Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13983113 | 0.82 | ALOX15 (0.32) | LMNAHPGD | |
| SCHEMBL13983132 | 0.80 | BRD9 (0.33) | LMNAHPGD | |
| SCHEMBL4739107 | 0.79 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL4737070 | 0.79 | ALDH1A1 (0.36) | LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL4734073 | 0.78 | CHIA (0.33) | LMNAKDM4EHPGD | |
| SCHEMBL4737882 | 0.77 | RAB9A (0.35) | LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL4739132 | 0.76 | KDM4E (0.40) | KDM4E | |
| SCHEMBL4737853 | 0.75 | PTGES (0.38) | — | |
| SCHEMBL4739255 | 0.75 | CHRM2 (0.35) | — | |
| SCHEMBL4739290 | 0.75 | PDE10A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151927-A2 | 6-N-SUBSTITUTED BENZ IMIDAZOLE DERIVATIVES AS ACID PUMP ANTAGONISTS | NYCOMED GMBH (DE) | 2008-12-18 | — | — | WO | disclosed |