Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 5/20 | 0.42 |
| ▸ | CA2 known ✓ | P00918 | 5/20 | 0.42 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.63 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | PLEC | Q15149 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30118451 | 1.00 | PTPN1 (0.63) | PTPN1APEX1SIRT1PRMT1DUSP5 | |
| SCHEMBL29516436 | 0.85 | APEX1 (0.64) | PTPN1APEX1PRMT1CASP6CA1 | |
| SCHEMBL29575995 | 0.85 | APEX1 (0.64) | PTPN1APEX1PRMT1CASP6CA1 | |
| SCHEMBL1413179 | 0.85 | APEX1 (0.64) | PTPN1APEX1PRMT1CASP6CA1 | |
| SCHEMBL8010537 | 0.84 | APEX1 (0.63) | PTPN1APEX1PRMT1CASP6CA1 | |
| SCHEMBL5147103 | 0.84 | APEX1 (0.63) | PTPN1APEX1PRMT1CASP6CA1 | |
| SCHEMBL9411862 | 0.80 | APEX1 (0.77) | PTPN1APEX1SIRT1PRMT1DUSP5 | |
| Chromotropate SCHEMBL564557 | 0.79 | PTPN1 (1.00) | PTPN1APEX1SIRT1PRMT1DUSP5 | |
| SCHEMBL11589914 | 0.78 | APEX1 (0.59) | PTPN1APEX1SIRT1PRMT1DUSP5 | |
| SCHEMBL2618015 | 0.77 | APEX1 (0.55) | PTPN1APEX1PRMT1CASP6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116790136-B | Carboxylic acid succinimide ester dye and reactive dyeing method thereof | 现代纺织技术创新中心(鉴湖实验室) | 2024-04-02 | — | — | CN | disclosed |
| CN-116790136-A | Carboxylic acid succinimide ester dye and reactive dyeing method thereof | 现代纺织技术创新中心(鉴湖实验室) | 2023-09-22 | — | — | CN | disclosed |
| US-7205083-B2 | Recording material | FUJIFILM CORPORATION (JP) | 2007-04-17 | — | — | US | disclosed |
| EP-1253466-B1 | Diazonium salt and heat-sensitive recording material | FUJI PHOTO FILM CO LTD (JP) | 2006-05-31 | — | — | EP | disclosed |
| US-6919159-B2 | Photopolymerizable composition and recording material using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2005-07-19 | — | — | US | disclosed |
| US-6824953-B2 | POLYMERIZABLE COMPOUND HAVING AN ETHYLENIC UNSATURATED BOND, A METHINE DYE, AND A RADICAL GENERATOR THAT INTERACTS WITH THE DYE TO GENERATE A RADICAL | FUJI PHOTO FILM CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-6767861-B2 | HEAT-SENSITIVE RECORDING LAYER AND AN ACETYLENE GLYCOL PROTECTIVE LAYER ON A SUPPORT | FUJI PHOTO FILM CO., LTD. (JP) | 2004-07-27 | — | — | US | disclosed |
| US-6749908-B2 | LAMINATES/TRANSPARENCIES FOR OVERHEAD PROJECTORS | FUJI PHOTO FILM CO., LTD. (JP) | 2004-06-15 | — | — | US | disclosed |
| US-6740466-B1 | HIGH SENSITIVITY TO UV, VISIBLE, ANDINFRARED; FOGGING OF THE BACKGROUND IS REDUCED; CLARITY AND HIGH CONTRAST; ADDITION POLYMERIZABLE COMPOUND, AN INDOLE-PYRIMIDINETRIONE METHINE DYE, AN ANIONIC ORGANOBORON COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 2004-05-25 | — | — | US | disclosed |
| US-20040082472-A1 | Recording material | FUJI PHOTO FILM CO., LTD. | 2004-04-29 | — | — | US | disclosed |
| US-6248497-B1 | LIGHT SENSITIVE AND HEAT SENSITIVE RECORDING IMAGES | FUJI PHOTO FILM CO., LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| US-6245476-B1 | SUPPORTS WITH DIAZO COMPOUNDS IN MICROCAPSULES | FUJI PHOTO FILM CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |
| US-6060206-A | Photo- and heat-sensitive recording material and colorant produced from the material | FUJI PHOTO FILM CO., LTD. (JP) | 2000-05-09 | — | — | US | disclosed |
| US-6017672-A | MIXTURE OF DIAZONIUM SALT HAVING ABSORPTION WAVELENGTH SHORTER THAN 350 NANOMETERS AND A THERMALLY REACTIVE COUPLER CONTAINED WITHIN RECORDING LAYER COATED ONTO SUPPORT; STORAGE STABILITY, PHOTOSTABILITY, HIGH COLOR DENSITY | FUJI PHOTO FILM CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| US-5998082-A | DIHYDROCARBYLOXYPHENYL DIAZONIUM COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| US-5935757-A | HIGH COLOR DEVELOPING SENSITIVITY AND EXCELLENT STORABILITY. USING AN ESTER- OR AMIDE CONTAINING SULFOAMIDOBENZENE IN A LAYER CONTAINING A DIAZONIUM SALT AND A REACTIVE COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0827020-A1 | Thermal recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |
| US-4138258-A | NONDIFFUSING CYAN COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1979-02-06 | — | — | US | disclosed |
| US-4046573-A | COLOR PHOTOGRAPHIC MATERIALS | FUJI PHOTO FILM CO., LTD. (JA) | 1977-09-06 | — | — | US | disclosed |
| US-4028106-A | CYAN COUPLER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1977-06-07 | — | — | US | disclosed |