SCHEMBL50008

SCHEMBL50008

Cn1sc2ccccc2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 7/20 1.00
G6PD P11413 4/20 1.00
PMM2 O15305 5/20 0.55
MPI P34949 5/20 0.55
PHOSPHO1 Q8TCT1 5/20 0.55
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.55
MAPT P10636 2/20 0.55
PKM P14618 2/20 0.55
HPGD P15428 2/20 0.55
ALOX12 P18054 2/20 0.55
NPSR1 Q6W5P4 2/20 0.55
APOBEC3G Q9HC16 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
HSP90AA1 P07900 1/20 0.55
NPC1 O15118 1/20 0.53
TP53 P04637 1/20 0.53
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
KDM5B Q9UGL1 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL16222837 0.98 CASP3 (0.96) CASP3G6PDPMM2MPIPHOSPHO1
SCHEMBL16916878 0.81 CASP3 (0.83) CASP3G6PDFAAHMGLL
SCHEMBL11278746 0.77 CASP3 (0.74) CASP3G6PDFAAHMGLL
SCHEMBL358740 0.75 FAAH (0.77) CASP3G6PDFAAHMGLL
SCHEMBL929806 0.74 CASP3 (0.59) CASP3G6PDPMM2MPIPHOSPHO1
SCHEMBL27971811 0.74 CASP3 (0.59) CASP3G6PDPMM2MPIPHOSPHO1
SCHEMBL10833396 0.74 CASP3 (0.59) CASP3G6PDPMM2MPIPHOSPHO1
SCHEMBL26831734 0.74 CASP3 (0.59) CASP3G6PDPMM2MPIPHOSPHO1
SCHEMBL18913134 0.74 CASP3 (0.59) CASP3G6PDPMM2MPIPHOSPHO1
SCHEMBL2371018 0.74 CASP3 (0.59) CASP3G6PDPMM2MPIPHOSPHO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1461 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026041525-A1 AQUEOUS ADHESIVE COMPOSITIONS STABILIZED AGAINST MICROBIAL INFESTATION THOR GMBH (DE) 2026-02-26 WO claimed
WO-2026041529-A1 AQUEOUS COMPOSITIONS OF AGRICULTURAL CHEMICALS STABILIZED AGAINST MICROBIAL INFESTATION THOR GMBH (DE) 2026-02-26 WO claimed
US-20260035753-A1 METHODS OF DETERMINING BACTERIA AND MANUFACTURING A FIBROUS WEB AND TOOLS AND USES RELATED THERETO KEMIRA OYJ (FI) 2026-02-05 US claimed
WO-2025125110-A1 GUANIDINE- AND CARBONATE-CONTAINING COMPOSITIONS THOR GMBH (DE) 2025-06-19 WO claimed
US-20250172003-A1 WALL FINISHING SYSTEM DUROCK ALFACING INTERNATIONAL LIMITED (CA) 2025-05-29 US claimed
CN-119867078-A Isothiazole compound bactericide and preparation method and application thereof 四川环科青绿科技有限公司 2025-04-25 CN claimed
WO-2025082321-A1 MOLD-PROOF POLYURETHANE COMPOSITION, AND PREPARATION METHOD THEREFOR AND USE THEREOF SIKA技术股份公司 2025-04-24 WO claimed
CN-119859233-A Mildew-proof polyurethane composition, and preparation method and application thereof SIKA技术股份公司 2025-04-22 CN claimed
EP-4516862-A1 AQUEOUS COATING COMPOSITION, COATING OBTAINED FROM THE COATING COMPOSITION, SUBSTRATE CONTAINING THE COATING AND THE USE OF THE AQUEOUS COATING COMPOSITION DAW SE (DE) 2025-03-05 EP claimed
CN-119504635-A Method for preparing 2-methyl benzisothiazolin-3-one at room temperature by using NCS 常州大学 2025-02-25 CN claimed
US-20040198785-A1 Microbicidal composition DDP SPECIALTY ELECTRONIC MATERIALS US 8, LLC 2004-10-07 US claimed
EP-1462003-A1 Microbiocidal composition ROHM AND HAAS COMPANY (US) 2004-09-29 EP claimed
US-20040058952-A1 Urease inhibitors OTSUKA PHARMACEUTICAL CO., LTD. 2004-03-25 US claimed
EP-1315419-A1 SYNERGETIC BIOCIDAL COMPOSITION COMPRISING 2-METHYLISOTHIAZOLINE-3-ON THOR GmbH (DE) 2003-06-04 EP claimed
US-20030060482-A1 Urease inhibitors OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2003-03-27 US claimed
EP-1262181-A1 UREASE INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2002-12-04 EP claimed
WO-2002017716-A1 SYNERGETIC BIOCIDAL COMPOSITION COMPRISING 2-METHYLISOTHIAZOLINE-3-ON THOR GMBH (DE) 2002-03-07 WO claimed
EP-0755392-A4 ALPHA1C ADRENERGIC RECEPTOR ANTAGONISTS MERCK & CO INC (US) 1997-05-02 EP claimed
EP-0755392-A1 ALPHA1C ADRENERGIC RECEPTOR ANTAGONISTS MERCK & CO. INC. (US) 1997-01-29 EP claimed
WO-1995028397-A1 ALPHA1C ADRENERGIC RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1995-10-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030060482-A1 Urease inhibitors PGC, SLC14A1, USP1 CASP3 2704/4885G6PD 124/4885PMM2 3405/4885
US-20040198785-A1 Microbicidal composition TLR2, FABP2, TLR1 CASP3 1223/4885G6PD 1809/4885PMM2 3941/4885
US-20260035753-A1 METHODS OF DETERMINING BACTERIA AND MANUFACTURING A FIBROUS WEB AND TOOLS AND USES RELATED THERETO POLL, UROD, RNGTT CASP3 3259/4885G6PD 1010/4885PMM2 187/4885
US-20040058952-A1 Urease inhibitors PGC, SLC14A1, USP1 CASP3 2704/4885G6PD 124/4885PMM2 3405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.