Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729316 | 0.93 | CYP19A1 (0.48) | SMN1; SMN2LMNAMEN1ALOX12KMT2A | |
| SCHEMBL4727053 | 0.91 | LMNA (0.52) | SMN1; SMN2LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL4779869 | 0.90 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAMEN1ALOX12KMT2A | |
| SCHEMBL4726021 | 0.90 | LMNA (0.54) | LMNAL3MBTL1NPSR1HTTTP53 | |
| SCHEMBL4728553 | 0.85 | ALPL (0.44) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL4726489 | 0.82 | LMNA (0.47) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL4726323 | 0.79 | MAPT (0.42) | SMN1; SMN2LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL4725656 | 0.79 | KMT2A (0.45) | SMN1; SMN2LMNAMEN1ALOX12KMT2A | |
| SCHEMBL4727679 | 0.79 | ALDH1A1 (0.48) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL4727604 | 0.78 | MEN1 (0.47) | LMNAMEN1KMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |