Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778257 | 1.00 | GLO1 (0.48) | GLO1CYP2D6CYP2C19ALDH1A1TRPA1 | |
| SCHEMBL1618911 | 0.84 | GLO1 (0.50) | GLO1CYP2D6CYP2C19ALDH1A1TRPA1 | |
| SCHEMBL134789 | 0.84 | GLO1 (0.50) | GLO1CYP2D6CYP2C19ALDH1A1TRPA1 | |
| SCHEMBL5293380 | 0.83 | HCAR2 (0.39) | GLO1CYP2D6CYP2C19ALDH1A1TRPA1 | |
| SCHEMBL821828 | 0.82 | GLO1 (0.48) | GLO1CYP2D6CYP2C19ALDH1A1TRPA1 | |
| SCHEMBL3980815 | 0.82 | GLO1 (0.48) | GLO1CYP2D6CYP2C19ALDH1A1TRPA1 | |
| Water SCHEMBL7175634 | 0.82 | GLO1 (0.48) | GLO1CYP2D6CYP2C19ALDH1A1TRPA1 | |
| SCHEMBL1759140 | 0.80 | CYP2D6 (0.51) | GLO1CYP2D6CYP2C19ALDH1A1TRPA1 | |
| SCHEMBL8576396 | 0.80 | GLO1 (0.47) | GLO1CYP2D6CYP2C19ALDH1A1TRPA1 | |
| SCHEMBL8147465 | 0.80 | GLO1 (0.47) | GLO1CYP2D6CYP2C19ALDH1A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113511971-B | 4-halogenated-2-methyl-2-butenoic acid ethyl ester and preparation method thereof | 上虞新和成生物化工有限公司 | 2024-01-30 | — | — | CN | disclosed |
| US-20230134835-A1 | METHODS OF SYNTHESIZING CAROTENOIDS | L E A F HOLDINGS GROUP LLC (US) | 2023-05-04 | — | — | US | disclosed |
| US-20230134835-A1 | METHODS OF SYNTHESIZING CAROTENOIDS | L E A F HOLDINGS GROUP LLC (US) | 2023-05-04 | — | — | US | disclosed |
| CN-113511971-A | 4-halogenated-2-methyl-2-ethyl crotonate and preparation method thereof | 上虞新和成生物化工有限公司 | 2021-10-19 | — | — | CN | disclosed |
| EP-1879902-B1 | COMPOSITION COMPRISING ONE OR MORE LYCOPHYLL DERIVATIVES | CARDAX PHARMA INC (US) | 2020-01-08 | — | — | EP | disclosed |
| EP-1879902-B1 | COMPOSITION COMPRISING ONE OR MORE LYCOPHYLL DERIVATIVES | CARDAX PHARMA INC (US) | 2020-01-08 | — | — | EP | disclosed |
| US-20090099061-A1 | SYNTHESIS OF CAROTENOID ANALOGS OR DERIVATIVES WITH IMPROVED ANTIOXIDANT CHARACTERISTICS | CARDAX PHARMACEUTICALS, INC. | 2009-04-16 | — | — | US | disclosed |
| US-20090099061-A1 | SYNTHESIS OF CAROTENOID ANALOGS OR DERIVATIVES WITH IMPROVED ANTIOXIDANT CHARACTERISTICS | CARDAX PHARMACEUTICALS, INC. | 2009-04-16 | — | — | US | disclosed |
| US-7435861-B2 | carotenes or xanthophylls, used as free radical scavengers; cytoprotective agents; oxidation resistance | CARDAX PHARMACEUTICALS, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-7435861-B2 | carotenes or xanthophylls, used as free radical scavengers; cytoprotective agents; oxidation resistance | CARDAX PHARMACEUTICALS, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-20060293545-A1 | carotenes or xanthophylls, used as free radical scavengers; cytoprotective agents; oxidation resistance | CARDAX PHARMA, INC. | 2006-12-28 | — | — | US | disclosed |
| WO-2006119125-A2 | METHODS FOR SYNTHESIS OF CAROTENOIDS, INCLUDING ANALOGS, DERIVATIVES, AND SYNTHETIC AND BIOLOGICAL INTERMEDIATES | CARDAX PHARMACEUTICALS, INC. (US) | 2006-11-09 | — | — | WO | disclosed |
| US-20060183947-A1 | Stereoselectively reducing 2,6,6-trimethyl-2-cyclohexene-1,4-dione with an optically active chiral catalyst to form an optically active hydroxycyclohexenone, contacting the product with a reducing agent to form an optically active diol, and using the diol to form astaxanthin | CARDAX PHARMA, INC. | 2006-08-17 | — | — | US | disclosed |
