Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5301480 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDTSHRNPSR1 | |
| SCHEMBL24300151 | 0.80 | ALDH1A1 (0.56) | ALDH1A1LMNACYP2C9TSHRALOX15 | |
| SCHEMBL15148197 | 0.79 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HPGDTSHRALOX15 | |
| SCHEMBL27269817 | 0.79 | TYR (0.42) | TYRALDH1A1S1PR1LMNASMN1; SMN2 | |
| SCHEMBL5431004 | 0.79 | DHFR (0.46) | TYRALDH1A1S1PR1LMNASMN1; SMN2 | |
| SCHEMBL346292 | 0.79 | ALDH1A1 (0.61) | TYRALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL18627679 | 0.79 | IDO1 (0.43) | TYRALDH1A1LMNASMN1; SMN2PYCR1 | |
| Hydrochloric Acid SCHEMBL15018375 | 0.78 | ALDH1A1 (0.54) | ALDH1A1LMNACYP2C9TSHRALOX15 | |
| Hydrochloric Acid SCHEMBL2861214 | 0.77 | ALDH1A1 (0.58) | TYRALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL12204911 | 0.77 | ALDH1A1 (0.55) | ALDH1A1LMNAHTTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | AUTOTAC INC. (KR) | 2023-06-08 | — | — | US | disclosed |
| US-20230028318-A1 | FLUOROGENIC AMINO ACIDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-01-26 | — | — | US | disclosed |
| US-20210040058-A1 | ACID-LABILE SURFACTANTS | PROMEGA CORPORATION | 2021-02-11 | — | — | US | disclosed |
| US-20200181101-A1 | BENZAMIDE INHIBITORS OF BACTERIAL LIPOPROTEIN SIGNAL PEPTIDASE | SCRIPPS RESEARCH INST (US) | 2020-06-11 | — | — | US | disclosed |
| US-10208000-B2 | Eis inhibitors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2019-02-19 | — | — | US | disclosed |
| US-20170174639-A1 | EIS INHIBITORS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2017-06-22 | — | — | US | disclosed |
| US-8178490-B2 | Polybasic bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174639-A1 | EIS INHIBITORS | ABCC1, ATP5ME, ABCG2 | TYR 3680/4885ALDH1A1 819/4885S1PR1 3659/4885 |
| US-20200181101-A1 | BENZAMIDE INHIBITORS OF BACTERIAL LIPOPROTEIN SIGNAL PEPTIDASE | LPL, LIPE, LYPLA2 | TYR 3758/4885ALDH1A1 3104/4885S1PR1 2679/4885 |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCB1, SLC47A1 | TYR 4753/4885ALDH1A1 4062/4885S1PR1 3764/4885 |
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | UBR4, UBQLN2, UBTF | TYR 3973/4885ALDH1A1 2317/4885S1PR1 3777/4885 |
| US-20210040058-A1 | ACID-LABILE SURFACTANTS | SMURF1, S100A6, SPAST | TYR 4737/4885ALDH1A1 4483/4885S1PR1 1084/4885 |
| US-10208000-B2 | Eis inhibitors | ABCC1, ATP5ME, ABCG2 | TYR 3680/4885ALDH1A1 819/4885S1PR1 3659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.