SCHEMBL489573

SCHEMBL489573

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nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9504057 1.00 PAX8 (0.44) PAX8
SCHEMBL3899055 1.00 PAX8 (0.44) PAX8
SCHEMBL3158180 1.00 PAX8 (0.44) PAX8
SCHEMBL9504052 1.00 PAX8 (0.44) PAX8
SCHEMBL29425221 1.00 PAX8 (0.44) PAX8
SCHEMBL476387 1.00 PAX8 (0.44) PAX8
SCHEMBL4459290 1.00 PAX8 (0.44) PAX8
Hydrochloric Acid SCHEMBL1722152 0.97 PAX8 (0.43) PAX8
SCHEMBL14151119 0.97 PAX8 (0.43) PAX8
SCHEMBL11403360 0.97 PAX8 (0.43) PAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 452 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107335-A1 COMPOSITIONS AND METHODS FOR TREATING HEPATIC DISEASES BY INHIBITING EFHD1 UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2026-05-21 WO claimed
US-20260092179-A1 GENETICALLY MODIFIED HOST CELLS PRODUCING VIOLACEIN, ANALOGUES, AND DERIVATIVES THEREOF OCTARINE BIO APS (DK) 2026-04-02 US claimed
US-20250333730-A1 SIRNA FOR INHIBITING ANGPTL3 GENE EXPRESSION AND USE THEREOF SHANGHAI JUNSHI BIOSCIENCES CO LTD (CN) 2025-10-30 US claimed
US-20250213698-A1 BICYCLIC HETEROCYCLES AND THEIR LIGANDS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) 2025-07-03 US claimed
US-12290567-B2 Asialoglycoprotein Receptor mediated delivery of therapeutically active conjugates ARCTURUS THERAPEUTICS, INC. (US) 2025-05-06 US claimed
WO-2025083657-A1 LIPID COMPOUND AND COMPOSITION FOR TISSUE-SPECIFIC DELIVERY OF ACTIVE SUBSTANCE 한국생명공학연구원 2025-04-24 WO claimed
EP-4499830-A1 BICYCLIC HETEROCYCLES AND THEIR LIGANDS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS Hansoh Bio LLC (US) 2025-02-05 EP claimed
US-20250034080-A1 CATIONIC LIPID CONTAINING SIDE-CHAIN FUNCTIONAL GROUPS AND APPLICATION THEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2025-01-30 US claimed
US-20240392289-A1 LIGAND CONJUGATES FOR DELIVERY OF THERAPEUTICALLY ACTIVE AGENTS Hepagene Therapeutics (HK) Limited (CN) 2024-11-28 US claimed
EP-4458805-A1 CATIONIC LIPID CONTAINING FUNCTIONAL GROUP ON SIDE CHAIN, AND USE THEREOF Xiamen Sinopeg Biotech Co., Ltd. (CN) 2024-11-06 EP claimed
US-20170028074-A1 MultiLigand Agent for Drug Delivery ARCTURUS THERAPEUTICS, INC. 2017-02-02 US claimed
EP-2456772-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR PROTECTING BRAIN HEALTH IN NEURODEGENERATIVE DISORDERS Amazentis SA (CH) 2012-05-30 EP claimed
WO-2011011721-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR PROTECTING BRAIN HEALTH IN NEURODEGENERATIVE DISORDERS AMAZENTIS SA (CH) 2011-01-27 WO claimed
US-20090325891-A1 Cartilage regeneration-promoting agent EISAI FOOD & CHEMICAL CO., LTD. 2009-12-31 US claimed
WO-2007099392-A2 CONVERGENT SYNTHESIS OF CARBOHYDRATE BUILDING BLOCKS SWISS FEDERAL INSTITUTE OF TECHNOLOGY (US) 2007-09-07 WO claimed
EP-0320960-B1 AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1993-05-12 EP claimed
US-5145848-A AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1992-09-08 US claimed
EP-0396588-A1 AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1990-11-14 EP claimed
WO-1989005815-A1 AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1989-06-29 WO claimed
EP-0320960-A1 Amino anthracenediones-bis platinum complexes, useful as antitumoral agents BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1989-06-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092179-A1 GENETICALLY MODIFIED HOST CELLS PRODUCING VIOLACEIN, ANALOGUES, AND DERIVATIVES THEREOF TDO2, BLVRB, INMT PAX8 4054/4885
US-12290567-B2 Asialoglycoprotein Receptor mediated delivery of therapeutically active conjugates ASGR1, FCGR2A, FCGR3B PAX8 4083/4885
US-20240392289-A1 LIGAND CONJUGATES FOR DELIVERY OF THERAPEUTICALLY ACTIVE AGENTS FCGR2A, ASGR1, APLNR PAX8 3532/4885
US-20250333730-A1 SIRNA FOR INHIBITING ANGPTL3 GENE EXPRESSION AND USE THEREOF TEK, TIE1, PCSK9 PAX8 3007/4885
US-20170028074-A1 MultiLigand Agent for Drug Delivery NPC1L1, LDLR, CETP PAX8 4133/4885
US-20250213698-A1 BICYCLIC HETEROCYCLES AND THEIR LIGANDS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS PAICS, ABCG2, FOLR1 PAX8 4511/4885
US-20090325891-A1 Cartilage regeneration-promoting agent HGF, COL2A1, HDGF PAX8 163/4885
US-20250034080-A1 CATIONIC LIPID CONTAINING SIDE-CHAIN FUNCTIONAL GROUPS AND APPLICATION THEREOF PHOSPHO1, LIPA, SLC7A1 PAX8 4861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.