Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL4970338 | 0.96 | TSHR (0.42) | TSHRALDH1A1FGFR4 | |
| Acrylamide SCHEMBL5057257 | 0.93 | TSHR (0.39) | TSHRALDH1A1FGFR4 | |
| Acrylamide SCHEMBL516285 | 0.85 | TSHR (0.34) | TSHRCA2 | |
| Acrylamide SCHEMBL29153172 | 0.84 | ALDH1A1 (0.38) | TSHRALDH1A1FGFR4CA2 | |
| Acrylamide SCHEMBL23607548 | 0.81 | ALDH1A1 (0.52) | TSHRALDH1A1FGFR4 | |
| Acrylamide SCHEMBL4970334 | 0.81 | TSHR (0.34) | TSHR | |
| SCHEMBL28377038 | 0.81 | TDP1 (0.46) | TSHRCA2 | |
| Acrylamide SCHEMBL6835393 | 0.80 | TSHR (0.46) | TSHRALDH1A1FGFR4 | |
| Acrylamide SCHEMBL195051 | 0.80 | TSHR (0.46) | TSHRALDH1A1FGFR4 | |
| SCHEMBL22735032 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651546-A | Oxidation retardant composition | 莱雅公司 | 2024-03-05 | — | — | CN | claimed |
| CN-115231869-A | Thick oil thermal recovery cement slurry capable of resisting high temperature of 350 ℃ and not declining | 天津中海油服化学有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-110592945-B | Softening modifier for inorganic fibers and preparation method thereof | 保蓝行(福建)环保技术研究院有限责任公司 | 2021-12-28 | — | — | CN | claimed |
| CN-110592945-A | Softening modifier for inorganic fibers and preparation method thereof | 三河市纳诺科斯机电产品制造有限公司 | 2019-12-20 | — | — | CN | claimed |
| EP-4365258-A1 | HEAVY METAL TREATMENT AGENT, AND METHOD FOR TREATING INCINERATED ASH AND WASTEWATER USING SAME | Miyoshi Oil & Fat Co., Ltd. (JP) | 2024-05-08 | — | — | EP | disclosed |
| CN-117580926-A | Heavy metal treatment agent, incineration ash using same, and method for treating wastewater | 三吉油脂株式会社 | 2024-02-20 | — | — | CN | disclosed |
| CN-117417566-A | Water-soluble film and package | 株式会社可乐丽 | 2024-01-19 | — | — | CN | disclosed |
| CN-116444738-B | Epoxy modified acrylic acid aqueous dispersion and preparation method thereof | 泰兴盛嘉树脂有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-113227223-B | Water-soluble film and package | 株式会社可乐丽 | 2023-12-08 | — | — | CN | disclosed |
| CN-113226941-B | Water-soluble film and package | 株式会社可乐丽 | 2023-10-27 | — | — | CN | disclosed |
| CN-116253842-B | Thickened oil viscosity reducer for displacement of reservoir oil and synthesis method | 山东大明精细化工有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-113227224-B | Water-soluble film and package | 株式会社可乐丽 | 2023-09-19 | — | — | CN | disclosed |
| EP-0622412-A2 | Molded article for photographic photosensitive material, molding method and package | FUJI PHOTO FILM CO., LTD. (JP) | 1994-11-02 | — | — | EP | disclosed |
| US-5354642-A | Polymeric couplers for heat image separation systems | EASTMAN KODAK COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| EP-0582988-A2 | Polymeric couplers for heat image separation systems | EASTMAN KODAK COMPANY (US) | 1994-02-16 | — | — | EP | disclosed |
| EP-0539777-A1 | Aqueous adhesive and powder mix for its preparation | KURARAY CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |
| US-4663272-A | Silver halide photographic material containing a polymer with a photographically useful group which is rendered non-diffusive by cross-linking | FUJI PHOTO FILM CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |
| US-4642601-A | Humidity-sensitive element | HITACHI, LTD. (JP) | 1987-02-10 | — | — | US | disclosed |
| EP-0057728-B1 | MOISTURE-SENSITIVE ELEMENT, MOISTURE-SENSITIVE MATERIAL AND MANUFACTURING METHOD FOR SAME | Hitachi, Ltd. (JP) | 1986-05-28 | — | — | EP | disclosed |
| EP-0057728-A1 | MOISTURE-SENSITIVE ELEMENT, MOISTURE-SENSITIVE MATERIAL AND MANUFACTURING METHOD FOR SAME | Hitachi, Ltd. (JP) | 1982-08-18 | — | — | EP | disclosed |