Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Naphthalene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.39 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.39 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.32 |
| ▸ | LIG1 | P18858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL1563628 | 0.86 | CA2 (0.36) | CA12CA2CA9CA1CA7 | |
| Phenol SCHEMBL28240227 | 0.84 | ESR1 (0.43) | CA12CA2CA9CA1CA7 | |
| SCHEMBL131938 | 0.84 | RECQL (0.37) | CA12CA2CA9CA1CA7 | |
| SCHEMBL62283 | 0.84 | — | — | |
| Benzene SCHEMBL9502651 | 0.82 | CA2 (0.36) | CA12CA2CA9CA1CA7 | |
| Methane SCHEMBL28948869 | 0.82 | RECQL (0.35) | CA12CA2CA9CA1CA7 | |
| Sulfuric Acid SCHEMBL8733611 | 0.82 | RECQL (0.35) | CA12CA2CA9CA1CA7 | |
| Water SCHEMBL10588110 | 0.82 | RECQL (0.35) | CA12CA2CA9CA1CA7 | |
| Phenol SCHEMBL7587323 | 0.81 | ESR1 (0.43) | CA12CA2CA9CA1CA7 | |
| SCHEMBL9056640 | 0.80 | CA2 (0.35) | CA12CA2CA9CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115530160-B | Propanil dry suspending agent and preparation method thereof | 祥霖美丰生物科技(淮安)有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-110338193-A | Penoxsulam preparation and preparation method thereof | 湖北广富林生物制剂有限公司 | 2019-10-18 | — | — | CN | claimed |
| CN-109526975-A | Five fluorine Herbicidal combinations of a kind of third pyrrole and preparation method thereof | 山东耘歌生物科技有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-108849877-A | It is a kind of to contain pyrazosulfuron, mefenacet and effervescent formulation of Huan Wu Evil humulone and preparation method thereof | 山东耘歌生物科技有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108849889-A | A kind of effervescent formulation and its preparation process containing furans sulphur humulone and mefenacet | 山东耘歌生物科技有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108812653-A | It is a kind of to contain pyrazosulfuron, pretilachlor and effervescent formulation of furans sulphur humulone and preparation method thereof | 山东耘歌生物科技有限公司 | 2018-11-16 | — | — | CN | claimed |
| CN-108617678-A | A kind of effervescent formulation and preparation method thereof containing pyrazosulfuron, pretilachlor and three azole amides | 山东耘歌生物科技有限公司 | 2018-10-09 | — | — | CN | claimed |
| CN-108605966-A | A kind of effervescent formulation and its preparation process containing furans sulphur humulone, mefenacet and piperazine pyrazosulfuron | 山东耘歌生物科技有限公司 | 2018-10-02 | — | — | CN | claimed |
| CN-108552199-A | A kind of effervescent formulation and its preparation process containing pyrazosulfuron, pretilachlor and pentoxazone | 山东耘歌生物科技有限公司 | 2018-09-21 | — | — | CN | claimed |
| CN-108496970-A | A kind of composition, preparation and its application for desinsection | 四川国光农化股份有限公司 | 2018-09-07 | — | — | CN | claimed |
| CN-108402066-A | A kind of effervescent formulation and its preparation process containing furans sulphur humulone, pyraclonil and piperazine pyrazosulfuron | 山东耘歌生物科技有限公司 | 2018-08-17 | — | — | CN | claimed |
| US-7470419-B2 | Granules of powdery mineral and method for production of granules | ELKEM AS (NO) | 2008-12-30 | — | — | US | claimed |
| CN-116686831-B | Water dispersible tablet containing pretilachlor, pyrazosulfuron-ethyl and penoxsulam as well as preparation method and application thereof | 山东科赛基农生物工程有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116686831-A | Water dispersible tablet containing pretilachlor, pyrazosulfuron-ethyl and penoxsulam as well as preparation method and application thereof | 山东科赛基农生物工程有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-115530160-B | Propanil dry suspending agent and preparation method thereof | 祥霖美丰生物科技(淮安)有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-116082560-A | Environment-friendly efficient formaldehyde-removing styrene-acrylic emulsion for interior wall and preparation method thereof | 广东银洋环保新材料有限公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-0111338-B1 | COATING PROCESS EMPLOYS SURFACTANTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-25 | — | — | EP | disclosed |
| EP-0111338-A2 | Coating process employs surfactants | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-20 | — | — | EP | disclosed |
| US-4185113-A | MANGANESE OR ZINC SALT WITH CINNAMIC ALDEHYDE AS FUNGICIDE | ROUSSEL UCLAF (FR) | 1980-01-22 | — | — | US | disclosed |
| US-4162920-A | OLEOPHILIC SURFACTANT AND TAPIOCA DEXTRIN | AMERICAN HOECHST CORPORATION (US) | 1979-07-31 | — | — | US | disclosed |