Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 7/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010865 | 0.83 | ALDH1A1 (0.47) | ITGA4ITGB7ALDH1A1IDO1CYP2D6 | |
| SCHEMBL19537444 | 0.83 | ALDH1A1 (0.46) | ITGA4ITGB7ALDH1A1IDO1HSD11B1 | |
| Hydrochloric Acid SCHEMBL30714941 | 0.82 | ALDH1A1 (0.45) | ITGA4ITGB7ALDH1A1IDO1HSD11B1 | |
| SCHEMBL19531854 | 0.79 | ALDH1A1 (0.43) | ITGA4ITGB7ALDH1A1IDO1HSD11B1 | |
| SCHEMBL10002454 | 0.78 | OPRM1 (0.49) | ALDH1A1HSD11B1LMNAVNN1 | |
| SCHEMBL25460767 | 0.78 | ALDH1A1 (0.53) | ITGA4ITGB7ALDH1A1IDO1HSD11B1 | |
| SCHEMBL25460766 | 0.78 | IDO1 (0.52) | ITGA4ITGB7ALDH1A1IDO1HSD11B1 | |
| SCHEMBL21380384 | 0.78 | ALDH1A1 (0.50) | ITGA4ITGB7ALDH1A1IDO1HSD11B1 | |
| SCHEMBL2592593 | 0.77 | ALDH1A1 (0.52) | ITGA4ITGB7ALDH1A1IDO1HSD11B1 | |
| SCHEMBL2593341 | 0.77 | ITGA4 (0.48) | ITGA4ITGB7ALDH1A1IDO1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113395898-A | Compositions for treating citrus disease and promoting yield enhancement of row crops | 斯波根生物技术公司 | 2021-09-14 | — | — | CN | disclosed |
| CN-111491654-A | Biologically active polypeptides for improving the protection, growth and productivity of plants | 斯波根生物技术公司 | 2020-08-04 | — | — | CN | disclosed |
| US-8314254-B2 | Substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2012-11-20 | — | — | US | disclosed |
| US-8119570-B1 | 3-biphenyl-substituted-3-substituted-4-ketolactam and ketolactone and their utilization as pesticide | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20120028804-A1 | 3-BIPHENYL-SUBSTITUTED-3-SUBSTITUTED-4-KETOLACTAM AND KETOLACTONE AND THEIR UTILIZATION AS PESTICIDE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-02-02 | — | — | US | disclosed |
| US-8063096-B2 | Spirocyclic 3-phenyl-3substituted-4-ketolactams and-lactones | BAYER CROPSCIENCE AG (DE) | 2011-11-22 | — | — | US | disclosed |
| US-8058452-B2 | Pyrazolyl-substituted heterocycles and their use as phytosanitary products | BAYER CROPSCIENCE AG (US) | 2011-11-15 | — | — | US | disclosed |
| US-20110143942-A1 | Pyrazolyl-Substituted Heterocycles and Their Use as Phytosanitary Products | FISCHER REINER | 2011-06-16 | — | — | US | disclosed |
| EP-2314161-A1 | Controlled-release insecticidal formulations | Bayer Cropscience LP (US) | 2011-04-27 | — | — | EP | disclosed |
| US-7928037-B2 | 3-biphenyl-substituted-3-substituted-4-ketolactam and ketolactone and their utilization as pesticide | BAYER CROPSCIENCE AG (DE) | 2011-04-19 | — | — | US | disclosed |
| US-20050090400-A1 | 3-biphenyl-substituted-3-substituted-4-ketolactam and ketolactone and their utilization as pesticide | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-04-28 | — | — | US | disclosed |
| US-20050070707-A1 | microbicides, pesticides and herbicides | BAYER CROPSCIENCE AG (DE) | 2005-03-31 | — | — | US | disclosed |
