Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047944 | 0.86 | DRD2 (0.46) | NAAASMN1; SMN2NPC1LMNATP53 | |
| SCHEMBL5047987 | 0.85 | PTGS2 (0.41) | NAAASMN1; SMN2NPC1LMNATP53 | |
| SCHEMBL6022152 | 0.80 | DRD2 (0.43) | NAAASMN1; SMN2NPC1LMNATP53 | |
| SCHEMBL5044591 | 0.79 | LTA4H (0.46) | NPC1RAB9A | |
| SCHEMBL1854176 | 0.76 | NAAA (0.40) | NAAANPC1RAB9AASAH1DRD2 | |
| SCHEMBL5655239 | 0.73 | NAAA (0.54) | NAAASMN1; SMN2LMNAL3MBTL1MLYCD | |
| SCHEMBL5045572 | 0.73 | ALDH1A1 (0.49) | NAAASMN1; SMN2L3MBTL1MLYCDHDAC1 | |
| SCHEMBL5045562 | 0.71 | ALDH1A1 (0.47) | NAAASMN1; SMN2PTGS2DRD2DRD4 | |
| SCHEMBL5044168 | 0.71 | ALDH1A1 (0.47) | NAAASMN1; SMN2PTGS2DRD2DRD4 | |
| SCHEMBL5044228 | 0.71 | NAMPT (0.46) | NAAASMN1; SMN2L3MBTL1MLYCDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |