Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623819 | 0.77 | ADRB2 (0.41) | ALDH1A1GAANISCHCNR1ADRB2 | |
| SCHEMBL266714 | 0.73 | LMNA (0.43) | ALDH1A1NPSR1LMNAMAPTKMT2A | |
| SCHEMBL9630544 | 0.72 | ACP3 (0.41) | ALDH1A1GAACNR1CASP1ADRB2 | |
| SCHEMBL8378871 | 0.71 | CASP1 (0.46) | ALDH1A1NISCHCNR1CASP1ADRB2 | |
| SCHEMBL9341404 | 0.70 | ALDH1A1 (0.39) | ALDH1A1GAACNR1ADRB2HIF1A | |
| SCHEMBL11189703 | 0.70 | ALDH1A1 (0.31) | ALDH1A1GAACYP2D6NFKB1NPSR1 | |
| SCHEMBL9337776 | 0.70 | HSD17B10 (0.43) | ALDH1A1CYP2D6LMNAHTT | |
| SCHEMBL2632968 | 0.70 | NISCH (0.47) | NISCHCNR1CASP1ADRB2ADRB1 | |
| SCHEMBL28592536 | 0.69 | GPR84 (0.59) | GAACYP2D6NPSR1MAPTKMT2A | |
| SCHEMBL3789761 | 0.69 | TSHR (0.59) | ALDH1A1NISCHCASP1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11712680-B2 | Process for reducing aromatic nitro compounds with supported catalyst | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2023-08-01 | — | — | US | disclosed |
| US-20220401927-A1 | PROCESS FOR REDUCING AROMATIC NITRO COMPOUNDS WITH SUPPORTED CATALYST | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-12-22 | — | — | US | disclosed |
| US-11452992-B2 | Iron oxide supported rhodium catalyst for nitroarene reduction | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-09-27 | — | — | US | disclosed |
| US-20200298212-A1 | IRON OXIDE SUPPORTED RHODIUM CATALYST FOR NITROARENE REDUCTION | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2020-09-24 | — | — | US | disclosed |
| US-7425520-B2 | Catalyst for selective hydrogenation of nitro groups of halonitro aromatic compounds | HEADWATERS TECHNOLOGY INNOVATION, LLC (US) | 2008-09-16 | — | — | US | disclosed |
| US-20080033193-A1 | CATALYST FOR SELECTIVE HYDROGENATION OF NITRO GROUPS OF HALONITRO AROMATIC COMPOUNDS | HEADWATERS TECHNOLOGY INNOVATION, LLC (US) | 2008-02-07 | — | — | US | disclosed |
| US-7288500-B2 | Selective hydrogenation of nitro groups of halonitro aromatic compounds | HEADWATERS TECHNOLOGY INNOVATION, LLC (US) | 2007-10-30 | — | — | US | disclosed |
| US-20070049772-A1 | Selective hydrogenation of nitro groups of halonitro aromatic compounds | HEADWATERS HEAVY OIL, LLC | 2007-03-01 | — | — | US | disclosed |
| EP-0842920-B1 | Process for the production of aromatic halogen-amino compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2004-04-07 | — | — | EP | disclosed |
| US-6197716-B1 | AS HYDROGENATION CATALYST IN HYDROGENATION OF AROMATIC HALONITRO COMPOUNDS TO AROMATIC HALOAMINO COMPOUNDS | NOVARTIS AG (CH) | 2001-03-06 | — | — | US | disclosed |
| US-5962741-A | Process for the production of aromatic halogen-amino compounds | NOVARTIS AG (CH) | 1999-10-05 | — | — | US | disclosed |
| EP-0842920-A2 | Process for the production of aromatic halogen-amino compounds | Novartis AG (CH) | 1998-05-20 | — | — | EP | disclosed |
| US-4020107-A | ACIDIC PHOSPHORUS COMPOUND DEHALOGENATION INHIBITOR | E. I. DU PONT DE NEMOURS AND CO. (US) | 1977-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11712680-B2 | Process for reducing aromatic nitro compounds with supported catalyst | ARG2, NDUFS5, NDUFS7 | ALDH1A1 2712/4885GAA 1040/4885NISCH 21/4885 |
| US-20220401927-A1 | PROCESS FOR REDUCING AROMATIC NITRO COMPOUNDS WITH SUPPORTED CATALYST | ARG2, NDUFS5, NDUFS7 | ALDH1A1 2712/4885GAA 1040/4885NISCH 21/4885 |
| US-11452992-B2 | Iron oxide supported rhodium catalyst for nitroarene reduction | ARG2, NOS2, NDUFS7 | ALDH1A1 2798/4885GAA 1858/4885NISCH 56/4885 |
| US-20200298212-A1 | IRON OXIDE SUPPORTED RHODIUM CATALYST FOR NITROARENE REDUCTION | ARG2, NOS2, NDUFS7 | ALDH1A1 2798/4885GAA 1858/4885NISCH 56/4885 |
| US-20070049772-A1 | Selective hydrogenation of nitro groups of halonitro aromatic compounds | NOXO1, PYM1, HCN4 | ALDH1A1 3031/4885GAA 4752/4885NISCH 178/4885 |
| US-20080033193-A1 | CATALYST FOR SELECTIVE HYDROGENATION OF NITRO GROUPS OF HALONITRO AROMATIC COMPOUNDS | PYM1, NOXO1, SCO2 | ALDH1A1 3025/4885GAA 4626/4885NISCH 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.