Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5081250 | 0.79 | HRH1 (0.37) | ALDH1A1KDM4EKMT2AMEN1PKM | |
| SCHEMBL5139533 | 0.75 | RAB9A (0.38) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| Bromide SCHEMBL11733192 | 0.74 | SMN1; SMN2 (0.37) | ALDH1A1KMT2AMEN1PKMRAB9A | |
| SCHEMBL28393356 | 0.70 | TDP1 (0.39) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL5077937 | 0.70 | MAPT (0.45) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL5074722 | 0.70 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1POLBPKM | |
| Hydrochloric Acid SCHEMBL11734144 | 0.69 | TDP1 (0.41) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL5073994 | 0.67 | LMNA (0.36) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL28298086 | 0.67 | GPR35 (0.36) | ALDH1A1RAB9ALMNAL3MBTL1 | |
| SCHEMBL13075738 | 0.66 | ALDH1A1 (0.55) | ALDH1A1KDM4ECTSBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001474-A2 | BICYCLOHETEROARYL COMPOUNDS AS P2X7 MODULATORS AND USES THEREOF | Renovis, Inc. (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007109172-A2 | BICYCLOHETEROARYL COMPOUNDS AS P2X7 MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2007-09-27 | — | — | WO | disclosed |