| US-20060183185-A1 | Method for the synthesis of astaxanthin | CARDAX PHARMACEUTICALS, INC. | 2006-08-17 | — | — | US | disclosed |
| US-20060178538-A1 | Methods for the synthesis of chiral dihydroxy intermediates useful for the chiral synthesis of carotenoids | CARDAX PHARMACEUTICALS, INC. | 2006-08-10 | — | — | US | disclosed |
| US-20060155150-A1 | Methods for the synthesis of lutein | CARDAX PHARMACEUTICALS, INC. | 2006-07-13 | — | — | US | disclosed |
| US-20060111580-A1 | Methods for the synthesis of chiral dihydroxy ketone intermediates useful for the chiral synthesis of carotenoids | CARDAX PHARMACEUTICALS, INC. | 2006-05-25 | — | — | US | disclosed |
| US-20060088904-A1 | Methods for the synthesis of astaxanthin | CARDAX PHARMACEUTICALS, INC. | 2006-04-27 | — | — | US | disclosed |
| WO-2006039685-A2 | METHODS FOR SYNTHESIS OF CHIRAL INTERMEDIATES OF CAROTENOIDS, CAROTENOID ANALOGS, AND CAROTENOID DERIVATIVES | HAWAII BIOTECH, INC. (US) | 2006-04-13 | — | — | WO | disclosed |
| US-5717128-A | HEATING AN ESTER OF 2-HYDROXY-2-METHYL-3-BUTENOIC ACID WITH PHOSPHOROUS BROMIDE OR CHLORIDE; THEN WITH TRIALKYL ESTER OF PHOSPHOROUS ACID | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060088904-A1 | Methods for the synthesis of astaxanthin | HSD17B7, CYP51A1, HSD11B1 | GLO1 325/4885CYP2D6 321/4885CYP2C19 855/4885 |
| US-20060293545-A1 | carotenes or xanthophylls, used as free radical scavengers; cytoprotective agents; oxidation resistance | TXNRD2, TXN2, TXNRD1 | GLO1 412/4885CYP2D6 2359/4885CYP2C19 2413/4885 |
| US-20060178538-A1 | Methods for the synthesis of chiral dihydroxy intermediates useful for the chiral synthesis of carotenoids | HSD17B7, DHPS, DHCR7 | GLO1 264/4885CYP2D6 254/4885CYP2C19 429/4885 |
| US-20060155150-A1 | Methods for the synthesis of lutein | LSS, DHPS, CYP51A1 | GLO1 96/4885CYP2D6 539/4885CYP2C19 896/4885 |
| US-20060183947-A1 | Stereoselectively reducing 2,6,6-trimethyl-2-cyclohexene-1,4-dione with an optically active chiral catalyst to form an optically active hydroxycyclohexenone, contacting the product with a reducing agent to form an optically active diol, and using the diol to form astaxanthin | DHCR7, HSD17B7, HSD11B1 | GLO1 524/4885CYP2D6 117/4885CYP2C19 923/4885 |
| US-20090099061-A1 | SYNTHESIS OF CAROTENOID ANALOGS OR DERIVATIVES WITH IMPROVED ANTIOXIDANT CHARACTERISTICS | CAT, HBZ, POLL | GLO1 446/4885CYP2D6 376/4885CYP2C19 708/4885 |
| US-20060111580-A1 | Methods for the synthesis of chiral dihydroxy ketone intermediates useful for the chiral synthesis of carotenoids | DHPS, DHCR7, HSD17B7 | GLO1 249/4885CYP2D6 370/4885CYP2C19 869/4885 |
| US-20060183185-A1 | Method for the synthesis of astaxanthin | SQLE, HSD17B7, CYP51A1 | GLO1 543/4885CYP2D6 504/4885CYP2C19 1025/4885 |
| US-20230134835-A1 | METHODS OF SYNTHESIZING CAROTENOIDS | HCCS, GYS2, GYS1 | GLO1 3432/4885CYP2D6 2585/4885CYP2C19 3443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.