SCHEMBL4735417

SCHEMBL4735417

CCCCN(CCCC)c1ccc(C(=O)c2ccccc2C(=O)OC)c(O)c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 2/20 0.76
▸ ALDH1A1 P00352 2/20 0.76
▸ KDM4E B2RXH2 1/20 0.76
▸ POLB P06746 1/20 0.76
▸ L3MBTL1 Q9Y468 3/20 0.57
▸ SMN1; SMN2 Q16637 2/20 0.57
▸ MEN1 O00255 1/20 0.57
▸ KMT2A Q03164 1/20 0.57
▸ TSHR P16473 4/20 0.42
▸ LMNA P02545 3/20 0.42
▸ CYP1A2 P05177 2/20 0.42
▸ CYP2C19 P33261 2/20 0.42
▸ CYP3A4 P08684 2/20 0.42
▸ PGR P06401 1/20 0.42
▸ ADORA3 P0DMS8 1/20 0.42
▸ AR P10275 1/20 0.42
▸ CHRM1 P11229 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ ALOX15 P16050 1/20 0.42
▸ TBXA2R P21731 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL27566360 0.94 ALDH1A1 (0.74) GAAALDH1A1KDM4EPOLBL3MBTL1
SCHEMBL1959291 0.88 SMN1; SMN2 (0.74) GAAALDH1A1KDM4EPOLBL3MBTL1
SCHEMBL267885 0.86 ALDH1A1 (1.00) GAAALDH1A1KDM4EPOLBL3MBTL1
SCHEMBL17212260 0.86 ALDH1A1 (0.81) GAAALDH1A1KDM4EPOLBL3MBTL1
SCHEMBL6745518 0.85 ALDH1A1 (0.69) GAAALDH1A1KDM4EPOLBL3MBTL1
SCHEMBL10933445 0.84 ALDH1A1 (0.95) GAAALDH1A1KDM4EPOLBL3MBTL1
Potassium Ion SCHEMBL28755050 0.84 ALDH1A1 (0.78) GAAALDH1A1KDM4EPOLBL3MBTL1
SCHEMBL27621509 0.84 KDM4E (0.78) GAAALDH1A1KDM4EPOLBL3MBTL1
SCHEMBL3660975 0.83 ALDH1A1 (0.93) GAAALDH1A1KDM4EPOLBL3MBTL1
SCHEMBL264913 0.82 ALDH1A1 (0.91) GAAALDH1A1KDM4EPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1323413-B1 Light screening composition comprising a 1,3,5-triazine derivative, a dibenzoylmethane derivative and an amino substituted 2-hydroxybenzophenone derivative L'ORÉAL (FR) 2016-12-21 — — EP claimed
US-6703002-B2 Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds Societe L′Oreal S.A. (FR) 2004-03-09 — — US claimed
US-6699460-B2 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2004-03-02 — — US claimed
US-6699461-B2 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2004-03-02 — — US claimed
US-6635239-B2 Topically applicable cosmetic/dermatological self-tanning composition with colorations that are more chromatic, are more stable over time, and have good homogeneity SOCIETE L'OREAL S.A. (FR) 2003-10-21 — — US claimed
US-6627180-B2 Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 — — US claimed
US-6627179-B2 Benzotriazole substituted silicon compound or polymer, dibenzoylmethane derivative and an amino-substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 — — US claimed
US-20030180230-A1 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2003-09-25 — — US claimed
US-20030161793-A1 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2003-08-28 — — US claimed
US-20030161794-A1 Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2003-08-28 — — US claimed
US-20030157038-A1 SYNERGISTICALLY UV-PHOTOPROTECTING MIXED SUNSCREEN COMPOSITIONS SOCIETE L'OREAL S.A. (FR) 2003-08-21 — — US claimed
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS SOCIETE L'OREAL S.A. (FR) 2003-08-14 — — US claimed
US-20030129152-A1 STABLE/IMPROVEDLY SELF-TANNING COMPOSITIONS COMPRISING AMINO-SUBSTITUTED 2-HYDROXYBENZOPHENONE COMPOUNDS SOCIETE L'OREAL S.A. (FR) 2003-07-10 — — US claimed
WO-2008060844-A1 POLYMERIZATION INHIBITOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE ALBEMARLE CORPORATION (US) 2008-05-22 — — WO disclosed
US-6703002-B2 Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds Societe L′Oreal S.A. (FR) 2004-03-09 — — US disclosed
US-6699461-B2 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2004-03-02 — — US disclosed
US-20030161794-A1 Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2003-08-28 — — US disclosed
US-20030157038-A1 SYNERGISTICALLY UV-PHOTOPROTECTING MIXED SUNSCREEN COMPOSITIONS SOCIETE L'OREAL S.A. (FR) 2003-08-21 — — US disclosed
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS SOCIETE L'OREAL S.A. (FR) 2003-08-14 — — US disclosed
US-20030129152-A1 STABLE/IMPROVEDLY SELF-TANNING COMPOSITIONS COMPRISING AMINO-SUBSTITUTED 2-HYDROXYBENZOPHENONE COMPOUNDS SOCIETE L'OREAL S.A. (FR) 2003-07-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030180230-A1 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds DHPS, WEE2, DDT GAA 4106/4885ALDH1A1 205/4885KDM4E 1187/4885
US-20030161793-A1 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds HADHB, HADH, NOTUM GAA 3875/4885ALDH1A1 108/4885KDM4E 1621/4885
US-20030161794-A1 Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds HADH, HADHB, BCAS2 GAA 2408/4885ALDH1A1 48/4885KDM4E 2995/4885
US-20030129152-A1 STABLE/IMPROVEDLY SELF-TANNING COMPOSITIONS COMPRISING AMINO-SUBSTITUTED 2-HYDROXYBENZOPHENONE COMPOUNDS TYR, MITF, CYP51A1 GAA 512/4885ALDH1A1 302/4885KDM4E 756/4885
US-20030157038-A1 SYNERGISTICALLY UV-PHOTOPROTECTING MIXED SUNSCREEN COMPOSITIONS PSAT1, TST, BPTF GAA 3251/4885ALDH1A1 693/4885KDM4E 3346/4885
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS HADHB, SDHA, ERCC4 GAA 2810/4885ALDH1A1 193/4885KDM4E 3030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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