Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5256531 | 0.83 | L3MBTL1 (0.49) | POLBHTTTYMP | |
| SCHEMBL1346299 | 0.78 | IDH1 (0.49) | POLBKDM4EALDH1A1TYMP | |
| SCHEMBL5907208 | 0.78 | CA12 (0.41) | POLBKDM4EALDH1A1TYMP | |
| SCHEMBL15285375 | 0.76 | CYP1A2 (0.49) | KDM4EALDH1A1PDE3BPDE3ATYMP | |
| SCHEMBL3728677 | 0.75 | LTA4H (0.52) | POLBKDM4EALDH1A1GAAHTT | |
| SCHEMBL5199231 | 0.75 | ALDH1A1 (0.47) | POLBKDM4EALDH1A1GAAHTT | |
| SCHEMBL6472545 | 0.73 | MAOB (0.50) | POLBKDM4EALDH1A1GAA | |
| SCHEMBL27796132 | 0.72 | ALDH1A1 (0.43) | POLBKDM4EALDH1A1GAAHTT | |
| SCHEMBL3655327 | 0.71 | RXRA (0.43) | POLB | |
| SCHEMBL2093881 | 0.69 | HTR1A (0.52) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365337-A1 | PYRIDONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS | Selvita S.A. (PL) | 2018-08-29 | — | — | EP | disclosed |
| WO-2017068064-A1 | PYRIDONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS | SELVITA S.A. (PL) | 2017-04-27 | — | — | WO | disclosed |
| US-20070299065-A1 | Tetrahydropyran Derivatives as Antidiabetics | MERCK PATENT GMBH (DE) | 2007-12-27 | — | — | US | disclosed |
| EP-1817323-A1 | TETRAHYDROPYRANE DERIVATIVES FOR USE AS ANTIDIABETICS | MERCK PATENT GmbH (DE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006058597-A1 | TETRAHYDROPYRANE DERIVATIVES FOR USE AS ANTIDIABETICS | MERCK PATENT GMBH (DE) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299065-A1 | Tetrahydropyran Derivatives as Antidiabetics | GPR119, GLP1R, INSR | PDE4A 1687/4885PDE4B 2434/4885PDE4C 3262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.