Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162456 | 0.98 | BBOX1 (0.35) | BBOX1 | |
| Water SCHEMBL22773556 | 0.97 | BBOX1 (0.34) | BBOX1 | |
| Betaine SCHEMBL7991073 | 0.88 | TSHR (0.35) | — | |
| SCHEMBL4056939 | 0.85 | BBOX1 (0.53) | BBOX1 | |
| SCHEMBL973803 | 0.80 | APP (0.37) | — | |
| Water SCHEMBL7896367 | 0.79 | THRB (0.45) | — | |
| SCHEMBL7770974 | 0.79 | CES2 (0.37) | — | |
| Water SCHEMBL140337 | 0.78 | TSHR (0.41) | BBOX1 | |
| SCHEMBL16788554 | 0.78 | BBOX1 (0.38) | BBOX1 | |
| SCHEMBL15830120 | 0.77 | THRB (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414867-B1 | POLYMERS AND THEIR SYNTHESIS | UNILEVER PLC (GB) | 2007-03-14 | — | — | EP | claimed |
| US-7153821-B2 | Use of graft polymers in fabric cleaning | UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC (US) | 2006-12-26 | — | — | US | claimed |
| US-7041730-B2 | Polymers and their synthesis | UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. (US) | 2006-05-09 | — | — | US | claimed |
| EP-1409629-B1 | USE OF GRAFT POLYMERS IN FABRIC CLEANING | UNILEVER PLC (GB) | 2005-10-19 | — | — | EP | claimed |
| US-20040176534-A1 | Polymers and their synthesis | Henkel IP & Holding GmbH (DE) | 2004-09-09 | — | — | US | claimed |
| US-20030161804-A1 | Self-adhesive cationic or amphoteric free-radical polymers and cosmetic use thereof | L'OREAL (FR) | 2003-08-28 | — | — | US | claimed |
| US-6403073-B1 | MIXTURE CONTAINING ADDITION POLYMER | L'OREAL S.A. (FR) | 2002-06-11 | — | — | US | claimed |
| EP-0889940-A1 | ELECTROSPRAYABLE RELEASE COATING | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-01-13 | — | — | EP | claimed |
| US-5858545-A | COMPRISING AN UNSATURATED MONOMER, A POLYSILOXANE HAVING UNSATURATED END GROUPS AND ONE OR MORE NONVOLATILE CONDUCTIVITY ENHANCER SOLUBLE IN THE MONOMER AND NOT INTERFERING WITH THE COPOLYMERIZATION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-01-12 | — | — | US | claimed |
| WO-1997035941-A1 | ELECTROSPRAYABLE RELEASE COATING | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-10-02 | — | — | WO | claimed |
| US-5523367-A | DISPOSABLE PRODUCTS | PHILLIPS PETROLEUM COMPANY (US) | 1996-06-04 | — | — | US | claimed |
| EP-1414867-B1 | POLYMERS AND THEIR SYNTHESIS | UNILEVER PLC (GB) | 2007-03-14 | — | — | EP | disclosed |
| US-7153821-B2 | Use of graft polymers in fabric cleaning | UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC (US) | 2006-12-26 | — | — | US | disclosed |
| US-7041730-B2 | Polymers and their synthesis | UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. (US) | 2006-05-09 | — | — | US | disclosed |
| EP-1409629-B1 | USE OF GRAFT POLYMERS IN FABRIC CLEANING | UNILEVER PLC (GB) | 2005-10-19 | — | — | EP | disclosed |
| US-5858545-A | COMPRISING AN UNSATURATED MONOMER, A POLYSILOXANE HAVING UNSATURATED END GROUPS AND ONE OR MORE NONVOLATILE CONDUCTIVITY ENHANCER SOLUBLE IN THE MONOMER AND NOT INTERFERING WITH THE COPOLYMERIZATION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1997035941-A1 | ELECTROSPRAYABLE RELEASE COATING | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-10-02 | — | — | WO | disclosed |
| US-5523367-A | DISPOSABLE PRODUCTS | PHILLIPS PETROLEUM COMPANY (US) | 1996-06-04 | — | — | US | disclosed |
| EP-0532687-B1 | SEMIPERMEABLE COMPOSITE MEMBRANE | TNO (NL) | 1996-04-17 | — | — | EP | disclosed |
| US-5348652-A | Ampholytic polymer | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 1994-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030161804-A1 | Self-adhesive cationic or amphoteric free-radical polymers and cosmetic use thereof | PARN, PCNA, F13A1 | BBOX1 1493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.