Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1L | O00429 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047187 | 0.87 | HDAC3 (0.36) | ACHEALDH1A1HSD17B10MGLLCTSK | |
| SCHEMBL5044496 | 0.85 | ATP4A (0.37) | MGLLCTSK | |
| SCHEMBL5044606 | 0.85 | HTR2A (0.44) | DNM1LHPGD | |
| SCHEMBL5047889 | 0.85 | MGLL (0.36) | MGLLCTSK | |
| SCHEMBL5043850 | 0.84 | NCEH1 (0.41) | ALDH1A1HSD17B10FAAHCTSK | |
| SCHEMBL5044102 | 0.84 | MAPT (0.40) | ALDH1A1HPGD | |
| SCHEMBL5047653 | 0.84 | ATP4A (0.38) | ACHEMGLL | |
| SCHEMBL5040330 | 0.84 | NTMT1 (0.40) | MGLLFAAH | |
| SCHEMBL5048696 | 0.84 | CDC25A (0.43) | ALDH1A1MGLLFAAHHPGD | |
| SCHEMBL5047174 | 0.83 | CNR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583762-B1 | PYRROLYL-THIAZOLES AND THEIR USE AS CB 1 RECEPTOR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-09 | — | — | EP | claimed |