SCHEMBL5146133

SCHEMBL5146133

O=S(=O)(c1ccccc1)c1[c]cccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.46
ALDH1A1 P00352 6/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HSD11B1 P28845 3/20 0.38
KIF18A Q8NI77 1/20 0.37
KMT2A Q03164 4/20 0.36
HTT P42858 2/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
TSHR P16473 2/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA3 P07451 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4783755 0.78 HTR6 (0.53) HTR6ALDH1A1HSD17B10TDP1KMT2A
SCHEMBL691617 0.76 ALDH1A1 (0.35) ALDH1A1HSD17B10TDP1KMT2ALMNA
SCHEMBL5510889 0.75 KEAP1 (0.48) ALDH1A1KMT2AMAPTCA12CA1
SCHEMBL11692937 0.75 TSHR (0.45) HTR6ALDH1A1HSD11B1KMT2AHTT
SCHEMBL5510640 0.75 CA1 (0.35) ALDH1A1TDP1KMT2ALMNACA12
SCHEMBL1828766 0.75 HSD11B1 (0.33) ALDH1A1TDP1HSD11B1KMT2ALMNA
SCHEMBL28690137 0.74 HTR6 (0.57) HTR6HSD17B10KMT2ALMNAMAPT
SCHEMBL516500 0.70 HSD11B1 (0.67) HTR6ALDH1A1HSD17B10TDP1HSD11B1
SCHEMBL315684 0.68 HTR6 (0.54) HTR6ALDH1A1HSD17B10TDP1KMT2A
(Phenylsulfonyl)Benzene SCHEMBL10611758 0.68 ALDH1A1 (0.73) HTR6ALDH1A1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7288360-B2 Image recording material FUJIFILM CORPORATION (JP) 2007-10-30 US disclosed
US-20040214104-A1 Image recording material FUJI PHOTO FILM CO., LTD. 2004-10-28 US disclosed