Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 14/20 | 0.49 |
| ▸ | GCG | P01275 | 2/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492888 | 0.88 | SHMT1 (0.48) | MMEGSK3BHDAC4HDAC6ALDH1A1 | |
| SCHEMBL493476 | 0.81 | FABP4 (0.48) | GCGRGSK3B | |
| SCHEMBL494459 | 0.80 | HDAC4 (0.50) | HDAC4HDAC6 | |
| SCHEMBL28816298 | 0.76 | ALPL (0.50) | HDAC4HDAC6ALDH1A1 | |
| SCHEMBL493213 | 0.74 | KMT2A (0.41) | MMEALDH1A1 | |
| SCHEMBL28816278 | 0.72 | HTT (0.56) | HDAC4HDAC6ALDH1A1 | |
| SCHEMBL493923 | 0.72 | KMT2A (0.65) | — | |
| SCHEMBL28044246 | 0.72 | CTSA (0.61) | GCGR | |
| SCHEMBL493260 | 0.71 | SMN1; SMN2 (0.75) | — | |
| SCHEMBL493896 | 0.71 | FAAH (0.56) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | GCGR 2660/4885GCG 769/4885MME 1616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.