Thymine

Thymine

SCHEMBL48230

Cc1c[nH]c(=O)[nH]c1=O.OCCO

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ATAD2 Q6PL18 1/20 0.79
▸ GAA P10253 2/20 0.50
▸ MAPT P10636 2/20 0.50
▸ DPYD Q12882 4/20 0.43
▸ LMNA P02545 3/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ CYP19A1 P11511 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ THPO P40225 1/20 0.43
▸ MTOR P42345 1/20 0.43
▸ HTT P42858 1/20 0.43
▸ HBB P68871 1/20 0.43
▸ PMP22 Q01453 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thymine SCHEMBL23794979 0.89 ATAD2 (0.91) ATAD2GAAMAPTDPYDLMNA
Thymine SCHEMBL750450 0.89 ATAD2 (1.00) ATAD2GAAMAPTDPYDLMNA
Thymine SCHEMBL5235 0.89 — —
Thymine SCHEMBL17201833 0.89 ATAD2 (1.00) ATAD2GAAMAPTDPYDLMNA
Thymine SCHEMBL29669526 0.89 — —
Thymine SCHEMBL15323914 0.89 ATAD2 (1.00) ATAD2GAAMAPTDPYDLMNA
Thymine SCHEMBL3025204 0.87 ATAD2 (0.86) ATAD2GAAMAPTDPYDLMNA
Thymine SCHEMBL8304490 0.87 ATAD2 (0.86) ATAD2GAAMAPTDPYDLMNA
Thymine SCHEMBL8649294 0.87 ATAD2 (0.95) ATAD2GAAMAPTDPYDLMNA
Thymine SCHEMBL5176783 0.87 ATAD2 (0.95) ATAD2GAAMAPTDPYDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630851-B2 Polynucleotide modification methods OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-19 — — US claimed
US-20260098287-A1 METHOD AND KIT FOR REGENERATING REUSABLE INITIATORS FOR NUCLEIC ACID SYNTHESIS CHENG-YAO CHEN (TW) 2026-04-09 — — US claimed
US-12577615-B2 Methods for the detection of a nucleic acid RHODX, INC. (US) 2026-03-17 — — US claimed
WO-2025245282-A1 COMPOSITIONS AND METHODS FOR DETECTION OF PROTEIN ANALYTES RANGE BIOTECHNOLOGIES, INC. (US) 2025-11-27 — — WO claimed
US-20250340935-A1 METHODS FOR THE DETECTION OF A NUCLEIC ACID RHODX INC (US) 2025-11-06 — — US claimed
EP-4569132-A2 METHOD, KIT AND SYSTEM FOR END LABELING OF NUCLEIC ACIDS Chen, Cheng-Yao (TW) 2025-06-18 — — EP claimed
WO-2025021984-A1 METHOD FOR GENERATING A PLURALITY OF POLYNUCLEOTIDES DNA SCRIPT (FR) 2025-01-30 — — WO claimed
US-20250019744-A1 METHOD, KIT AND SYSTEM FOR END LABELING OF NUCLEIC ACIDS Chen, Cheng-Yao (TW) 2025-01-16 — — US claimed
US-12084715-B1 Methods and systems for reducing artifactual antisense products 10X GENOMICS, INC. (US) 2024-09-10 — — US claimed
US-20240175010-A1 Methods of Library Preparation ILLUMINA, INC. (US) 2024-05-30 — — US claimed
WO-2002076280-A2 METHODS AND KITS FOR DETERMING A RISK TO DEVELOP CANCER, FOR EVALUATING AN EFFECTIVENESS AND DOSAGE OF CANCER THERAPY AND FOR CORRELATING BETWEEN AN ACTIVITY OF A DNA REPAIR ENZYME AND A CANCER YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2002-10-03 — — WO claimed
US-20020055104-A1 Nucleic acid binding site assay and selection method GENELABS TECHNOLOGIES, INC. 2002-05-09 — — US claimed
WO-2001051669-A9 NUCLEIC ACID BINDING ASSAY AND SELECTION METHOD GENELABS TECH INC (US) 2001-11-29 — — WO claimed
WO-2001051669-A2 NUCLEIC ACID BINDING ASSAY AND SELECTION METHOD GENELABS TECHNOLOGIES, INC. (US) 2001-07-19 — — WO claimed
US-5906918-A QUANTITATING BASE MODIFICATIONS IN SAMPLE DNA BY ENDONUCLEASE DIGESTION TO DINUCLEOSIDE MONOPHOSPHATES, DEPHOSPHORYLATION, LABELING SAMPLE AND INTERNAL STANDARD DNA, ADDING COMIGRATING CARRIERS, SEPARATING SAMPLE/CARRIER FROM STANDARD/CARRIER HEALTH RESEARCH INC. (US) 1999-05-25 — — US claimed
US-5871992-A REPAIR OF DNA WITH ENZYME OF GLYCOSYLASE/AP LYASE ALSO FUSION PROTEINS NEW YORK UNIVERSITY (US) 1999-02-16 — — US claimed
US-5763180-A In vitro assay for carcinogens using phenotypic transformation of human cells VIRATEST CARCINOGEN MONITORING LTD. (CA) 1998-06-09 — — US claimed
WO-1997031612-A2 MAMMALIAN ENDONUCLEASE III, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF NEW YORK UNIVERSITY (US) 1997-09-04 — — WO claimed
US-5552285-A DIAGNOSIS AND MONITORING OF INFLAMMATORY AND AUTOIMMUNE DISEASES NEW YORK UNIVERSITY (US) 1996-09-03 — — US claimed
WO-1992015707-A1 IMMUNOASSAY FOR ANTIBODIES TO OXIDIZED DNA AND USES THEREOF NEW YORK UNIVERSITY (US) 1992-09-17 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577615-B2 Methods for the detection of a nucleic acid POLRMT, RNGTT, RNASE1 ATAD2 4183/4885GAA 663/4885MAPT 4803/4885
US-12630851-B2 Polynucleotide modification methods PNP, NT5C3B, UNG ATAD2 2669/4885GAA 1181/4885MAPT 3328/4885
US-20260098287-A1 METHOD AND KIT FOR REGENERATING REUSABLE INITIATORS FOR NUCLEIC ACID SYNTHESIS DNMT3L, ADAR, UNG ATAD2 352/4885GAA 391/4885MAPT 4124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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