Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA6 | P23280 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.58 |
| ▸ | IGF1R | P08069 | 3/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.58 |
| ▸ | XDH | P47989 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276668 | 0.80 | ALOX15 (0.67) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL27740708 | 0.78 | ALOX15 (0.50) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL27719648 | 0.78 | CA2 (0.57) | CA1CA2ALOX15IGF1RHSD17B10 | |
| SCHEMBL27829497 | 0.78 | ESR1 (0.68) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL6104943 | 0.78 | THRB (0.40) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL107956 | 0.78 | ALOX15 (0.80) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL30631592 | 0.78 | ALOX15 (0.80) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL108093 | 0.78 | CA1 (1.00) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL7845022 | 0.77 | ALOX15 (0.75) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL109054 | 0.76 | CA1 (0.94) | CA1CA2CA4CA6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240180932-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS | NESTLE SA (CH) | 2024-06-06 | — | — | US | claimed |
| CN-117705184-A | Detection method for chemical components of anemone-resistant tung tree | 中国热带农业科学院热带作物品种资源研究所 | 2024-03-15 | — | — | CN | claimed |
| EP-4313017-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS | Société des Produits Nestlé S.A. (CH) | 2024-02-07 | — | — | EP | claimed |
| US-20230414638-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS AS AMPK ACTIVATOR AND USES THEREOF | NESTLE SA (CH) | 2023-12-28 | — | — | US | claimed |
| WO-2023213715-A1 | AMPK ACTIVATOR (CBDA) AND SGLT2 INHIBITOR FOR METABOLIC HEALTH | Société des Produits Nestlé S.A. (CH) | 2023-11-09 | — | — | WO | claimed |
| CN-116981452-A | Substituted resorcinol compounds for the management of aging and related disorders | 雀巢产品有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-109843849-B | Amide compounds, pharmaceutical compositions thereof, and methods of use thereof | 俄勒冈健康科学大学 | 2023-09-22 | — | — | CN | claimed |
| CN-116761791-A | Substituted resorcinol compounds as AMPK activators and uses thereof | 雀巢产品有限公司 | 2023-09-15 | — | — | CN | claimed |
| EP-4240342-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS AS AMPK ACTIVATOR AND USES THEREOF | Société des Produits Nestlé S.A. (CH) | 2023-09-13 | — | — | EP | claimed |
| WO-2022096423-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS AS AMPK ACTIVATOR AND USES THEREOF | Société des Produits Nestlé S.A. (CH) | 2022-05-12 | — | — | WO | claimed |
| WO-1998019693-A1 | COMBINATORIAL LIBRARIES OF CYCLIC UREA AND CYCLIC THIOUREA DERIVATIVES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-05-14 | — | — | WO | claimed |
| WO-1996014064-A1 | METHOD AND COMPOSITION FOR ANTIVIRAL THERAPY | STRECKER, ROBERT, B. (US) | 1996-05-17 | — | — | WO | claimed |
| EP-0429245-B1 | A therapeutic agent for central nervous diseases | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-02-07 | — | — | EP | claimed |
| EP-0412820-B1 | 2-Oxo-1-oxa-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1994-03-02 | — | — | EP | claimed |
| EP-0256726-B1 | ENCAPSULATION OF TRH OR ITS ANALOG | Takeda Chemical Industries, Ltd. (JP) | 1992-10-07 | — | — | EP | claimed |
| EP-0429245-A2 | A therapeutic agent for central nervous diseases | Takeda Chemical Industries, Ltd. (JP) | 1991-05-29 | — | — | EP | claimed |
| CN-1043717-A | Cephalosporin compound | TANABE SEIYAKU CO (JP) | 1990-07-11 | — | — | CN | claimed |
| EP-0376724-A2 | Cephalosporin compounds | TANABE SEIYAKU CO., LTD. (JP) | 1990-07-04 | — | — | EP | claimed |
| EP-0256726-A2 | Encapsulation of TRH or its analog | Takeda Chemical Industries, Ltd. (JP) | 1988-02-24 | — | — | EP | claimed |
| US-3979390-A | Butyrophenone derivatives and production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-09-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230414638-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS AS AMPK ACTIVATOR AND USES THEREOF | PRKAG2, PRKAB2, PRKAG1 | CA1 4233/4885CA2 1776/4885CA4 3162/4885 |
| US-20240180932-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS | HSPA9, CS, SQSTM1 | CA1 4478/4885CA2 2236/4885CA4 2786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.