| US-20050049285-A1 | Dichloropyridyl methyl cyanamidines | BAYER CROPSCIENCE AG (DE) | 2005-03-03 | — | — | US | disclosed |
| US-20050032885-A1 | Spirocyclic 3-phenyl-3-substituted 4-ketolactams and 4-ketolactones | BAYER CROPSCIENCE AG (DE) | 2005-02-10 | — | — | US | disclosed |
| US-20050009839-A1 | Novel azoles having an insecticidal action | BAYER CROPSCIENCE AG (DE) | 2005-01-13 | — | — | US | disclosed |
| US-6838462-B2 | Insecticidal azoles | BAYER CROPSCIENCE LP (DE) | 2005-01-04 | — | — | US | disclosed |
| US-20040242664-A1 | Pyrazolyl-substituted heterocycles and their use as phytosanitary products | BAYER CROPSCIENCE AG (DE) | 2004-12-02 | — | — | US | disclosed |
| US-20040242662-A1 | Azinyl sulfonylimidazoles for use as microbicidal agents | BAYER CROPSCIENCE AG (DE) | 2004-12-02 | — | — | US | disclosed |
| US-20040209896-A1 | Novel insecticidal azoles | BAYER CROPSCIENCE AG (DE) | 2004-10-21 | — | — | US | disclosed |
| US-20040077880-A1 | Sulfonylpyrroles | BAYER CROPSCIENCE AG (DE) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077880-A1 | Sulfonylpyrroles | CBR3, CBR1, CYCS | ITGA4 3668/4885ITGB7 4232/4885ALDH1A1 2270/4885 |
| US-20120028804-A1 | 3-BIPHENYL-SUBSTITUTED-3-SUBSTITUTED-4-KETOLACTAM AND KETOLACTONE AND THEIR UTILIZATION AS PESTICIDE | CYP2B6, CYP2A6, CYP1B1 | ITGA4 2879/4885ITGB7 3997/4885ALDH1A1 753/4885 |
| US-20050090400-A1 | 3-biphenyl-substituted-3-substituted-4-ketolactam and ketolactone and their utilization as pesticide | CYP2B6, CYP2A6, CYP1B1 | ITGA4 3324/4885ITGB7 4097/4885ALDH1A1 1048/4885 |
| US-20040242664-A1 | Pyrazolyl-substituted heterocycles and their use as phytosanitary products | CYP1A1, CYP1B1, CYP8B1 | ITGA4 4670/4885ITGB7 4495/4885ALDH1A1 1146/4885 |
| US-20110143942-A1 | Pyrazolyl-Substituted Heterocycles and Their Use as Phytosanitary Products | DDT, HPD, CYP8B1 | ITGA4 4796/4885ITGB7 4611/4885ALDH1A1 2320/4885 |
| US-20050009839-A1 | Novel azoles having an insecticidal action | CYP51A1, DDT, CRY1 | ITGA4 4216/4885ITGB7 4217/4885ALDH1A1 3099/4885 |
| US-20040242662-A1 | Azinyl sulfonylimidazoles for use as microbicidal agents | CBR1, MASTL, AZI2 | ITGA4 1086/4885ITGB7 985/4885ALDH1A1 715/4885 |
| US-20050070707-A1 | microbicides, pesticides and herbicides | DDT, CX3CR1, MSR1 | ITGA4 2683/4885ITGB7 1710/4885ALDH1A1 286/4885 |
| US-20040209896-A1 | Novel insecticidal azoles | CYP51A1, CRY1, CYP4X1 | ITGA4 3426/4885ITGB7 3205/4885ALDH1A1 1609/4885 |
| US-20050049285-A1 | Dichloropyridyl methyl cyanamidines | MRPL21, DDT, FBL | ITGA4 2349/4885ITGB7 2793/4885ALDH1A1 2077/4885 |
| US-20050032885-A1 | Spirocyclic 3-phenyl-3-substituted 4-ketolactams and 4-ketolactones | PDHX, CYP2A6, CYP2D6 | ITGA4 2470/4885ITGB7 4017/4885ALDH1A1 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.