Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14539438 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL918774 | 0.82 | HDAC3 (0.49) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14394145 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11100301 | 0.76 | ALKBH5 (0.58) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1581464 | 0.75 | ALDH1A1 (0.68) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28196055 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6320924 | 0.74 | ALDH1A1 (0.61) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL879474 | 0.74 | ALDH1A1 (0.61) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL133738 | 0.73 | ALDH1A1 (0.87) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5031039 | 0.73 | ALDH1A1 (0.65) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7385087-B2 | Method for producing a-(3-arylthio)-acetophenones | BASF AKTIENGESELLSCHAFT (DE) | 2008-06-10 | — | — | US | claimed |
| EP-1678127-B1 | METHOD FOR THE PRODUCTION OF ALPHA-(3-ARYLTHIO)-ACETOPHENONES | BASF AG (DE) | 2007-07-25 | — | — | EP | claimed |
| US-20070060776-A1 | Method for the production of alpha-(3-arylthio)-acetophenones | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | claimed |
| EP-1603868-B1 | METHOD FOR PRODUCING ALPHA-(3-ARYLTHIO)-ACETOPHENONES | BASF AG (DE) | 2006-09-13 | — | — | EP | claimed |
| US-20060178537-A1 | Method for producing a-(3-arylthio)-acetophenones | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-10 | — | — | US | claimed |
| EP-1678127-A1 | METHOD FOR THE PRODUCTION OF ALPHA-(3-ARYLTHIO)-ACETOPHENONES | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-12 | — | — | EP | claimed |
| EP-1603868-A1 | METHOD FOR PRODUCING a-(3-ARYLTHIO)-ACETOPHENONES | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-14 | — | — | EP | claimed |
| WO-2005042477-A1 | METHOD FOR THE PRODUCTION OF $G(A)-(3-ARYLTHIO)-ACETOPHENONES | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-12 | — | — | WO | claimed |
| WO-2004078705-A1 | METHOD FOR PRODUCING α-(3-ARYLTHIO)-ACETOPHENONES | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-16 | — | — | WO | claimed |
| US-7385087-B2 | Method for producing a-(3-arylthio)-acetophenones | BASF AKTIENGESELLSCHAFT (DE) | 2008-06-10 | — | — | US | disclosed |
| US-7385087-B2 | Method for producing a-(3-arylthio)-acetophenones | BASF AKTIENGESELLSCHAFT (DE) | 2008-06-10 | — | — | US | disclosed |
| US-7385087-B2 | Method for producing a-(3-arylthio)-acetophenones | BASF AKTIENGESELLSCHAFT (DE) | 2008-06-10 | — | — | US | disclosed |
| CN-100345824-C | Preparation method of alpha- (3-arylthio) acetophenone | BASF AG (DE) | 2007-10-31 | — | — | CN | disclosed |
| CN-100345824-C | Preparation method of alpha- (3-arylthio) acetophenone | BASF AG (DE) | 2007-10-31 | — | — | CN | disclosed |
| EP-1603868-A1 | METHOD FOR PRODUCING a-(3-ARYLTHIO)-ACETOPHENONES | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-14 | — | — | EP | disclosed |
| EP-1603868-A1 | METHOD FOR PRODUCING a-(3-ARYLTHIO)-ACETOPHENONES | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-14 | — | — | EP | disclosed |
| WO-2005042477-A1 | METHOD FOR THE PRODUCTION OF $G(A)-(3-ARYLTHIO)-ACETOPHENONES | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-12 | — | — | WO | disclosed |
| WO-2005042477-A1 | METHOD FOR THE PRODUCTION OF $G(A)-(3-ARYLTHIO)-ACETOPHENONES | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-12 | — | — | WO | disclosed |
| WO-2004078705-A1 | METHOD FOR PRODUCING α-(3-ARYLTHIO)-ACETOPHENONES | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-16 | — | — | WO | disclosed |
| WO-2004078705-A1 | METHOD FOR PRODUCING α-(3-ARYLTHIO)-ACETOPHENONES | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060776-A1 | Method for the production of alpha-(3-arylthio)-acetophenones | CBR3, CYB5R3, ME3 | ALDH1A1 764/4885HDAC3 86/4885HDAC4 1258/4885 |
| US-20060178537-A1 | Method for producing a-(3-arylthio)-acetophenones | ARSA, TST, SULT1A1 | ALDH1A1 74/4885HDAC3 1439/4885HDAC4 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.