SCHEMBL5199762

SCHEMBL5199762

NCCn1c(=O)n(CCN)c(=O)n(CCN)c1=O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35
TDP1 Q9NUW8 2/20 0.33
RXRA P19793 1/20 0.33
ALOX15 P16050 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
TP53 P04637 1/20 0.32
HBB P68871 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ADORA2B P29275 1/20 0.31
HEXA P06865 1/20 0.31
HEXB P07686 1/20 0.31
APEX1 P27695 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25191860 0.89 ADORA2B (0.35) CYP3A4TDP1RXRAADORA2B
SCHEMBL30976972 0.87 GSK3B (0.41) ADORA2B
SCHEMBL24650044 0.87 CYP3A4 (0.33) CYP3A4TDP1
SCHEMBL8510636 0.81 TDP1 (0.37) CYP3A4TDP1RXRASMN1; SMN2HEXA
SCHEMBL5198850 0.81 APEX1 (0.54) CYP3A4SMN1; SMN2APEX1
SCHEMBL21986055 0.81 NPSR1 (0.58) NPSR1SMN1; SMN2
SCHEMBL4965040 0.77 CA12 (0.42) TDP1RXRA
SCHEMBL25194183 0.73 PIM1 (0.34) TDP1RXRAHEXAHEXBAPEX1
SCHEMBL5199211 0.69 APEX1 (0.34) SMN1; SMN2APEX1
SCHEMBL11264592 0.69 ALDH1A1 (0.54) TDP1RXRANPSR1ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119161379-A Intumescent nitrogen-phosphorus flame retardant and preparation method thereof 南京林业大学 2024-12-20 CN claimed
US-20260144748-A1 POLYOL-BASED MULTI-FUNCTIONAL COMPOUNDS FOR MEDICAL APPLICATIONS AND HYDROGELS FORMED FROM SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-28 US disclosed
US-20260144900-A1 IN VIVO CROSSLINKABLE HYDROGELS WITH GOLD NANOPARTICLES FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-28 US disclosed
US-20260020859-A1 MATERIALS FOR CONFORMABLE FILLABLE MEDICAL BALLOONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-01-22 US disclosed
US-20260021223-A1 HYDROGEL FILLERS FOR CONFORMABLE FILLABLE MEDICAL BALLOONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-01-22 US disclosed
US-20250332292-A1 IN VIVO CROSSLINKABLE HYDROGELS WITH COVALENTLY ATTACHED DYE FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-10-30 US disclosed
WO-2025226800-A1 IN VIVO CROSSLINKABLE HYDROGELS WITH COVALENTLY ATTACHED DYE FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-10-30 WO disclosed
US-20250248935-A1 SYSTEMS AND METHODS FOR ON-DEMAND CLEAVAGE OF HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-08-07 US disclosed
US-20250059237-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-02-20 US disclosed
CN-119161379-A Intumescent nitrogen-phosphorus flame retardant and preparation method thereof 南京林业大学 2024-12-20 CN disclosed
EP-1352921-B1 EXTRUDED STYRENE RESIN FOAM AND PROCESS FOR PRODUCING THE SAME KANEKA CORP (JP) 2007-02-14 EP disclosed
EP-1752486-A1 Extruded styrene resin foam and process for producing the same Kaneka Corporation (JP) 2007-02-14 EP disclosed
US-6841581-B2 Extruded styrene resin foam and process for producing the same KANEKA CORPORATION (JP) 2005-01-11 US disclosed
US-20030220408-A1 Extruded styrene resin foam and process for producing the same KANEKA CORPORATION 2003-11-27 US disclosed
EP-1352921-A1 EXTRUDED STYRENE RESIN FOAM AND PROCESS FOR PRODUCING THE SAME KANEKA CORPORATION (JP) 2003-10-15 EP disclosed
US-4806574-A Ultraviolet curable coatings for optical glass fiber based on a polyfunctional core DESOTO, INC. (US) 1989-02-21 US disclosed
US-4728697-A DIELECTRIC COATINGS FOR METAL CONDUCTORS GENERAL ELECTRIC COMPANY (US) 1988-03-01 US disclosed
EP-0223958-A2 Crosslinked copolyamideimides and method for their preparation GENERAL ELECTRIC COMPANY (US) 1987-06-03 EP disclosed
EP-0209641-A2 Ultraviolet curable coatings for optical glass fiber base on a polyfunctional core DeSOTO, INC. (US) 1987-01-28 EP disclosed
US-4543376-A AS A BINDER A MIXTURE OF A POLYADDUCT, POLYCONDENSATE, OR HYDROXYL OR AMINE-CONTAINING POLYMER, AND A POLYAMINE-CYCLIC CARBONIC ACID ESTER REACTION PRODUCT BASF AKTIENGESELLSCHAFT (DE) 1985-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250332292-A1 IN VIVO CROSSLINKABLE HYDROGELS WITH COVALENTLY ATTACHED DYE FOR MEDICAL APPLICATIONS CD44, CRYAA, ILK CYP3A4 3900/4885TDP1 991/4885RXRA 1793/4885
US-20250248935-A1 SYSTEMS AND METHODS FOR ON-DEMAND CLEAVAGE OF HYDROGELS PLG, FGB, ADAM33 CYP3A4 3580/4885TDP1 276/4885RXRA 2940/4885
US-20250059237-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES AND MEDICAL HYDROGELS FORMED THEREFROM HDGF, IAPP, QRFPR CYP3A4 4803/4885TDP1 3211/4885RXRA 1567/4885
US-20260021223-A1 HYDROGEL FILLERS FOR CONFORMABLE FILLABLE MEDICAL BALLOONS H1-5, H1-2, H1-3 CYP3A4 3136/4885TDP1 3701/4885RXRA 2382/4885
US-20260020859-A1 MATERIALS FOR CONFORMABLE FILLABLE MEDICAL BALLOONS SMCHD1, KDM8, H1-5 CYP3A4 2149/4885TDP1 3816/4885RXRA 1994/4885
US-20260144900-A1 IN VIVO CROSSLINKABLE HYDROGELS WITH GOLD NANOPARTICLES FOR MEDICAL APPLICATIONS KLK3, BPHL, BRDT CYP3A4 2379/4885TDP1 2922/4885RXRA 3093/4885
US-20260144748-A1 POLYOL-BASED MULTI-FUNCTIONAL COMPOUNDS FOR MEDICAL APPLICATIONS AND HYDROGELS FORMED FROM SAME CD44, PAM, PLOD3 CYP3A4 2002/4885TDP1 3513/4885RXRA 1929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.