Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2552936 | 0.88 | PTGS2 (0.54) | AKR1B1GABRA1GABRB2TDP1PTGS2 | |
| SCHEMBL27907594 | 0.86 | AKR1B1 (0.71) | AKR1B1GABRA1GABRB2PTGS2MEN1 | |
| SCHEMBL29101379 | 0.86 | AKR1B1 (0.46) | AKR1B1GABRA1GABRB2TDP1PTGS2 | |
| SCHEMBL8189339 | 0.86 | AKR1B1 (0.46) | AKR1B1GABRA1GABRB2TDP1PTGS2 | |
| SCHEMBL1873283 | 0.86 | AKR1B1 (0.60) | AKR1B1TDP1PTGS2DUSP3PTPN5 | |
| Benzene SCHEMBL1146112 | 0.86 | AKR1B1 (0.60) | AKR1B1TDP1PTGS2DUSP3PTPN5 | |
| SCHEMBL2392464 | 0.83 | PTGDR2 (0.50) | AKR1B1TDP1PTGS2DUSP3PTPN5 | |
| SCHEMBL29010053 | 0.82 | AKR1B1 (0.42) | AKR1B1GABRA1GABRB2TDP1PTGS2 | |
| SCHEMBL8172704 | 0.82 | FBP1 (0.49) | AKR1B1TDP1MEN1KMT2ATSHR | |
| SCHEMBL2820614 | 0.80 | GABRA1 (0.48) | GABRA1GABRB2GAAPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691938-B2 | Process for preparing 2,6-dialkylphenylacetic acids | BAYER AKTIENGESELLSCHAFT (DE) | 2023-07-04 | — | — | US | disclosed |
| US-20210403406-A1 | PROCESS FOR PREPARING 2,6-DIALKYLPHENYLACETIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-30 | — | — | US | disclosed |
| CN-112004795-A | Process for preparing 2, 6-dialkylphenylacetic acid | 拜耳公司 | 2020-11-27 | — | — | CN | disclosed |
| EP-2406216-B1 | HALOGENALKYLMETHYLENOXY-PHENYL-SUBSTITUTED KETOENOLS | BAYER IP GMBH (DE) | 2017-04-19 | — | — | EP | disclosed |
| EP-3153503-A1 | INTERMEDIATES FOR HALOGENOALKYLMETHYLENOXY-PHENYL-SUBSTITUTED KETOENOLS | Bayer Intellectual Property GmbH (DE) | 2017-04-12 | — | — | EP | disclosed |
| US-9096534-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-08-04 | — | — | US | disclosed |
| US-9096533-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-08-04 | — | — | US | disclosed |
| US-9045390-B2 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | BAYER CROPSCIENCE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-20150126738-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2015-05-07 | — | — | US | disclosed |
| US-20150126739-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2015-05-07 | — | — | US | disclosed |
| US-20100248964-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-30 | — | — | US | disclosed |
| WO-2010102758-A2 | HALOGENALKYLMETHYLENOXY-PHENYL-SUBSTITUTED KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2010-09-16 | — | — | WO | disclosed |
| US-20100210462-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-08-19 | — | — | US | disclosed |
| EP-1280770-B1 | C 2? PHENYL-SUBSTITUTED CYCLIC KETO-ENOLS USED AS PESTICIDES AND HERBICIDES | BAYER AG (DE) | 2010-06-23 | — | — | EP | disclosed |
| EP-2187745-A2 | HERBICIDAL COMPOSITION | Sumitomo Chemical Company, Limited (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-1996557-B1 | PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES | SUMITOMO CHEMICAL CO (JP) | 2010-03-03 | — | — | EP | disclosed |
| US-20090111696-A1 | Pyridazinone Compound and Use Thereof as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| WO-2009035151-A2 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | WO | disclosed |
| EP-1996557-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES | Sumitomo Chemical Company, Limited (JP) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007119434-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403406-A1 | PROCESS FOR PREPARING 2,6-DIALKYLPHENYLACETIC ACIDS | ADH1C, ADH1A, ADH5 | AKR1B1 174/4885GABRA1 688/4885GABRB2 336/4885 |
| US-20100248964-A1 | HERBICIDAL COMPOSITION | CHRM2, CHRM1, WEE1 | AKR1B1 536/4885GABRA1 2899/4885GABRB2 2575/4885 |
| US-20150126738-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | PDXK, PLPBP, PNPO | AKR1B1 600/4885GABRA1 2393/4885GABRB2 2358/4885 |
| US-20100210462-A1 | HERBICIDAL COMPOSITION | WEE1, WEE2, H1-3 | AKR1B1 936/4885GABRA1 1522/4885GABRB2 1736/4885 |
| US-20150126739-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | PDXK, PLPBP, PNPO | AKR1B1 600/4885GABRA1 2393/4885GABRB2 2358/4885 |
| US-11691938-B2 | Process for preparing 2,6-dialkylphenylacetic acids | ADH1C, ADH1A, ADH5 | AKR1B1 174/4885GABRA1 688/4885GABRB2 336/4885 |
| US-20090111696-A1 | Pyridazinone Compound and Use Thereof as herbicides | PDXK, DDT, PLPBP | AKR1B1 486/4885GABRA1 2022/4885GABRB2 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.