Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | BRD1 | O95696 | 1/20 | 0.38 |
| ▸ | TAF1 | P21675 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533384 | 0.81 | ALDH1A1 (0.48) | L3MBTL1PTPN1NPC1POLBNOTUM | |
| SCHEMBL1097070 | 0.77 | HTR6 (0.50) | MAPTL3MBTL1HTTPTPN1BRD1 | |
| SCHEMBL29627850 | 0.73 | NOTUM (0.50) | MAPTL3MBTL1PTPN1TSHRNOTUM | |
| SCHEMBL28691758 | 0.72 | NOTUM (0.49) | MAPTL3MBTL1PTPN1TSHRNOTUM | |
| SCHEMBL9178263 | 0.71 | ALDH1A1 (0.50) | MAPTL3MBTL1HTTGRM5NPC1 | |
| SCHEMBL3084334 | 0.70 | NPC1 (0.68) | SMARCA2SMARCA4PBRM1MAPTHTT | |
| SCHEMBL17040205 | 0.70 | ALDH1A1 (0.60) | MAPTL3MBTL1PTPN1FOLH1POLB | |
| SCHEMBL3057279 | 0.69 | L3MBTL1 (0.58) | MAPTL3MBTL1CFTRNPC1RAB9A | |
| SCHEMBL21891709 | 0.68 | CPB1 (0.68) | L3MBTL1GRM5RAB9ATSHRKMT2A | |
| SCHEMBL6829549 | 0.68 | NOTUM (0.51) | L3MBTL1PTPN1NPC1POLBNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051386-A1 | Tricyclic Pyrazole Derivatives as Cannabinoid Receptor Modulators | CADILA HEALTHCARE LIMITED (IN) | 2008-02-28 | — | — | US | claimed |
| US-20080051386-A1 | Tricyclic Pyrazole Derivatives as Cannabinoid Receptor Modulators | CADILA HEALTHCARE LIMITED (IN) | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051386-A1 | Tricyclic Pyrazole Derivatives as Cannabinoid Receptor Modulators | CNR2, CNR1, GPR55 | SMARCA2 4154/4885SMARCA4 3795/4885PBRM1 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.