Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 5/20 | 0.42 |
| ▸ | TACR1 | P25103 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2695856 | 0.88 | NR1H2 (0.46) | NR1H2LMNATSHRALOX5APFEN1 | |
| SCHEMBL1922847 | 0.88 | NR1H2 (0.46) | NR1H2LMNATSHRALOX5APFEN1 | |
| SCHEMBL31257884 | 0.81 | NR1H2 (0.42) | NR1H2TACR1PARP1 | |
| SCHEMBL30502301 | 0.78 | HTR2C (0.44) | NR1H2TACR1LMNATSHRPARP1 | |
| SCHEMBL31437077 | 0.77 | ALDH1A1 (0.43) | TACR1LMNAMAPT | |
| SCHEMBL2640496 | 0.77 | NR1H2 (0.45) | NR1H2TACR1RIPK1NR1H3PARP1 | |
| SCHEMBL6500495 | 0.77 | MGLL (0.41) | TSHRMAPT | |
| SCHEMBL28052467 | 0.77 | TACR1 (0.40) | NR1H2TACR1LMNATSHRNR1H3 | |
| SCHEMBL17041234 | 0.76 | RIPK1 (0.50) | LMNATSHRNPSR1MAPTRIPK1 | |
| SCHEMBL8140446 | 0.76 | PARP1 (0.43) | NR1H2TACR1MAPTNR1H3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417184-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | OREAL (FR) | 2007-08-29 | — | — | EP | claimed |
| US-6956040-B2 | Oxazolidinone piperazinyl derivatives as potential antimicrobials | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-18 | — | — | US | disclosed |
| US-20040254162-A1 | Oxazolidinone derivatives as antimicrobials | RANBAXY LABORATORIES LIMITED (IN) | 2004-12-16 | — | — | US | disclosed |
| US-6734307-B2 | USE AGAINST MULTIPLY RESISTANT GRAM POSITIVE PATHOGENS; HAVE A DIAZINE MOIETY ATTACHED TO THE PHENYLOXAZOLIDINONE WHICH IS FURTHER SUBSTITUTED BY HETEROCYCLIC, ARYL, SUBSTITUTED ARYL, HETEROAROAMATIC RING | RANBAXY LABORATORIES LIMITED (IN) | 2004-05-11 | — | — | US | disclosed |
| US-20030119817-A1 | Oxazolidinone derivatives as potential antimicrobials | MEHTA ANITA (IN) | 2003-06-26 | — | — | US | disclosed |
| EP-1303511-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES, LTD. (IN) | 2003-04-23 | — | — | EP | disclosed |
| US-20020103186-A1 | Oxazolidinone derivatives as antimicrobials disease | RANBAXY LABORATORIES LIMITED (IN) | 2002-08-01 | — | — | US | disclosed |
| WO-2002006278-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119817-A1 | Oxazolidinone derivatives as potential antimicrobials | OXA1L, PDK4, SDHA | NR1H2 2510/4885TACR1 4622/4885LMNA 3345/4885 |
| US-20020103186-A1 | Oxazolidinone derivatives as antimicrobials disease | OXA1L, MLYCD, TBCD | NR1H2 2519/4885TACR1 4697/4885LMNA 2018/4885 |
| US-20040254162-A1 | Oxazolidinone derivatives as antimicrobials | PPARD, PDK4, OXA1L | NR1H2 1335/4885TACR1 4636/4885LMNA 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.