SCHEMBL516371

SCHEMBL516371

CC(C)S(=O)(=O)S(=O)(=O)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GRIA1 P42261 3/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL349157 0.74
SCHEMBL31231926 0.70 KDM4E (0.33) KDM4ECYP3A4ALDH1A1GRIA1CA1
SCHEMBL5353 0.70
SCHEMBL92892 0.70
SCHEMBL10945593 0.69 GRIA1 (0.33) GRIA1CA2
SCHEMBL2223418 0.67
SCHEMBL5078889 0.67
SCHEMBL514126 0.67
SCHEMBL1470239 0.67
SCHEMBL5354 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9282741-B2 Aniline type compounds BASF SE (DE) 2016-03-15 US disclosed
US-9174967-B2 Substituted pyrazole-containing compounds and their use as pesticides BASF SE (DE) 2015-11-03 US disclosed
US-9169253-B2 Tricyclic quinoline and quinoxaline derivatives AbbVie Deutschland GmbH & Co. KG (DE) 2015-10-27 US disclosed
US-20150250173-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS BASF SE (DE) 2015-09-10 US disclosed
US-20150250175-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS BASF SE (DE) 2015-09-10 US disclosed
US-20150237858-A1 METHOD OF CONTROLLING RYANODINE-MODULATOR INSECTICIDE RESISTANT INSECTS BASF SE (DE) 2015-08-27 US disclosed
US-20150216166-A1 Aniline Type Compounds BASF SE (DE) 2015-08-06 US disclosed
US-9096583-B2 Substituted 1,2,5-oxadiazole compounds and their use as herbicides II BASF SE (DE) 2015-08-04 US disclosed
US-9044016-B2 N-thio-anthranilamide compounds and their use as pesticides BASF SE (DE) 2015-06-02 US disclosed
US-9006485-B2 Aniline type compounds BASF SE (DE) 2015-04-14 US disclosed
US-20140179519-A1 N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2014-06-26 US disclosed
US-20140155451-A1 Aniline Type Compounds BASF SE (DE) 2014-06-05 US disclosed
US-20140155264-A1 N-Thio-Anthranilamide Compounds and Their Use as Pesticides BASF SE (DE) 2014-06-05 US disclosed
US-20140080813-A1 TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES ABBVIE DEUTSCHLAND (DE) 2014-03-20 US disclosed
US-20140080814-A1 TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES AbbVie Deutschland GmbH & Co. KG (DE) 2014-03-20 US disclosed
US-8653000-B2 Imine substituted 2,4-diaryl-pyrroline derivatives as pesticides BASF SE (DE) 2014-02-18 US disclosed
US-20130190378-A1 Imine substituted 2,4-diaryl-pyrroline derivatives as pesticides BASF SE (DE) 2013-07-25 US disclosed
US-20130184320-A1 Imine Compounds BASF SE (DE) 2013-07-18 US disclosed
US-20120291159-A1 Azoline Compounds for Combating Invertebrate Pests BASF SE (DE) 2012-11-15 US disclosed
US-20120030841-A1 Isoxazoline compounds for combating invertebrate pests BASF SE (DE) 2012-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140080813-A1 TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES HTR2C, HTR2A, HTR5A KDM4E 3830/4885CYP3A4 279/4885ALDH1A1 3553/4885
US-20150216166-A1 Aniline Type Compounds ADORA3, AKT1S1, PIK3C2A KDM4E 4258/4885CYP3A4 851/4885ALDH1A1 1998/4885
US-20140179519-A1 N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES NAT1, ANTXR2, ATL3 KDM4E 3343/4885CYP3A4 1272/4885ALDH1A1 2790/4885
US-20150250173-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS AADAC, ARSA, SIRT7 KDM4E 1796/4885CYP3A4 1400/4885ALDH1A1 1423/4885
US-20140155264-A1 N-Thio-Anthranilamide Compounds and Their Use as Pesticides NAT1, ANTXR2, ATL3 KDM4E 4231/4885CYP3A4 1397/4885ALDH1A1 2605/4885
US-20140080814-A1 TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES HTR2C, HTR2A, HTR5A KDM4E 3830/4885CYP3A4 279/4885ALDH1A1 3553/4885
US-20120030841-A1 Isoxazoline compounds for combating invertebrate pests PRDX5, PRDX1, PRDX2 KDM4E 1400/4885CYP3A4 791/4885ALDH1A1 2028/4885
US-20140155451-A1 Aniline Type Compounds ADORA3, AKT1S1, PIK3C2A KDM4E 4258/4885CYP3A4 851/4885ALDH1A1 1998/4885
US-20150250175-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS MCU, AGK, MLYCD KDM4E 2270/4885CYP3A4 1350/4885ALDH1A1 2435/4885
US-20120291159-A1 Azoline Compounds for Combating Invertebrate Pests CRY1, PIR, DDT KDM4E 576/4885CYP3A4 434/4885ALDH1A1 2327/4885
US-20130190378-A1 Imine substituted 2,4-diaryl-pyrroline derivatives as pesticides DDT, PIR, INMT KDM4E 440/4885CYP3A4 729/4885ALDH1A1 2168/4885
US-20130184320-A1 Imine Compounds INMT, PNMT, IPO5 KDM4E 1586/4885CYP3A4 2396/4885ALDH1A1 2253/4885
US-20150237858-A1 METHOD OF CONTROLLING RYANODINE-MODULATOR INSECTICIDE RESISTANT INSECTS RYR2, RYR1, CRY1 KDM4E 209/4885CYP3A4 837/4885ALDH1A1 3478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.