Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS known ✓ | P04818 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 3/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.45 |
| ▸ | CCND1 | P24385 | 3/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
| ▸ | CDK7 | P50613 | 3/20 | 0.45 |
| ▸ | CCNH | P51946 | 3/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.45 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | S100A9 | P06702 | 4/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11760740 | 0.96 | PKM (0.50) | PKMCDK1CCNB1CCNA2CCND1 | |
| Potassium Ion SCHEMBL11757835 | 0.96 | PKM (0.50) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL388032 | 0.77 | PKM (0.53) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL6038652 | 0.76 | PKM (0.52) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL301846 | 0.76 | PKM (0.52) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL1645094 | 0.76 | PKM (0.52) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL12560498 | 0.76 | PKM (0.52) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL11757841 | 0.74 | PKM (0.50) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL5137127 | 0.74 | PKM (0.50) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL8630771 | 0.74 | PKM (0.50) | PKMCDK1CCNB1CCNA2CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113025019-A | High-heat-resistance flame-retardant polycarbonate composite material and preparation method thereof | 上海杰事杰新材料(集团)股份有限公司 | 2021-06-25 | — | — | CN | claimed |
| US-4039509-A | METAL SALTS OF HETEROCYCLIC SULFONIC ACIDS | GENERAL ELECTRIC COMPANY (US) | 1977-08-02 | — | — | US | claimed |
| EP-4130152-A1 | GLASS-FIBER-CONTAINING FLAME-RETARDANT POLYCARBONATE RESIN COMPOSITION AND MOLDED OBJECT | ADEKA CORPORATION (JP) | 2023-02-08 | — | — | EP | disclosed |
| CN-115362213-A | Flame-retardant polycarbonate resin composition containing glass fiber and molded article | 株式会社ADEKA | 2022-11-18 | — | — | CN | disclosed |
| CN-113025019-A | High-heat-resistance flame-retardant polycarbonate composite material and preparation method thereof | 上海杰事杰新材料(集团)股份有限公司 | 2021-06-25 | — | — | CN | disclosed |
| EP-1497374-B1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GEN ELECTRIC (US) | 2008-08-13 | — | — | EP | disclosed |
| US-7244778-B2 | Filler reinforced polyether imide resin composition and molded article thereof | GENERAL ELECTRIC COMPANY (US) | 2007-07-17 | — | — | US | disclosed |
| CN-1314761-C | Filler reinforced polyether imide resin composition and molded article thereof | GEN ELECTRIC (US) | 2007-05-09 | — | — | CN | disclosed |
| CN-1659234-A | filler-reinforced polyetherimide resin composition and molded article thereof | GEN ELECTRIC (US) | 2005-08-24 | — | — | CN | disclosed |
| US-20050131105-A1 | Filler reinforced polyether imide resin composition and molded article thereof | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2005-06-16 | — | — | US | disclosed |
| EP-1497374-A1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GENERAL ELECTRIC COMPANY (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-0127818-A1 | Improved flame retardant polycarbonate compositions | GENERAL ELECTRIC COMPANY (US) | 1984-12-12 | — | — | EP | disclosed |
| US-4469833-A | MINOR AMOUNTS FO THIODIPHENOL AND ORGANIC SULFONATE | GENERAL ELECTRIC COMPANY (US) | 1984-09-04 | — | — | US | disclosed |
| US-4454275-A | Flame retardant copolyester-carbonate compositions | GENERAL ELECTRIC COMPANY (US) | 1984-06-12 | — | — | US | disclosed |
| EP-0103123-A1 | Flame retardant copolyester-carbonate compositions | GENERAL ELECTRIC COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4391935-A | Flame retardant polycarbonate composition | GENERAL ELECTRIC COMPANY (US) | 1983-07-05 | — | — | US | disclosed |
| WO-1982002895-A1 | FLAME RETARDANT POLYESTER-CARBONATE COMPOSITIONS | GEN ELECTRIC (US) | 1982-09-02 | — | — | WO | disclosed |
| US-4220583-A | CONTAINING PARTIALLY FLUORINATED POLYOLEFIN AND ALKALI METAL SULFONATE | GENERAL ELECTRIC COMPANY (US) | 1980-09-02 | — | — | US | disclosed |
| US-4197232-A | Flame retardant polycarbonate composition | GENERAL ELECTRIC COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-3971756-A | SILOXANE, ORGANIC ALKALI OR ALKALINE EARTH SALTS | GENERAL ELECTRIC COMPANY (US) | 1976-07-27 | — | — | US | disclosed |