Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 7/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727053 | 0.90 | LMNA (0.52) | SMN1; SMN2MAPTLMNAALPLMEN1 | |
| SCHEMBL4725295 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNATRIM24ALPLALOX12 | |
| SCHEMBL4726021 | 0.89 | LMNA (0.54) | LMNATRIM24ALPL | |
| SCHEMBL4725665 | 0.86 | GHSR (0.44) | MAPTLMNAPKMBRD4MEN1 | |
| SCHEMBL4729316 | 0.84 | CYP19A1 (0.48) | SMN1; SMN2LMNATRIM24ALPLALOX12 | |
| SCHEMBL4728553 | 0.84 | ALPL (0.44) | SMN1; SMN2LMNAALPLPKMMEN1 | |
| SCHEMBL4726489 | 0.81 | LMNA (0.47) | MAPTLMNAPKMMEN1ALDH1A1 | |
| SCHEMBL4727167 | 0.81 | DRD3 (0.45) | MAPTLMNABRD4 | |
| SCHEMBL4726323 | 0.78 | MAPT (0.42) | SMN1; SMN2MAPTLMNAALPLMEN1 | |
| SCHEMBL4725656 | 0.78 | KMT2A (0.45) | SMN1; SMN2MAPTLMNAPKMBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |