SCHEMBL4968638

SCHEMBL4968638

COc1ccc(/C=C(/C#N)C(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
KDM4E B2RXH2 2/20 0.65
CYP3A4 P08684 2/20 0.65
HPGD P15428 2/20 0.65
CISD1 Q9NZ45 1/20 0.65
SLC16A3 O15427 1/20 0.65
SLC16A1 P53985 1/20 0.65
GPR35 Q9HC97 1/20 0.65
EGFR P00533 1/20 0.65
CYP1A2 P05177 1/20 0.62
MAPT P10636 1/20 0.62
TSHR P16473 1/20 0.62
NFKB1 P19838 1/20 0.62
APEX1 P27695 1/20 0.62
BLM P54132 1/20 0.62
PMP22 Q01453 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL782092 1.00 ALDH1A1 (0.65) ALDH1A1KDM4ECYP3A4HPGDCISD1
SCHEMBL782091 1.00 ALDH1A1 (0.65) ALDH1A1KDM4ECYP3A4HPGDCISD1
SCHEMBL21625778 0.95 ALDH1A1 (0.59) ALDH1A1KDM4ECYP3A4HPGDCISD1
SCHEMBL21637629 0.95 ALDH1A1 (0.59) ALDH1A1KDM4ECYP3A4HPGDCISD1
SCHEMBL21625782 0.95 ALDH1A1 (0.59) ALDH1A1KDM4ECYP3A4HPGDCISD1
SCHEMBL7008415 0.88 SLC16A3 (0.57) ALDH1A1KDM4ECYP3A4HPGDCISD1
SCHEMBL28335121 0.88 SLC16A3 (0.67) ALDH1A1KDM4ECYP3A4HPGDCISD1
SCHEMBL17112792 0.88 KDM4E (0.64) ALDH1A1KDM4ECYP3A4HPGDCISD1
SCHEMBL17112791 0.88 KDM4E (0.64) ALDH1A1KDM4ECYP3A4HPGDCISD1
SCHEMBL13060202 0.88 MAPT (0.72) ALDH1A1KDM4ECYP3A4HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11802106-B2 Cathode buffer layer material and organic or organic/inorganic hybrid photoelectric device comprising same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2023-10-31 US claimed
US-20210198188-A1 NOVEL CATHODE BUFFER LAYER MATERIAL AND ORGANIC OR ORGANIC/INORGANIC HYBRID PHOTOELECTRIC DEVICE COMPRISING SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2021-07-01 US claimed
EP-1594880-B1 PHOTOPROTECTIVE COMPOSITIONS BASED ON METHYLTRIALKYLSILANES CONTAINING A CINNAMATE, CINNAMAMIDE, BENZALMALONAMIDE OR BENZALMALONATE FUNCTION OREAL (FR) 2008-03-19 EP claimed
EP-4067367-B1 OLEANANE CINNAMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF LUNAN PHARMACEUTICAL GROUP CORP (CN) 2025-05-28 EP disclosed
US-11802106-B2 Cathode buffer layer material and organic or organic/inorganic hybrid photoelectric device comprising same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2023-10-31 US disclosed
US-20230023332-A1 OLEAN-PHENYLACRYLAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF LUNAN PHARMACEUTICAL GROUP CORPORATION (CN) 2023-01-26 US disclosed
EP-4067367-A1 OLEANANE CINNAMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF Lunan Pharmaceutical Group Corporation (CN) 2022-10-05 EP disclosed
US-20210198188-A1 NOVEL CATHODE BUFFER LAYER MATERIAL AND ORGANIC OR ORGANIC/INORGANIC HYBRID PHOTOELECTRIC DEVICE COMPRISING SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2021-07-01 US disclosed
WO-2021104391-A1 OLEANANE CINNAMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 鲁南制药集团股份有限公司 2021-06-03 WO disclosed
EP-3515902-A1 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL Grünenthal GmbH (DE) 2019-07-31 EP disclosed
US-10265310-B2 6-membered cyclic amines or lactames substituted with urea and phenyl Grünenthal GmbH (DE) 2019-04-23 US disclosed
US-20040074012-A1 Method for providing textile material with uv protection BASF AKTIENGESELLSCHAFT (DE) 2004-04-22 US disclosed
EP-1383952-A2 METHOD FOR PROVIDING TEXTILE MATERIAL WITH UV PROTECTION BASF AKTIENGESELLSCHAFT (DE) 2004-01-28 EP disclosed
US-20030127633-A1 Uv absorbing mixture with textile fiber affinity BASF AKTIENGESELLSCHAFT (DE) 2003-07-10 US disclosed
EP-1267820-A2 UV-ABSORBING MIXTURE WITH TEXTILE FIBRE AFFINITY BASF AKTIENGESELLSCHAFT (DE) 2003-01-02 EP disclosed
WO-2002063091-A2 METHOD FOR PROVIDING TEXTILE MATERIAL WITH UV PROTECTION BASF AKTIENGESELLSCHAFT (DE) 2002-08-15 WO disclosed
WO-2001072935-A2 UV-ABSORBING MIXTURE WITH TEXTILE FIBRE AFFINITY BASF AKTIENGESELLSCHAFT (DE) 2001-10-04 WO disclosed
EP-1126833-A2 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2001-08-29 EP disclosed
EP-0901512-B1 DETERGENT COMPOSITION UNILEVER PLC (GB) 2000-06-21 EP disclosed
WO-2000025768-A1 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2000-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023332-A1 OLEAN-PHENYLACRYLAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF PAOX, ALOX12, PNMT ALDH1A1 418/4885KDM4E 991/4885CYP3A4 163/4885
US-11802106-B2 Cathode buffer layer material and organic or organic/inorganic hybrid photoelectric device comprising same DCX, CDH1, CACNA2D3 ALDH1A1 3065/4885KDM4E 1369/4885CYP3A4 3086/4885
US-20210198188-A1 NOVEL CATHODE BUFFER LAYER MATERIAL AND ORGANIC OR ORGANIC/INORGANIC HYBRID PHOTOELECTRIC DEVICE COMPRISING SAME DCX, HCN3, CDH1 ALDH1A1 3167/4885KDM4E 1555/4885CYP3A4 3511/4885
US-10265310-B2 6-membered cyclic amines or lactames substituted with urea and phenyl FPR2, FPR1, FPR3 ALDH1A1 3156/4885KDM4E 4525/4885CYP3A4 2271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.