Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL4014871 | 0.79 | MEN1 (0.44) | NR4A1MEN1KMT2A | |
| SCHEMBL4999732 | 0.77 | MEN1 (0.35) | MEN1KMT2A | |
| Potassium Ion SCHEMBL14695214 | 0.70 | MEN1 (0.43) | MEN1KMT2A | |
| Potassium Ion SCHEMBL29727670 | 0.66 | LMNA (0.41) | MEN1KMT2A | |
| Potassium Ion SCHEMBL224967 | 0.66 | LMNA (0.41) | MEN1KMT2A | |
| SCHEMBL29329231 | 0.65 | ALDH1A1 (0.41) | MEN1KMT2A | |
| SCHEMBL2721232 | 0.62 | LMNA (0.44) | MEN1KMT2A | |
| SCHEMBL11852597 | 0.60 | G6PD (0.38) | MEN1KMT2A | |
| SCHEMBL101050 | 0.60 | MEN1 (0.49) | MEN1KMT2A | |
| Potassium Ion SCHEMBL338797 | 0.57 | KMT2A (0.44) | NR4A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7411068-B2 | Luminescent compounds | SETA BIOMEDICALS, LLC | 2008-08-12 | — | — | US | disclosed |
| US-20050202565-A1 | Luminescent compounds | SETA BIOMEDICALS, LLC | 2005-09-15 | — | — | US | disclosed |