Methods for treating cancer SCORPION THERAPEUTICS, INC. (US) 2025-05-27 US disclosed
US-5399584-A Preventing gastrointestinal damage caused by nonsteroidal antiinflammatory drugs THE PROCTER & GAMBLE COMPANY (US) 1995-03-21 US disclosed
WO-1991012255-A1 THERAPEUTIC AGENTS THE BOOTS COMPANY PLC (GB) 1991-08-22 WO disclosed
EP-0224332-B1 HETEROCYCLIC AMINO COMPOUNDS GLAXO GROUP LIMITED (GB) 1990-08-08 EP disclosed
WO-1990001481-A1 THERAPEUTIC AGENTS THE BOOTS COMPANY PLC (GB) 1990-02-22 WO disclosed
EP-0354693-A1 Therapeutic agents The Boots Company PLC (GB) 1990-02-14 EP disclosed
US-4769367-A ANTIDEPRESSANTS GLAXO GROUP LIMITED (GB) 1988-09-06 US disclosed
EP-0224332-A1 Heterocyclic amino compounds GLAXO GROUP LIMITED (GB) 1987-06-03 EP disclosed
EP-0115142-B1 CHROMAN COMPOUNDS ICI AMERICAS INC. (US) 1986-11-05 EP disclosed
EP-0115142-A1 Chroman compounds ICI AMERICAS INC. (US) 1984-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358915-B2 METTL3 inhibitory compounds METTL3, METTL16, DIMT1 THRB 2018/4885CES2 2280/4885CES1 694/4885
US-12384801-B2 Benzothiophene, thienopyridine and thienopyrimidine derivatives for the modulation of sting STING1, CGAS, MAVS THRB 2142/4885CES2 3595/4885CES1 3484/4885
US-12492197-B2 3,5-disubstituted pyrazole compounds as kinase inhibitors and uses thereof CHEK1, CHEK2, CCNK THRB 2718/4885CES2 3253/4885CES1 1409/4885
US-12312341-B2 Methods for treating cancer PIK3CA, PTEN, BRCA1 THRB 1210/4885CES2 1713/4885CES1 1165/4885
US-20250388577-A1 METTL3 INHIBITORY COMPOUNDS METTL3, RNMT, TPMT THRB 329/4885CES2 315/4885CES1 69/4885
US-12583856-B2 Inhibitors of protein kinase A CSNK1A1, CSNK1A1L, CSNK1G1 THRB 493/4885CES2 1936/4885CES1 761/4885
US-20250250259-A1 METHODS FOR TREATING CANCER PIK3CA, PTEN, BRCA1 THRB 1210/4885CES2 1713/4885CES1 1165/4885
US-12473283-B2 Compounds and their use LSS, PGLS, LDHB THRB 2353/4885CES2 793/4885CES1 1604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.