SCHEMBL4859988

SCHEMBL4859988

CC(C)(Br)C(=O)C(C)(C)Br

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14976728 0.85 L3MBTL1 (0.38) ALDH1A1TSHR
SCHEMBL8010270 0.82
SCHEMBL29246489 0.79 THRB (0.30) ALDH1A1TSHR
SCHEMBL1370508 0.75
SCHEMBL5006941 0.75 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL2302184 0.75
SCHEMBL138469 0.75
SCHEMBL108911 0.75
SCHEMBL10453712 0.75
Bromide SCHEMBL258976 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11772085-B2 Far superior oxidation catalysts based on macrocyclic compounds CARNEGIE MELLON UNIVERSITY (US) 2023-10-03 US disclosed
WO-2022147214-A2 CYCLIC-DISULFIDE MODIFIED PHOSPHATE BASED OLIGONUCLEOTIDE PRODRUGS ALNYLAM PHARMACEUTICALS, INC. (US) 2022-07-07 WO disclosed
EP-4015511-A1 OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS CARNEGIE MELLON UNIVERSITY (US) 2022-06-22 EP disclosed
EP-3245557-B1 ELECTROCHROMIC MULTI-LAYER DEVICES WITH CHARGE SEQUESTRATION AND RELATED METHODS KINESTRAL TECH INC (US) 2021-12-15 EP disclosed
EP-3353157-B1 OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS UNIV CARNEGIE MELLON (US) 2021-11-24 EP disclosed
US-20210086171-A1 FAR SUPERIOR OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS CARNEGIE MELLON UNIVERSITY 2021-03-25 US disclosed
US-10926248-B2 Far superior oxidation catalysts based on macrocyclic compounds CARNEGIE MELLON UNIVERSITY (US) 2021-02-23 US disclosed
CN-107873090-B Electrochromic multilayer devices using charge trapping and related methods 基内斯托技术公司 2020-07-31 CN disclosed
US-10698286-B2 Electrochromic multi-layer devices with charge sequestration and related methods KINESTRAL TECHNOLOGIES, INC. (US) 2020-06-30 US disclosed
US-20200048347-A1 BISPECIFIC ANTIBODIES IMMUNOMAB, INC. 2020-02-13 US disclosed
EP-0034876-B1 BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF PFIZER INC. (US) 1984-08-29 EP disclosed
US-4454328-A SWEETENERS PFIZER INC. (US) 1984-06-12 US disclosed
EP-0028430-B1 A PROCESS FOR THE ELECTROREDUCTIVE PREPARATION OF ORGANIC COMPOUNDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1984-01-18 EP disclosed
US-4411925-A STABLE SWEETENERS PFIZER INC. (US) 1983-10-25 US disclosed
US-4399163-A ARTIFICIAL SWEETENERS PFIZER INC. (US) 1983-08-16 US disclosed
EP-0069811-A1 Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof PFIZER INC. (US) 1983-01-19 EP disclosed
EP-0034876-A2 Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof PFIZER INC. (US) 1981-09-02 EP disclosed
EP-0028430-A1 A process for the electroreductive preparation of organic compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1981-05-13 EP disclosed
US-4086251-A POLYPROPYLENE, POLYBUTYLENE WITH AN ANHYDRIDE STANDARD OIL COMPANY (INDIANA) (US) 1978-04-25 US disclosed
US-3953475-A MALEIC ANHYDRIDE STANDARD OIL COMPANY (US) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048347-A1 BISPECIFIC ANTIBODIES FCGR3B, CD2BP2, CD22 ALDH1A1 4136/4885TSHR 2489/4885
US-10926248-B2 Far superior oxidation catalysts based on macrocyclic compounds ME3, SOD1, DUOX1 ALDH1A1 1400/4885TSHR 1297/4885
US-11772085-B2 Far superior oxidation catalysts based on macrocyclic compounds SOD1, ME3, ME2 ALDH1A1 1499/4885TSHR 1480/4885
US-20210086171-A1 FAR SUPERIOR OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS ME3, ME2, ME1 ALDH1A1 1801/4885TSHR 1881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.